Recombinant MU B7-H1 (PD-L1, CD274)-Fc Chimera (CF) | BioLegend 758206 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

protein

product name :

Recombinant MU B7-H1 (PD-L1, CD274)-Fc Chimera (CF)

catalog :

758206

quantity :

100 μg

price :

229 USD

more info or order :

BioLegend product webpage

citations: 6

Reference
Smith B, Tinkey R, Brock O, Mariam A, Habean M, Dutta R, et al. Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1. J Neuroinflammation. 2023;20:234 pubmed publisher
Pereira J, Lanzar Z, Clark J, Hart A, Douglas B, Shallberg L, et al. PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis. Front Immunol. 2023;14:997376 pubmed publisher
Wang H, Khattar V, Hensel J, Ashton R, Lu Y, Sorace A, et al. Systemic Checkpoint Blockade by PD-L1 Single-Chain Antibody Confers Potent Antitumor Immunity and Long-term Survival. Mol Cancer Ther. 2022;21:1710-1721 pubmed publisher
Cheng B, Ding K, Chen P, Ji J, Luo T, Guo X, et al. Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer. Cancer Commun (Lond). 2022;42:17-36 pubmed publisher
Liao Y, Wu S, Huang Y, Lo P, Chan T, Chen C, et al. NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities. Front Immunol. 2021;12:743030 pubmed publisher
Mitchell L, Yagiz K, Hofacre A, Viaud S, Munday A, Espinoza F, et al. PD-L1 checkpoint blockade delivered by retroviral replicating vector confers anti-tumor efficacy in murine tumor models. Oncotarget. 2019;10:2252-2269 pubmed publisher

product information

Antigen :

B7-H1

Apps. Abbrev. :

Cat # :

758206

Item :

Recombinant MU B7-H1 (PD-L1, CD274)-Fc Chimera (CF)

Other Names :

CD274, Programmed cell death 1 ligand 1 (PD-L1), B7 homolog 1 (B7h1)

Size :

100 μg

Price (USD) :

229 USD

Reactivity :

Mouse

Host :

ADD EXPRESSION SYSTEM HERE

Conjugate/Tag/Label :

RECOM

Application Notes :

BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal or better stability and shelf-life compared to commercially available lyophilized proteins after reconstitution. Our liquid proteins are verified in-house to maintain activity after shipping on blue ice and are backed by our 100% satisfaction guarantee. If you have any concerns, contact us at tech@biolegend.com.;

more info or order :

BioLegend product webpage