HRP anti-β-Amyloid, 1-42 | BioLegend 805507 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

HRP anti-β-Amyloid, 1-42

catalog :

805507

quantity :

200 μL

price :

633 USD

clonality :

monoclonal

host :

mouse

conjugate :

HRP

clone name :

12F4

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
ELISA; mouse; loading ...; fig 3d	Casali B, Reed Geaghan E, Landreth G. Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer's disease. J Neuroinflammation. 2018;15:43 pubmed publisher
	Liu X, Su Y, Huang Z, Lv J, Gu C, Li Z, et al. Sleep loss potentiates Th17-cell pathogenicity and promotes autoimmune uveitis. Clin Transl Med. 2023;13:e1250 pubmed publisher
	Casali B, Macpherson K, Reed Geaghan E, Landreth G. Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies. Neurobiol Dis. 2020;142:104956 pubmed publisher
	Lambert A, Hallinan J, Werther R, Głów D, Stoddard B. Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition. Structure. 2020;28:760-775.e8 pubmed publisher
	Cheng Hathaway P, Reed Geaghan E, Jay T, Casali B, Bemiller S, Puntambekar S, et al. The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease. Mol Neurodegener. 2018;13:29 pubmed publisher
	Savage M, Kalinina J, Wolfe A, Tugusheva K, Korn R, Cash Mason T, et al. A sensitive a? oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid. J Neurosci. 2014;34:2884-97 pubmed publisher
	Sundaram R, Kasinathan C, Stein S, SUNDARAM P. Novel Detox Gel Depot sequesters ?-Amyloid Peptides in a mouse model of Alzheimer's Disease. Int J Pept Res Ther. 2012;18:99-106 pubmed
	Cenini G, Dowling A, Beckett T, Barone E, Mancuso C, Murphy M, et al. Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. Biochim Biophys Acta. 2012;1822:130-8 pubmed publisher
	Mastrangelo M, Bowers W. Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. BMC Neurosci. 2008;9:81 pubmed publisher

product information

Antigen :

beta-Amyloid 1-42

Apps. Abbrev. :

IHC-P, WB

Cat # :

805507

Clone :

12F4

Item :

HRP anti-β-Amyloid, 1-42

Isotype :

Mouse IgG1, κ

Other Names :

AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein

Size :

200 μL

Price (USD) :

633 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

HRP

Application Notes :

This antibody is effective in ELISA, Immunoblotting (WB) and Immunohistochemistry on frozen and formalin-fixed paraffin-embedded tissues (IHC-P, IHC-F).Reactive to the c-terminus of beta amyloid and specific for the isoform ending at the 42nd amino acid.Additional reported applications (for the relevant formats) includes: immunohistochemical staining of paraformaldehyde-fixed frozen sections^6 and ELISA^3,4,5.;

more info or order :

BioLegend product webpage