product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-β-Amyloid, x-42
catalog :
812101
quantity :
50 μg
price :
431 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1/11/03
reactivity :
human, mouse
application :
western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • ELISA; mouse; fig s8
  • ELISA; human; fig s8
Xu G, Ran Y, Fromholt S, Fu C, Yachnis A, Golde T, et al. Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathol Commun. 2015;3:72 pubmed publisher
  • western blot; mouse
Liu P, Paulson J, Forster C, Shapiro S, Ashe K, Zahs K. Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile. PLoS ONE. 2015;10:e0126317 pubmed publisher
Sun F, Jiang F, Zhang N, Li H, Tian W, Liu W. Upregulation of Prickle2 Ameliorates Alzheimer's Disease-Like Pathology in a Transgenic Mouse Model of Alzheimer's Disease. Front Cell Dev Biol. 2020;8:565020 pubmed publisher
Guan Z, Chen Z, Fu S, Dai L, Shen Y. Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis. Front Cell Neurosci. 2020;14:260 pubmed publisher
Puzzo D, Argyrousi E, Staniszewski A, Zhang H, Calcagno E, Zuccarello E, et al. Tau is not necessary for amyloid-β-induced synaptic and memory impairments. J Clin Invest. 2020;130:4831-4844 pubmed publisher
Liu P, Reed M, Kotilinek L, Grant M, Forster C, Qiang W, et al. Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration. Cell Rep. 2015;11:1760-71 pubmed publisher
Currais A, Prior M, Lo D, Jolivalt C, Schubert D, Maher P. Diabetes exacerbates amyloid and neurovascular pathology in aging-accelerated mice. Aging Cell. 2012;11:1017-26 pubmed publisher
Mastrangelo M, Bowers W. Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. BMC Neurosci. 2008;9:81 pubmed publisher
product information
Antigen :
beta-Amyloid x-42
Apps. Abbrev. :
IHC-P, WB
Cat # :
812101
Clone :
1/11/03
Item :
Purified (azide-free) anti-β-Amyloid, x-42
Isotype :
Rabbit IgG
Other Names :
Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
Size :
50 μg
Price (USD) :
431 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Rabbit
Conjugate/Tag/Label :
PUREAF
Application Notes :
This antibody is effective in immunohistochemistry (IHC-P) and immunoblotting (WB).This antibody is reactive to the C-terminus of beta amyloid and specific for the isoform that ends at the 42nd amino acid.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA