Purified (azide-free) Anti-Alpha-I Spectrin | BioLegend 803101 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified (azide-free) Anti-Alpha-I Spectrin

catalog :

803101

quantity :

200 μL

price :

581 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

17C7

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; loading ...; fig 5i western blot; mouse; loading ...; fig 5e	Lubbers E, Murphy N, Musa H, Huang C, Gupta R, Price M, et al. Defining new mechanistic roles for αII spectrin in cardiac function. J Biol Chem. 2019;294:9576-9591 pubmed publisher
	Vaquero M, Cuesta S, Anerillas C, Altés G, Ribera J, Basson M, et al. Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine. J Am Soc Nephrol. 2019;30:1398-1411 pubmed publisher

product information

Antigen :

alpha-I Spectrin

Apps. Abbrev. :

WB, ICC

Cat # :

803101

Clone :

17C7

Item :

Purified (azide-free) Anti-Alpha-I Spectrin

Isotype :

Mouse IgG1, κ

Other Names :

EL2, SPTA1, Spectrin alpha chain, erythrocyte, alpha-I spectrin, erythroid alpha-spectrin

Size :

200 μL

Price (USD) :

581 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PUREAF

Immunogen :

Recombinant α spectrin SH3 domain

Application Notes :

This antibody is effective in Western Blotting (WB). Additional reported applications include immunocytochemistry^1, 2.Clone 17C7 is a specific marker for human, rat and mouse alpha I spectrin. It reacts with erythroid spectrin in red blood cells and in cerebellum. It does not crossreact with alpha II (nonerythroid) spectrin SH3 domain or recombinant human fodrin SH3 domain. In cerebellar cell cultures, clone 17C7 labels cell bodies consistent with localization of erythroid spectrin. In NIH 3T3 cells, clone 17C7 reacts with a 280 kDa protein which is a candidate marker of endocytic vesicles called macropinosomes^1, 2.This antibody was developed against a recombinant alpha I spectrin (erythroid spectrin) SH3 domain.;

more info or order :

BioLegend product webpage