Alexa Fluor® 647 anti-β-Amyloid, 17-24 | BioLegend 800717 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 647 anti-β-Amyloid, 17-24

catalog :

800717

quantity :

25 μg

price :

129 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

4G8

reactivity :

human, mouse

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - free floating section; human; 1:5000; loading ...	Braak H, Del Tredici K. From the Entorhinal Region via the Prosubiculum to the Dentate Fascia: Alzheimer Disease-Related Neurofibrillary Changes in the Temporal Allocortex. J Neuropathol Exp Neurol. 2020;79:163-175 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1b	Smith R, Pawlik D, Nilsson C, Englund E, Hansson O. [18F]Flortaucipir distinguishes Alzheimer's disease from progressive supranuclear palsy pathology in a mixed-pathology case. Acta Neuropathol. 2020;139:411-413 pubmed publisher
immunohistochemistry; human; 1:9,000; loading ...; tbl 2	Yu L, Boyle P, Dawe R, Bennett D, Arfanakis K, Schneider J. Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons. Neurology. 2020;94:e142-e152 pubmed publisher
	You Y, Zhang Z, Sultana N, Ericsson M, Martens Y, Sun M, et al. ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids. Sci Adv. 2023;9:eadi3647 pubmed publisher
	Zhang B, Miao T, Shen X, Bao L, Zhang C, Yan C, et al. EB virus-induced ATR activation accelerates nasopharyngeal carcinoma growth via M2-type macrophages polarization. Cell Death Dis. 2020;11:742 pubmed publisher
	Guo J, Muse E, Christians A, Swanson S, Davila E. An Anticancer Drug Cocktail of Three Kinase Inhibitors Improved Response to a Dendritic Cell-Based Cancer Vaccine. Cancer Immunol Res. 2019;7:1523-1534 pubmed publisher
	Hatami A, Monjazeb S, Glabe C. The Anti-Amyloid-Î² Monoclonal Antibody 4G8 Recognizes a Generic Sequence-Independent Epitope Associated with Î±-Synuclein and Islet Amyloid Polypeptide Amyloid Fibrils. J Alzheimers Dis. 2016;50:517-25 pubmed publisher
	Forny Germano L, Lyra e Silva N, Batista A, Brito Moreira J, Gralle M, Boehnke S, et al. Alzheimer's disease-like pathology induced by amyloid-Î² oligomers in nonhuman primates. J Neurosci. 2014;34:13629-43 pubmed publisher

product information

Antigen :

beta-Amyloid 17-24

Apps. Abbrev. :

IHC-P

Cat # :

800717

Clone :

4G8

Item :

Alexa Fluor® 647 anti-β-Amyloid, 17-24

Isotype :

Mouse IgG2b, κ

Other Names :

AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein

Size :

25 μg

Price (USD) :

129 USD

Reactivity :

Human, Mouse

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A647

Application Notes :

This antibody is reactive to amino acid residues 17-24 of ß amyloid. The epitope lies within amino acids 18-22 of ß amyloid (VFFAE). 4G8 ß-amyloid antibody reacts to abnormally processed isoforms, as well as precursor forms.This antibody clone has been reported for use on IHC of free-floating sections in PBS containing 1% Triton incubated with 0.1 m citrate buffer (4).Additional reported applications (for the relevant formats) include: immunohistochemical staining on frozen tissue sections (IHC-F) and immunocytochemistry (ICC);

more info or order :

BioLegend product webpage