product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-β-Amyloid, 1-40
catalog :
805401
quantity :
200 μL
price :
528 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
11A50-B10
reactivity :
human, mouse
application :
ELISA, immunohistochemistry, immunohistochemistry - paraffin section, dot blot
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; fig 5d
Shi H, Yin Z, Koronyo Y, Fuchs D, Sheyn J, Davis M, et al. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia. Acta Neuropathol Commun. 2022;10:136 pubmed publisher
  • immunohistochemistry; human; 1:200; loading ...; fig 1b
Shi H, Koronyo Y, Rentsendorj A, Regis G, Sheyn J, Fuchs D, et al. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta Neuropathol. 2020;139:813-836 pubmed publisher
  • ELISA; human; 1 ug/ml; fig 6
Miners J, Palmer J, Love S. Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease. Brain Pathol. 2016;26:533-41 pubmed publisher
Shi H, Koronyo Y, Fuchs D, Sheyn J, Wawrowsky K, Lahiri S, et al. Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease. Acta Neuropathol Commun. 2020;8:202 pubmed publisher
Parker H, Ellison S, Holley R, O Leary C, Liao A, Asadi J, et al. Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA. EMBO Mol Med. 2020;12:e11185 pubmed publisher
Kim K, Kim M, Kim D, Kim S, Park S, Park C. Clinically accurate diagnosis of Alzheimer's disease via multiplexed sensing of core biomarkers in human plasma. Nat Commun. 2020;11:119 pubmed publisher
Carreras I, Aytan N, Choi J, Tognoni C, Kowall N, Jenkins B, et al. Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease. Sci Rep. 2019;9:10972 pubmed publisher
Dolfe L, Tambaro S, Tigro H, Del Campo M, Hoozemans J, Wiehager B, et al. The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ42 and Alzheimer Amyloid Plaques. J Alzheimers Dis Rep. 2018;2:27-39 pubmed publisher
Ruiz Riquelme A, Lau H, Stuart E, Goczi A, Wang Z, Schmitt Ulms G, et al. Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression. Acta Neuropathol Commun. 2018;6:26 pubmed publisher
Lee C, Daggett A, Gu X, Jiang L, Langfelder P, Li X, et al. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 2018;97:1032-1048.e5 pubmed publisher
Watts J, Condello C, Stöhr J, Oehler A, Lee J, Dearmond S, et al. Serial propagation of distinct strains of A? prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A. 2014;111:10323-8 pubmed publisher
Diomede L, di Fede G, Romeo M, Bagnati R, Ghidoni R, Fiordaliso F, et al. Expression of A2V-mutated A? in Caenorhabditis elegans results in oligomer formation and toxicity. Neurobiol Dis. 2014;62:521-32 pubmed publisher
Watanabe H, Xia D, Kanekiyo T, Kelleher R, Shen J. Familial frontotemporal dementia-associated presenilin-1 c.548G>T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice. J Neurosci. 2012;32:5085-96 pubmed publisher
Ohmi K, Zhao H, Neufeld E. Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. PLoS ONE. 2011;6:e27461 pubmed publisher
Vingtdeux V, Chandakkar P, Zhao H, d Abramo C, Davies P, Marambaud P. Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-? peptide degradation. FASEB J. 2011;25:219-31 pubmed publisher
product information
Antigen :
beta-Amyloid 1-40
Apps. Abbrev. :
IHC-P, Dot Blot, ELISA
Cat # :
805401
Clone :
11A50-B10
Item :
Purified (azide-free) anti-β-Amyloid, 1-40
Isotype :
Mouse IgG1, κ
Other Names :
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
Size :
200 μL
Price (USD) :
528 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PUREAF
Application Notes :
Clone 11A50-B10 is reactive to the C-terminus of beta amyloid and is specific for the isoform ending at the 40th amino acid.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA