Alexa Fluor® 647 anti-β-Amyloid, 1-16 | BioLegend 803020 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 647 anti-β-Amyloid, 1-16

catalog :

803020

quantity :

25 μg

price :

129 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

6.00E+10

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 6c immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1a	Zhao P, Xu Y, Jiang L, Fan X, Ku Z, Li L, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Mol Neurodegener. 2022;17:44 pubmed publisher
western blot; human; 1:1000; loading ...; fig s4b	Marengo L, Armbrust F, Schoenherr C, Storck S, Schmitt U, Zampar S, et al. Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease. Cell Mol Life Sci. 2022;79:168 pubmed publisher
ELISA; mouse	Tournissac M, Vu T, Vrabic N, Hozer C, Tremblay C, Mélançon K, et al. Repurposing beta-3 adrenergic receptor agonists for Alzheimer's disease: beneficial effects in a mouse model. Alzheimers Res Ther. 2021;13:103 pubmed publisher
immunohistochemistry - paraffin section; human; 1:2500; loading ...; fig 4a	Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed publisher
	Rajani R, Ellingford R, Hellmuth M, Harris S, Taso O, Graykowski D, et al. Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease. PLoS Biol. 2024;22:e3002727 pubmed publisher
	Hung C, Fertan E, Livesey F, Klenerman D, Patani R. APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease. Brain. 2024;147:2325-2333 pubmed publisher
	Braun D, Frazier H, Davis V, Coleman M, Rogers C, Van Eldik L. Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology. PLoS ONE. 2023;18:e0286495 pubmed publisher
	Emin D, Zhang Y, Lobanova E, Miller A, Li X, Xia Z, et al. Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease. Nat Commun. 2022;13:5512 pubmed publisher
	Pan J, Sun D, Lee D, Xiong L, Ren X, Guo H, et al. Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence. Commun Biol. 2021;4:1326 pubmed publisher
	McAlpine C, Park J, Griciuc A, Kim E, Choi S, Iwamoto Y, et al. Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature. 2021;595:701-706 pubmed publisher
	Braun D, Dimayuga E, Morganti J, Van Eldik L. Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer's disease. J Neuroinflammation. 2020;17:274 pubmed publisher

product information

Antigen :

beta-Amyloid 1-16

Apps. Abbrev. :

IHC-P

Cat # :

803020

Clone :

6.00E+10

Item :

Alexa Fluor® 647 anti-β-Amyloid, 1-16

Isotype :

Mouse IgG1, κ

Other Names :

AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein

Size :

25 μg

Price (USD) :

129 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A647

Application Notes :

This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS).This antibody clone has been reported for use in immunohistochemistry of free-floating sections^2,13.;

more info or order :

BioLegend product webpage