Published Application/Species/Sample/Dilution | Reference |
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- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2h
| Shi H, Yin Z, Koronyo Y, Fuchs D, Sheyn J, Davis M, et al. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia. Acta Neuropathol Commun. 2022;10:136 pubmed publisher
|
- immunohistochemistry - free floating section; mouse; loading ...; fig 1e
| Ma C, Hunt J, Selenica M, Sanneh A, Sandusky Beltran L, Watler M, et al. Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. Front Immunol. 2020;11:582998 pubmed publisher
|
- immunohistochemistry - free floating section; mouse; loading ...; fig 3g
| Martorell A, Paulson A, Suk H, Abdurrob F, Drummond G, Guan W, et al. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. 2019;177:256-271.e22 pubmed publisher
|
- immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 5a
- western blot; mouse; 1:1000
| Klementieva O, Willén K, Martinsson I, Israelsson B, Engdahl A, Cladera J, et al. Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP. Nat Commun. 2017;8:14726 pubmed publisher
|
- ELISA; human; 1 ug/ml; fig 6
| Miners J, Palmer J, Love S. Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease. Brain Pathol. 2016;26:533-41 pubmed publisher
|
- western blot; mouse; 1:500; fig 4
| Owais K, Huang T, Mahmood F, Hubbard J, Saraf R, Bardia A, et al. Cardiopulmonary Bypass Decreases Activation of the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway in Diabetic Human Myocardium. Ann Thorac Surg. 2015;100:1636-45; discussion 1645 pubmed publisher
|
- western blot; mouse; 1:500; fig 4
| Tousseyn T, Bajsarowicz K, Sánchez H, Gheyara A, Oehler A, Geschwind M, et al. Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes. J Neuropathol Exp Neurol. 2015;74:873-88 pubmed publisher
|
| Ashby E, Miners J, Kumar S, Walter J, Love S, Kehoe P. Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Neuropathol Appl Neurobiol. 2015;41:428-44 pubmed publisher
|
| Willumsen N, Arber C, Lovejoy C, Toombs J, Alatza A, Weston P, et al. The PSEN1 E280G mutation leads to increased amyloid-β43 production in induced pluripotent stem cell neurons and deposition in brain tissue. Brain Commun. 2023;5:fcac321 pubmed publisher
|
| Jin J, Xu Z, Zhang L, Zhang C, Zhao X, Mao Y, et al. Gut-derived β-amyloid: Likely a centerpiece of the gut-brain axis contributing to Alzheimer's pathogenesis. Gut Microbes. 2023;15:2167172 pubmed publisher
|
| Nick H, Fenik P, Zhu Y, Veasey S. Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus. Front Aging Neurosci. 2022;14:1025402 pubmed publisher
|
| Piccirillo S, Preziuso A, Amoroso S, Serfilippi T, Miceli F, Magi S, et al. A new K+channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer's disease. Cell Death Discov. 2022;8:391 pubmed publisher
|
| Bishay J, Beckett T, Lai A, Hill M, McMahon D, McLaurin J. Venular amyloid accumulation in transgenic Fischer 344 Alzheimer's disease rats. Sci Rep. 2022;12:15287 pubmed publisher
|
| Gutknecht M, Kaku H, Rothstein T. Microparticle immunocapture assay for quantitation of protein multimer amount and size. Cell Rep Methods. 2022;2:100214 pubmed publisher
|
| Plowey E, Bussiere T, Rajagovindan R, Sebalusky J, Hamann S, von Hehn C, et al. Alzheimer disease neuropathology in a patient previously treated with aducanumab. Acta Neuropathol. 2022;144:143-153 pubmed publisher
|
| Jord xe0 Siquier T, Petrel M, Kouskoff V, Smailovic U, Cordeli xe8 res F, Frykman S, et al. APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease?. Alzheimers Dement. 2022;18:2099-2116 pubmed publisher
|
| Maxwell A, Yuan P, Rivera B, Schaaf W, Mladinov M, Prasher V, et al. Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer's disease pathology in Down syndrome. Acta Neuropathol Commun. 2021;9:201 pubmed publisher
|
| Koh H, Lee S, Lee H, Min J, Iwatsubo T, Teunissen C, et al. Targeting MicroRNA-485-3p Blocks Alzheimer's Disease Progression. Int J Mol Sci. 2021;22: pubmed publisher
|
| Kim H, Kim S, Park S, Park G, Shin H, Park M, et al. Administration of Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI Improves Cognitive and Memory Function in the Mouse Model of Alzheimer's Disease. Front Aging Neurosci. 2021;13:709091 pubmed publisher
|
| Ruiz Riquelme A, Mao A, Barghash M, Lau H, Stuart E, Kovacs G, et al. Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice. Acta Neuropathol Commun. 2021;9:83 pubmed publisher
|
| Owen J, Zhu Y, Fenik P, Zhan G, Bell P, Liu C, et al. Late-in-life neurodegeneration after chronic sleep loss in young adult mice. Sleep. 2021;44: pubmed publisher
|
| Olah M, Menon V, Habib N, Taga M, Ma Y, Yung C, et al. Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease. Nat Commun. 2020;11:6129 pubmed publisher
|
| Li K, Jiang Y, Li G, Liu T, Yang Z. Novel Multitarget Directed Tacrine Hybrids as Anti-Alzheimer's Compounds Improved Synaptic Plasticity and Cognitive Impairment in APP/PS1 Transgenic Mice. ACS Chem Neurosci. 2020;11:4316-4328 pubmed publisher
|
| Barbato C, Giacovazzo G, Albiero F, Scardigli R, Scopa C, Ciotti M, et al. Cognitive Decline and Modulation of Alzheimer's Disease-Related Genes After Inhibition of MicroRNA-101 in Mouse Hippocampal Neurons. Mol Neurobiol. 2020;57:3183-3194 pubmed publisher
|
| Parker H, Ellison S, Holley R, O Leary C, Liao A, Asadi J, et al. Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA. EMBO Mol Med. 2020;12:e11185 pubmed publisher
|
| Shi H, Koronyo Y, Rentsendorj A, Regis G, Sheyn J, Fuchs D, et al. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta Neuropathol. 2020;139:813-836 pubmed publisher
|
| Kim K, Kim M, Kim D, Kim S, Park S, Park C. Clinically accurate diagnosis of Alzheimer's disease via multiplexed sensing of core biomarkers in human plasma. Nat Commun. 2020;11:119 pubmed publisher
|
| Chan H, Xu D, Ho S, He D, Wong M, Li H. Highly sensitive quantification of Alzheimer's disease biomarkers by aptamer-assisted amplification. Theranostics. 2019;9:2939-2949 pubmed publisher
|
| Ruiz Riquelme A, Lau H, Stuart E, Goczi A, Wang Z, Schmitt Ulms G, et al. Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression. Acta Neuropathol Commun. 2018;6:26 pubmed publisher
|
| Lee C, Daggett A, Gu X, Jiang L, Langfelder P, Li X, et al. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 2018;97:1032-1048.e5 pubmed publisher
|
| Kommaddi R, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, et al. Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease. J Neurosci. 2018;38:1085-1099 pubmed publisher
|
| Kim C, Park J, Kong T, Lee S, Seo K, Choi Y, et al. Double-Injected Human Stem Cells Enhance Rehabilitation in TBI Mice Via Modulation of Survival and Inflammation. Mol Neurobiol. 2018;55:4870-4884 pubmed publisher
|
| Moreno F, Indakoetxea B, Barandiaran M, Caballero M, Gorostidi A, Calafell F, et al. The unexpected co-occurrence of GRN and MAPT p.A152T in Basque families: Clinical and pathological characteristics. PLoS ONE. 2017;12:e0178093 pubmed publisher
|
| Ahmad F, Singh K, Das D, Gowaikar R, Shaw E, Ramachandran A, et al. Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease. Antioxid Redox Signal. 2017;27:1269-1280 pubmed publisher
|
| Augé E, Cabezón I, Pelegri C, Vilaplana J. New perspectives on corpora amylacea in the human brain. Sci Rep. 2017;7:41807 pubmed publisher
|
| Savage M, Kalinina J, Wolfe A, Tugusheva K, Korn R, Cash Mason T, et al. A sensitive a? oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid. J Neurosci. 2014;34:2884-97 pubmed publisher
|
| Eimer W, Vassar R. Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal A?42 accumulation and Caspase-3 activation. Mol Neurodegener. 2013;8:2 pubmed publisher
|
| Helwig M, Hoshino A, Berridge C, Lee S, Lorenzen N, Otzen D, et al. The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. J Biol Chem. 2013;288:1114-24 pubmed publisher
|
| Sundaram R, Kasinathan C, Stein S, SUNDARAM P. Novel Detox Gel Depot sequesters ?-Amyloid Peptides in a mouse model of Alzheimer's Disease. Int J Pept Res Ther. 2012;18:99-106 pubmed
|
| Ohmi K, Zhao H, Neufeld E. Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. PLoS ONE. 2011;6:e27461 pubmed publisher
|
| Cenini G, Dowling A, Beckett T, Barone E, Mancuso C, Murphy M, et al. Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. Biochim Biophys Acta. 2012;1822:130-8 pubmed publisher
|
| Maheshwari M, Roberts J, Desutter B, Duong K, Tingling J, Fawver J, et al. Hydralazine modifies A? fibril formation and prevents modification by lipids in vitro. Biochemistry. 2010;49:10371-80 pubmed publisher
|
| Vingtdeux V, Chandakkar P, Zhao H, d Abramo C, Davies P, Marambaud P. Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-? peptide degradation. FASEB J. 2011;25:219-31 pubmed publisher
|
| Townsend M, Qu Y, Gray A, Wu Z, Seto T, Hutton M, et al. Oral treatment with a gamma-secretase inhibitor improves long-term potentiation in a mouse model of Alzheimer's disease. J Pharmacol Exp Ther. 2010;333:110-9 pubmed publisher
|
| Takami M, Nagashima Y, Sano Y, Ishihara S, Morishima Kawashima M, Funamoto S, et al. gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment. J Neurosci. 2009;29:13042-52 pubmed publisher
|
| Sudol K, Mastrangelo M, Narrow W, Frazer M, Levites Y, Golde T, et al. Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease. Mol Ther. 2009;17:2031-40 pubmed publisher
|
| Mastrangelo M, Bowers W. Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. BMC Neurosci. 2008;9:81 pubmed publisher
|