product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-MAP2
catalog :
801801
quantity :
100 μL
price :
258 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SMI 52
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 4e
  • immunohistochemistry; rat; 1:1000; loading ...; fig 4b
Rahman A, Weber J, Labin E, Lai C, Prieto A. Developmental expression of Neuregulin-3 in the rat central nervous system. J Comp Neurol. 2019;527:797-817 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6h
Shi Y, Ping Y, Zhou W, He Z, Chen C, Bian B, et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017;8:15080 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig st1
Ku T, Swaney J, Park J, Albanese A, Murray E, Cho J, et al. Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues. Nat Biotechnol. 2016;34:973-81 pubmed publisher
  • immunocytochemistry; human
Lu B, Palacino J. A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration. FASEB J. 2013;27:1820-9 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500
Dudanova I, Tabuchi K, Rohlmann A, Sudhof T, Missler M. Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation. J Comp Neurol. 2007;502:261-74 pubmed
de Leeuw V, van Oostrom C, Imholz S, Piersma A, Hessel E, Dollé M. Going Back and Forth: Episomal Vector Reprogramming of Peripheral Blood Mononuclear Cells to Induced Pluripotent Stem Cells and Subsequent Differentiation into Cardiomyocytes and Neuron-Astrocyte Co-cultures. Cell Reprogram. 2020;22:300-310 pubmed publisher
Wei W, Wang Y, Liu Y, Dai C, Tung Y, Liu F, et al. Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice. Alzheimers Res Ther. 2020;12:102 pubmed publisher
DeGiosio R, Kelly R, DeDionisio A, Newman J, Fish K, Sampson A, et al. MAP2 immunoreactivity deficit is conserved across the cerebral cortex within individuals with schizophrenia. NPJ Schizophr. 2019;5:13 pubmed publisher
McKinney B, MacDonald M, Newman J, Shelton M, DeGiosio R, Kelly R, et al. Density of small dendritic spines and microtubule-associated-protein-2 immunoreactivity in the primary auditory cortex of subjects with schizophrenia. Neuropsychopharmacology. 2019;44:1055-1061 pubmed publisher
Stern A, Ghura S, Gannon P, Akay Espinoza C, Phan J, Yee A, et al. BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism. J Neurosci. 2018;38:4288-4300 pubmed publisher
Wang X, Blanchard J, Grundke Iqbal I, Iqbal K. Memantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive Impairment. PLoS ONE. 2015;10:e0145441 pubmed publisher
Gensel J, Nakamura S, Guan Z, Van Rooijen N, Ankeny D, Popovich P. Macrophages promote axon regeneration with concurrent neurotoxicity. J Neurosci. 2009;29:3956-68 pubmed publisher
Hoover C, Hilgenberg L, Smith M. The COOH-terminal domain of agrin signals via a synaptic receptor in central nervous system neurons. J Cell Biol. 2003;161:923-32 pubmed
product information
Antigen :
MAP2
Apps. Abbrev. :
IHC-P, ICC, ELISA, Western Blotting
Cat # :
801801
Clone :
SMI 52
Item :
Purified (azide-free) anti-MAP2
Isotype :
Mouse IgG1, κ
Other Names :
Microtubule-associated protein 2, MAP-2
Size :
100 μL
Price (USD) :
258 USD
Reactivity :
Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PUREAF
Immunogen :
This monoclonal antibody was raised against Microtubule-Associated Protein 2 (MAP2).
Application Notes :
Additional reported applications (for relevant formats) include: immunocytochemistry 5,6 , ELISA 7 , and WB 1,5 . SMI 52 reacts with microtubule-associated protein 2 (MAP2). This antibody reacts with most mammalian species and with frog tissue. SMI 52 recognizes neuronal cell bodies and dendrites in tissue sections and cell cultures. In immunoblots of brain cytoskeletal preparations, SMI 52 reacts with MAP2a and b, and also with a doublet at 68 kD that may represent MAP2c.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA