product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-Tau, 6-18
catalog :
806502
quantity :
500 μL
price :
1648 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Tau 12
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • ELISA; human; loading ...; fig 1a
Ercan Herbst E, Ehrig J, Schöndorf D, Behrendt A, Klaus B, Gomez Ramos B, et al. A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer's disease brain. Acta Neuropathol Commun. 2019;7:192 pubmed publisher
  • immunocytochemistry; human; 1:100; tbl 2
  • western blot; human; 1:1000; tbl 1
  • western blot; mouse
Ercan E, Eid S, Weber C, Kowalski A, Bichmann M, Behrendt A, et al. A validated antibody panel for the characterization of tau post-translational modifications. Mol Neurodegener. 2017;12:87 pubmed publisher
Montoliu Gaya L, Benedet A, Tissot C, Vrillon A, Ashton N, Brum W, et al. Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies. Nat Aging. 2023;3:661-669 pubmed publisher
Mil xe0 Alom xe0 M, Ashton N, Shekari M, Salvad xf3 G, Ortiz Romero P, Montoliu Gaya L, et al. Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer's disease. Nat Med. 2022;28:1797-1801 pubmed publisher
Chatterjee S, Bahl E, Mukherjee U, Walsh E, Shetty M, Yan A, et al. Endoplasmic reticulum chaperone genes encode effectors of long-term memory. Sci Adv. 2022;8:eabm6063 pubmed publisher
Snellman A, Lantero Rodriguez J, Emer x161 i x10d A, Vrillon A, Karikari T, Ashton N, et al. N-terminal and mid-region tau fragments as fluid biomarkers in neurological diseases. Brain. 2022;145:2834-2848 pubmed publisher
Ashton N, Benedet A, Pascoal T, Karikari T, Lantero Rodriguez J, Brum W, et al. Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease. EBioMedicine. 2022;76:103836 pubmed publisher
Bichmann M, Prat Oriol N, Ercan Herbst E, Sch xf6 ndorf D, Gomez Ramos B, Schw xe4 rzler V, et al. SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer's disease. Mol Neurodegener. 2021;16:46 pubmed publisher
Karikari T, Emer x161 i x10d A, Vrillon A, Lantero Rodriguez J, Ashton N, Kramberger M, et al. Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer's disease diagnosis. Alzheimers Dement. 2021;17:755-767 pubmed publisher
Karikari T, Keeling S, Hill E, Lantero Rodrı Guez J, Nagel D, Becker B, et al. Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional Biochemistry. ACS Chem Neurosci. 2020;11:3117-3129 pubmed publisher
Haenig C, Atias N, Taylor A, Mazza A, Schaefer M, Russ J, et al. Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep. 2020;32:108050 pubmed publisher
Lantero Rodriguez J, Karikari T, Suarez Calvet M, Troakes C, King A, Emersic A, et al. Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline. Acta Neuropathol. 2020;140:267-278 pubmed publisher
Seraf xed n V, Razzino C, Gamella M, Pedrero M, Povedano E, Montero Calle A, et al. Disposable immunoplatforms for the simultaneous determination of biomarkers for neurodegenerative disorders using poly(amidoamine) dendrimer/gold nanoparticle nanocomposite. Anal Bioanal Chem. 2021;413:799-811 pubmed publisher
Karikari T, Pascoal T, Ashton N, Janelidze S, Benedet A, Rodriguez J, et al. Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts. Lancet Neurol. 2020;19:422-433 pubmed publisher
Rosenberg R, Fu M, Lambracht Washington D. Active full-length DNA Aβ42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology. Alzheimers Res Ther. 2018;10:115 pubmed publisher
Sengupta U, Portelius E, Hansson O, Farmer K, Castillo Carranza D, Woltjer R, et al. Tau oligomers in cerebrospinal fluid in Alzheimer's disease. Ann Clin Transl Neurol. 2017;4:226-235 pubmed publisher
Kotfis K, Zegan Barańska M, Szydłowski Ł, Zukowski M, Ely E. Methods of pain assessment in adult intensive care unit patients - Polish version of the CPOT (Critical Care Pain Observation Tool) and BPS (Behavioral Pain Scale). Anaesthesiol Intensive Ther. 2017;49:66-72 pubmed publisher
Irwin D, Cohen T, Grossman M, Arnold S, Xie S, Lee V, et al. Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies. Brain. 2012;135:807-18 pubmed publisher
product information
Antigen :
Tau 6-18
Apps. Abbrev. :
WB, IHC, ELISA
Cat # :
806502
Clone :
Tau 12
Item :
Purified (azide-free) anti-Tau, 6-18
Isotype :
Mouse IgG1
Other Names :
PHF-tau, paired helical filament-tau, neurofibrillary tangle protein, microtubule-associated protein tau, isoform 4, G protein beta1/gamma2 subunit-interacting factor 1, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND
Size :
500 μL
Price (USD) :
1648 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PUREAF
Application Notes :
This antibody is specific for an epitope that lies between amino acids 6-18 of human Tau.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA