product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse Ki-67
catalog :
652402
quantity :
100 μg
price :
206 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
16A8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
more info or order :
citations: 57
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s5a, s5e
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
  • other; mouse; loading ...
Van Maldegem F, Valand K, Cole M, Patel H, Angelova M, Rana S, et al. Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry. Nat Commun. 2021;12:5906 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s13b
Wang Z, He L, Li W, Xu C, Zhang J, Wang D, et al. GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma. J Immunother Cancer. 2021;9: pubmed publisher
  • flow cytometry; mouse; loading ...
Forman R, Logunova L, Smith H, Wemyss K, Mair I, Boon L, et al. Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages. PLoS Pathog. 2021;17:e1009768 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Li J, Xu J, Li Z. Obatoclax, the pan-Bcl-2 inhibitor sensitizes hepatocellular carcinoma cells to promote the anti-tumor efficacy in combination with immune checkpoint blockade. Transl Oncol. 2021;14:101116 pubmed publisher
  • flow cytometry; mouse; fig s4c
Wei J, Long L, Zheng W, Dhungana Y, Lim S, Guy C, et al. Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Nature. 2019;576:471-476 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5c
Papaioannou E, Yanez D, Ross S, Lau C, Solanki A, Chawda M, et al. Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation. J Clin Invest. 2019;129:3153-3170 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3f
Di Pilato M, Kim E, Cadilha B, Prüßmann J, Nasrallah M, Seruggia D, et al. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. 2019;570:112-116 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1f
Shi H, Han X, Sun Y, Shang C, Wei M, Ba X, et al. Chemokine (C-X-C motif) ligand 1 and CXCL2 produced by tumor promote the generation of monocytic myeloid-derived suppressor cells. Cancer Sci. 2018;109:3826-3839 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5b
Vendetti F, Karukonda P, Clump D, Teo T, Lalonde R, Nugent K, et al. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. J Clin Invest. 2018;128:3926-3940 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2i
Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1b
Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Cribbs A, Hookway E, Wells G, Lindow M, Obad S, Oerum H, et al. Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells. J Biol Chem. 2018;293:2422-2437 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Mailer R, Gisterå A, Polyzos K, Ketelhuth D, Hansson G. Hypercholesterolemia Enhances T Cell Receptor Signaling and Increases the Regulatory T Cell Population. Sci Rep. 2017;7:15655 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Billerbeck E, Wolfisberg R, Fahnøe U, Xiao J, Quirk C, Luna J, et al. Mouse models of acute and chronic hepacivirus infection. Science. 2017;357:204-208 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8c
Olivares O, Mayers J, Gouirand V, Torrence M, Gicquel T, Borge L, et al. Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions. Nat Commun. 2017;8:16031 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2i
Sindhava V, Oropallo M, Moody K, Naradikian M, Higdon L, Zhou L, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017;127:1651-1663 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Subbarayal B, Chauhan S, Di Zazzo A, Dana R. IL-17 Augments B Cell Activation in Ocular Surface Autoimmunity. J Immunol. 2016;197:3464-3470 pubmed
  • immunohistochemistry; mouse; fig 1a
Otsuka K, Suzuki K. Differences in Radiation Dose Response between Small and Large Intestinal Crypts. Radiat Res. 2016;186:302-14 pubmed publisher
  • flow cytometry; human; loading ...; fig s3
Ruibal P, Oestereich L, Lüdtke A, Becker Ziaja B, Wozniak D, Kerber R, et al. Unique human immune signature of Ebola virus disease in Guinea. Nature. 2016;533:100-4 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 3
Thakur A, Nigri J, Lac S, Leca J, Bressy C, Berthezene P, et al. TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma. Cell Death Differ. 2016;23:1358-70 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Foks A, Engelbertsen D, Kuperwaser F, Alberts Grill N, Gonen A, Witztum J, et al. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016;36:456-65 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 3
von Moltke J, Ji M, Liang H, Locksley R. Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit. Nature. 2016;529:221-5 pubmed publisher
  • flow cytometry; mouse; fig 2
Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig s3
Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, et al. Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma. Proc Natl Acad Sci U S A. 2015;112:2473-8 pubmed publisher
  • immunohistochemistry; human; fig 8
Medina Reyes E, Déciga Alcaraz A, Freyre Fonseca V, Delgado Buenrostro N, Flores Flores J, Gutiérrez López G, et al. Titanium dioxide nanoparticles induce an adaptive inflammatory response and invasion and proliferation of lung epithelial cells in chorioallantoic membrane. Environ Res. 2015;136:424-34 pubmed publisher
  • flow cytometry; mouse
Johannesson B, Sattler S, Semenova E, Pastore S, Kennedy Lydon T, Sampson R, et al. Insulin-like growth factor-1 induces regulatory T cell-mediated suppression of allergic contact dermatitis in mice. Dis Model Mech. 2014;7:977-85 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Sousa Victor P, Gutarra S, García Prat L, Rodriguez Ubreva J, Ortet L, Ruiz Bonilla V, et al. Geriatric muscle stem cells switch reversible quiescence into senescence. Nature. 2014;506:316-21 pubmed publisher
Horiuchi S, Oishi K, Carrau L, Frere J, Møller R, Panis M, et al. Immune memory from SARS-CoV-2 infection in hamsters provides variant-independent protection but still allows virus transmission. Sci Immunol. 2021;6:eabm3131 pubmed publisher
Villarreal Ponce A, Tiruneh M, Lee J, Guerrero Juarez C, Kuhn J, David J, et al. Keratinocyte-Macrophage Crosstalk by the Nrf2/Ccl2/EGF Signaling Axis Orchestrates Tissue Repair. Cell Rep. 2020;33:108417 pubmed publisher
Matsumori T, Kodama Y, Takai A, Shiokawa M, Nishikawa Y, Matsumoto T, et al. Hes1 Is Essential in Proliferating Ductal Cell-Mediated Development of Intrahepatic Cholangiocarcinoma. Cancer Res. 2020;80:5305-5316 pubmed publisher
Hollinshead K, Parker S, Eapen V, Encarnación Rosado J, Sohn A, Oncu T, et al. Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer. Cell Rep. 2020;33:108231 pubmed publisher
Minamide K, Sato T, Nakanishi Y, Ohno H, Kato T, Asano J, et al. IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon. Sci Rep. 2020;10:14639 pubmed publisher
Clark K, Yau J, Bloom A, Wang J, Venzon D, Suzuki M, et al. Structure-Function Implications of the Ability of Monoclonal Antibodies Against α-Galactosylceramide-CD1d Complex to Recognize β-Mannosylceramide Presentation by CD1d. Front Immunol. 2019;10:2355 pubmed publisher
Matsumoto Y, Nakanishi Y, Yoshioka T, Yamaga Y, Masuda T, Fukunaga Y, et al. Epithelial EP4 plays an essential role in maintaining homeostasis in colon. Sci Rep. 2019;9:15244 pubmed publisher
Wang G, Zhao H, Zheng B, Li D, Yuan Y, Han Q, et al. TLR2 Promotes Monocyte/Macrophage Recruitment Into the Liver and Microabscess Formation to Limit the Spread of Listeria Monocytogenes. Front Immunol. 2019;10:1388 pubmed publisher
Lee J, Lee H, Kim S, Cho G, Woodruff T. Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice. Yonsei Med J. 2019;60:667-678 pubmed publisher
Arnold I, Zhang X, Artola Borán M, Fallegger A, Sander P, Johansen P, et al. BATF3-dependent dendritic cells drive both effector and regulatory T-cell responses in bacterially infected tissues. PLoS Pathog. 2019;15:e1007866 pubmed publisher
Brown E, Ke X, Hitchcock D, Jeanfavre S, Avila Pacheco J, Nakata T, et al. Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis. Cell Host Microbe. 2019;25:668-680.e7 pubmed publisher
Heimesaat M, Escher U, Grunau A, Kuhl A, Bereswill S. Multidrug-Resistant Pseudomonas aeruginosa Accelerate Intestinal, Extra-Intestinal, and Systemic Inflammatory Responses in Human Microbiota-Associated Mice With Subacute Ileitis. Front Immunol. 2019;10:49 pubmed publisher
Men L, Sun J, Ren D. Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells. Cell Physiol Biochem. 2018;51:2185-2197 pubmed publisher
Zhao L, He R, Long H, Guo B, Jia Q, Qin D, et al. Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells. Nat Med. 2018;24:1536-1544 pubmed publisher
Zingg D, Debbache J, Peña Hernández R, Antunes A, Schaefer S, Cheng P, et al. EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation. Cancer Cell. 2018;34:69-84.e14 pubmed publisher
Heimesaat M, Escher U, Grunau A, Fiebiger U, Bereswill S. Peroral Low-Dose Toxoplasma gondii Infection of Human Microbiota-Associated Mice - A Subacute Ileitis Model to Unravel Pathogen-Host Interactions. Eur J Microbiol Immunol (Bp). 2018;8:53-61 pubmed publisher
Yuan C, Liang R, Liu Z, Li Y, Luo X, Ye J, et al. Bone morphogenetic protein and activin membrane-bound inhibitor overexpression inhibits gastric tumor cell invasion via the transforming growth factor-β/epithelial-mesenchymal transition signaling pathway. Exp Ther Med. 2018;15:5422-5430 pubmed publisher
Klose A, Liu W, Paris N, Forman S, Krolewski J, Nastiuk K, et al. Castration induces satellite cell activation that contributes to skeletal muscle maintenance. JCSM Rapid Commun. 2018;1: pubmed
Stelekati E, Chen Z, Manne S, Kurachi M, Ali M, Lewy K, et al. Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155. Cell Rep. 2018;23:2142-2156 pubmed publisher
von Klitzing E, Ekmekciu I, Kühl A, Bereswill S, Heimesaat M. Multidrug-resistant Pseudomonas aeruginosa aggravates inflammatory responses in murine chronic colitis. Sci Rep. 2018;8:6685 pubmed publisher
Chen M, Liang S, Qin X, Zhang L, Qiu L, Chen S, et al. Prenatal exposure to diesel exhaust PM2.5 causes offspring β cell dysfunction in adulthood. Am J Physiol Endocrinol Metab. 2018;315:E72-E80 pubmed publisher
Herring C, Banerjee A, McKinley E, Simmons A, Ping J, Roland J, et al. Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut. Cell Syst. 2018;6:37-51.e9 pubmed publisher
Yang S, Li L, Xie Y, Yao Y, Gao C, Liao L, et al. IFN-?-STAT1-iNOS Induces Myeloid Progenitors to Acquire Immunosuppressive Activity. Front Immunol. 2017;8:1192 pubmed publisher
Xu L, Zhang W, Zeng L, Jin J. Rehmannia glutinosa polysaccharide induced an anti-cancer effect by activating natural killer cells. Int J Biol Macromol. 2017;105:680-685 pubmed publisher
Halim D, Wilson M, Oliver D, Brosens E, Verheij J, Han Y, et al. Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice. Proc Natl Acad Sci U S A. 2017;114:E2739-E2747 pubmed publisher
Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, et al. Protein kinase C? controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen. J Allergy Clin Immunol. 2017;139:1650-1666 pubmed publisher
Wang C, Chen S, Yeo S, Karsli Uzunbas G, White E, Mizushima N, et al. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. J Cell Biol. 2016;212:545-60 pubmed publisher
Hennchen M, Stubbusch J, Abarchan El Makhfi I, Krämer M, Deller T, Pierre Eugene C, et al. Lin28B and Let-7 in the Control of Sympathetic Neurogenesis and Neuroblastoma Development. J Neurosci. 2015;35:16531-44 pubmed publisher
Hallam D, Wan T, Saretzki G. Dietary restriction mitigates age-related accumulation of DNA damage, but not all changes in mouse corneal epithelium. Exp Gerontol. 2015;67:72-9 pubmed publisher
product information
Antigen :
Ki-67
Apps. Abbrev. :
FC, WB, ICC, IHC-F
Cat # :
652402
Clone :
16A8
Item :
Purified anti-mouse Ki-67
Isotype :
Rat IgG2a, κ
Other Names :
KIA, proliferation-related Ki-67 antigen
Size :
100 μg
Price (USD) :
206 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
E. coli expressed partial mouse Ki-67 recombinant protein, 1816-2163 aa.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA