product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-CD230 (Prion)
catalog :
808001
quantity :
100 μL
price :
528 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6D11
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig 3
Ward A, Jessop F, Faris R, Shoup D, Bosio C, Peterson K, et al. Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2. PLoS ONE. 2022;17:e0267720 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Pankiewicz J, Lizińczyk A, Franco L, Díaz J, Martá Ariza M, Sadowski M. Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype. Acta Neuropathol Commun. 2021;9:157 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1d
  • western blot; mouse; 1:1000; loading ...; fig 1b
Marshall K, Hughson A, Vascellari S, Priola S, Sakudo A, Onodera T, et al. PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection. J Virol. 2017;91: pubmed publisher
Ribes J, Patel M, Halim H, Berretta A, Tooze S, Kl xf6 hn P. Prion protein conversion at two distinct cellular sites precedes fibrillisation. Nat Commun. 2023;14:8354 pubmed publisher
Kostelanska M, Holada K. Prion Strains Differ in Susceptibility to Photodynamic Oxidation. Molecules. 2022;27: pubmed publisher
Uchiyama K, Hara H, Chida J, Pasiana A, Imamura M, Mori T, et al. Ethanolamine Is a New Anti-Prion Compound. Int J Mol Sci. 2021;22: pubmed publisher
Bistaffa E, Marín Moreno A, Espinosa J, De Luca C, Cazzaniga F, Portaleone S, et al. PMCA-generated prions from the olfactory mucosa of patients with Fatal Familial Insomnia cause prion disease in mice. elife. 2021;10: pubmed publisher
Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, et al. Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. Immunity. 2020;53:353-370.e8 pubmed publisher
Fremuntova Z, Mosko T, Soukup J, Kucerova J, Kostelanska M, Hanusova Z, et al. Changes in cellular prion protein expression, processing and localisation during differentiation of the neuronal cell line CAD 5. Biol Cell. 2020;112:1-21 pubmed publisher
Kostylev M, Tuttle M, Lee S, Klein L, Takahashi H, Cox T, et al. Liquid and Hydrogel Phases of PrPC Linked to Conformation Shifts and Triggered by Alzheimer's Amyloid-β Oligomers. Mol Cell. 2018;72:426-443.e12 pubmed publisher
Lee J, Kim M, Li L, Velumian A, Aui P, Fehlings M, et al. Nogo receptor 1 regulates Caspr distribution at axo-glial units in the central nervous system. Sci Rep. 2017;7:8958 pubmed publisher
Uchiyama K, Tomita M, Yano M, Chida J, Hara H, Das N, et al. Prions amplify through degradation of the VPS10P sorting receptor sortilin. PLoS Pathog. 2017;13:e1006470 pubmed publisher
Wu B, McDonald A, Markham K, Rich C, McHugh K, Tatzelt J, et al. The N-terminus of the prion protein is a toxic effector regulated by the C-terminus. elife. 2017;6: pubmed publisher
Morales R, Hu P, Duran Aniotz C, Moda F, Diaz Espinoza R, Chen B, et al. Strain-dependent profile of misfolded prion protein aggregates. Sci Rep. 2016;6:20526 pubmed publisher
Moda F, Le T, Aulić S, Bistaffa E, Campagnani I, Virgilio T, et al. Synthetic prions with novel strain-specified properties. PLoS Pathog. 2015;11:e1005354 pubmed publisher
Evangelisti E, Cecchi C, Cascella R, Sgromo C, Becatti M, Dobson C, et al. Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers. J Cell Sci. 2012;125:2416-27 pubmed publisher
product information
Antigen :
CD230
Apps. Abbrev. :
FC, IHC, WB, ELISA, IP
Cat # :
808001
Clone :
6D11
Item :
Purified (azide-free) anti-CD230 (Prion)
Isotype :
Mouse IgG2a, κ
Other Names :
Major prion protein, p27-30, CD230 antigen, prion protein PrP, prion-related protein
Size :
100 μL
Price (USD) :
528 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PUREAF
Application Notes :
This antibody is effective in immunoblotting (WB), immunohistochemistry (IHC), ELISA, immunoprecipitation (IP), and flow cytometry (FC).6D11 reacts with both the PrPc and PrPsc forms. The epitope falls within amino acids 93-109 of PrP.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA