product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-HMGB1
catalog :
651402
quantity :
100 μg
price :
323 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3.00E+08
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section, blocking or activating experiments
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; loading ...; fig s5a
Narayanaswamy P, Tkachuk S, Haller H, Dumler I, Kiyan Y. CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling. Cell Death Dis. 2016;7:e2383 pubmed publisher
  • western blot; mouse; 1:500; fig 5
Cardoso F, Herz J, Fernandes A, Rocha J, Sepodes B, Brito M, et al. Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects. J Neuroinflammation. 2015;12:82 pubmed publisher
Hayashi K, Nikolos F, Lee Y, Jain A, Tsouko E, Gao H, et al. Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death. Nat Commun. 2020;11:6299 pubmed publisher
Zemskova M, McClain N, Niihori M, Varghese M, James J, Rafikov R, et al. Necrosis-Released HMGB1 (High Mobility Group Box 1) in the Progressive Pulmonary Arterial Hypertension Associated With Male Sex. Hypertension. 2020;76:1787-1799 pubmed publisher
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
Jeong J, Lee J, Lim J, Cho S, An S, Lee M, et al. Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE. Exp Mol Med. 2019;51:1-15 pubmed publisher
Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, et al. PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. Dev Cell. 2018;46:441-455.e8 pubmed publisher
de Mingo Pulido Á, Gardner A, Hiebler S, Soliman H, Rugo H, Krummel M, et al. TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. Cancer Cell. 2018;33:60-74.e6 pubmed publisher
product information
Antigen :
HMGB1
Apps. Abbrev. :
WB, ICC, IHC-P
Cat # :
651402
Clone :
3.00E+08
Item :
Purified anti-HMGB1
Isotype :
Mouse IgG2b, κ
Other Names :
High mobility group protein 1, High mobility group protein B1, Sulfoglucuronyl carbohydrate binding protein
Size :
100 μg
Price (USD) :
323 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Recombinant human HMGB1 with GST tag. A universal T cell epitope from a Mycobacterium tuberculosis antigen was introduced into the C-terminus of HMGB1 to increase the immunogenicity.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA