product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-LRRK2
catalog :
808201
quantity :
100 μL
price :
114 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MC.028.83.76.242
reactivity :
human, mouse
application :
western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; mouse; fig 2
  • western blot; human; fig 1
Davies P, Hinkle K, Sukar N, Sepulveda B, Mesias R, Serrano G, et al. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies. Biochem J. 2013;453:101-13 pubmed publisher
Fern xe1 ndez B, Chittoor Vinod V, Kluss J, Kelly K, Bryant N, Nguyen A, et al. Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity. J Parkinsons Dis. 2022;12:1423-1447 pubmed publisher
Wang X, Negrou E, Maloney M, Bondar V, Andrews S, Montalban M, et al. Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10. Sci Rep. 2021;11:12900 pubmed publisher
Kashgari G, Meinecke L, Gordon W, Ruiz B, Yang J, Ma A, et al. Epithelial Migration and Non-adhesive Periderm Are Required for Digit Separation during Mammalian Development. Dev Cell. 2020;52:764-778.e4 pubmed publisher
product information
Antigen :
LRRK2
Apps. Abbrev. :
IHC-P, Direct ELISA
Cat # :
808201
Clone :
MC.028.83.76.242
Item :
Purified (azide-free) anti-LRRK2
Isotype :
Mouse IgG1, κ
Other Names :
Leucine-rich repeat serine/threonine-protein kinase 2, augmented in rheumatoid arthritis 17, AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Size :
100 μL
Price (USD) :
114 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PUREAF
Immunogen :
This monoclonal antibody was raised against a peptide immunogen comprising amino acids 2069-2087 of the LRRK2 protein in mice that did not express endogenous LRRK2 protein.
Application Notes :
This antibody was generated with support from The Michael J. Fox Foundation. The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. To learn more about MJFF, please visit https://www.michaeljfox.org/www.michaeljfox.org.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA