HRP anti-Alpha-I Spectrin | BioLegend 803105 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

HRP anti-Alpha-I Spectrin

catalog :

803105

quantity :

25 μg

price :

153 USD

clonality :

monoclonal

host :

mouse

conjugate :

HRP

clone name :

17C7

reactivity :

human, mouse, rat

application :

western blot

citations: 1

Reference
Yang J, Wang Z, Cai H, Yuan L, Hu M, Wu M, et al. Sex Differences in Neuropathology and Cognitive Behavior in APP/PS1/tau Triple-Transgenic Mouse Model of Alzheimer's Disease. Neurosci Bull. 2018;34:736-746 pubmed publisher

product information

Antigen :

alpha-I Spectrin

Apps. Abbrev. :

Cat # :

803105

Clone :

17C7

Item :

HRP anti-Alpha-I Spectrin

Isotype :

Mouse IgG1, κ

Other Names :

EL2, SPTA1, Spectrin alpha chain, erythrocyte, alpha-I spectrin, erythroid alpha-spectrin

Size :

25 μg

Price (USD) :

153 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

HRP

Immunogen :

Clone 17C7 is developed against the alpha I spectrin SH3 domain (Xu et al ., 2000) 2 .

Application Notes :

This antibody is effective in Western Blotting (WB). Additional reported applications include immunocytochemistry^1, 2.Clone 17C7 is a specific marker for human, rat and mouse alpha I spectrin. It reacts with erythroid spectrin in red blood cells and in cerebellum. It does not crossreact with alpha II (nonerythroid) spectrin SH3 domain or recombinant human fodrin SH3 domain. In cerebellar cell cultures, clone 17C7 labels cell bodies consistent with localization of erythroid spectrin. In NIH 3T3 cells, clone 17C7 reacts with a 280 kDa protein which is a candidate marker of endocytic vesicles called macropinosomes^1, 2.This antibody was developed against a recombinant alpha I spectrin (erythroid spectrin) SH3 domain.;