product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mMCP-8
catalog :
647401
quantity :
25 μg
price :
124 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
TUG8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - frozen section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 1e
Hiroyasu S, Zeglinski M, Zhao H, Pawluk M, Turner C, Kasprick A, et al. Granzyme B inhibition reduces disease severity in autoimmune blistering diseases. Nat Commun. 2021;12:302 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3e
Hidaka T, Ogawa E, Kobayashi E, Suzuki T, Funayama R, Nagashima T, et al. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nat Immunol. 2017;18:64-73 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Schwartz C, Turqueti Neves A, Hartmann S, Yu P, Nimmerjahn F, Voehringer D. Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion. Proc Natl Acad Sci U S A. 2014;111:E5169-77 pubmed publisher
Pattabiraman G, Bell Cohn A, Murphy S, Mazur D, Schaeffer A, Thumbikat P. Mast cell function in prostate inflammation, fibrosis, and smooth muscle cell dysfunction. Am J Physiol Renal Physiol. 2021;321:F466-F479 pubmed publisher
Sicklinger F, Meyer I, Li X, Radtke D, Dicks S, Kornadt M, et al. Basophils balance healing after myocardial infarction via IL-4/IL-13. J Clin Invest. 2021;131: pubmed publisher
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
Webb L, Oyesola O, Früh S, Kamynina E, Still K, Patel R, et al. The Notch signaling pathway promotes basophil responses during helminth-induced type 2 inflammation. J Exp Med. 2019;216:1268-1279 pubmed publisher
Piliponsky A, Shubin N, Lahiri A, Truong P, Clauson M, Niino K, et al. Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice. Nat Immunol. 2019;20:129-140 pubmed publisher
Imai Y, Hosotani Y, Ishikawa H, Yasuda K, Nagai M, Jitsukawa O, et al. Expression of IL-33 in ocular surface epithelium induces atopic keratoconjunctivitis with activation of group 2 innate lymphoid cells in mice. Sci Rep. 2017;7:10053 pubmed publisher
De Monte L, Wörmann S, Brunetto E, Heltai S, Magliacane G, Reni M, et al. Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients. Cancer Res. 2016;76:1792-803 pubmed publisher
Schwartz C, Oeser K, Prazeres da Costa C, Layland L, Voehringer D. T cell-derived IL-4/IL-13 protects mice against fatal Schistosoma mansoni infection independently of basophils. J Immunol. 2014;193:3590-9 pubmed publisher
Morshed M, Hlushchuk R, Simon D, Walls A, Obata Ninomiya K, Karasuyama H, et al. NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol. 2014;192:5314-23 pubmed publisher
Uto Konomi A, Miyauchi K, Ozaki N, Motomura Y, Suzuki Y, Yoshimura A, et al. Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines. PLoS ONE. 2012;7:e40343 pubmed publisher
product information
Antigen :
mMCP-8
Apps. Abbrev. :
WB
Cat # :
647401
Clone :
TUG8
Item :
Purified anti-mMCP-8
Isotype :
Rat IgG2a, κ
Other Names :
Mouse Mast Cell Protease 8, Mcpt8
Size :
25 μg
Price (USD) :
124 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
Recombinant GST-mouse mMCP-8 fusion protein expressed in E.coli
Application Notes :
The optimal concentration should be determined by titration for each individual assay of interest.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA