Purified (azide-free) anti-mouse/rat β-Amyloid, 1-16 | BioLegend 805707 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified (azide-free) anti-mouse/rat β-Amyloid, 1-16

catalog :

805707

quantity :

25 μL

price :

112 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M3.2

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

BioLegend product webpage

citations: 10

Reference
Agrawal R, Larrea D, Xu Y, Shi L, Zirpoli H, Cummins L, et al. Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury. Cell Mol Neurobiol. 2023;43:2219-2241 pubmed publisher
Brandimarti R, Irollo E, Meucci O. The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities. Mol Neurobiol. 2022;: pubmed publisher
Joly S, Rodriguez L, Pernet V. The Lack of Amyloidogenic Activity Is Persistent in Old WT and APPswe/PS1ΔE9 Mouse Retinae. Int J Mol Sci. 2021;22: pubmed publisher
Socodato R, Portugal C, Canedo T, Rodrigues A, Almeida T, Henriques J, et al. Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration. Cell Rep. 2020;31:107796 pubmed publisher
Tambini M, Norris K, D ADAMIO L. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation. elife. 2020;9: pubmed publisher
Gulisano W, Melone M, Ripoli C, Rosaria Tropea M, Li Puma D, Giunta S, et al. Neuromodulatory action of picomolar extracellular Aβ42 oligomers on pre- and postsynaptic mechanisms underlying synaptic function and memory. J Neurosci. 2019;: pubmed publisher
Wang W, Hou T, Jia L, Wu Q, Quan M, Jia J. Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury. EBioMedicine. 2019;42:174-187 pubmed publisher
Sun J, Carlson Stevermer J, Das U, Shen M, Delenclos M, Snead A, et al. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nat Commun. 2019;10:53 pubmed publisher
Miranda A, Lasiecka Z, Xu Y, Neufeld J, Shahriar S, Simoes S, et al. Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures. Nat Commun. 2018;9:291 pubmed publisher
Daria A, Colombo A, Llovera G, Hampel H, Willem M, Liesz A, et al. Young microglia restore amyloid plaque clearance of aged microglia. EMBO J. 2017;36:583-603 pubmed publisher

product information

Antigen :

beta-Amyloid 1-16

Apps. Abbrev. :

WB, ICC, IP, ELISA Detection, ELISA Capture

Cat # :

805707

Clone :

M3.2

Item :

Purified (azide-free) anti-mouse/rat β-Amyloid, 1-16

Isotype :

Mouse IgG1, κ

Other Names :

AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein

Size :

25 μL

Price (USD) :

112 USD

Reactivity :

Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PUREAF

Immunogen :

The epitope has been determined to be within residues 10-15 of murine Aβ.

Application Notes :

Clone M3.2 recognizes a rodent sequence of Aß, ß-CTF, sAPP-a, and full length APP. Clone 3.2 has negligible cross reactivity with human isoforms of APP and beta amyloid.;

more info or order :

BioLegend product webpage