product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-Syk
catalog :
646002
quantity :
100 μg
price :
265 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5F5
reactivity :
human, mouse
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig s1
Muro R, Nitta T, Nakano K, Okamura T, Takayanagi H, Suzuki H. γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program. J Clin Invest. 2018;128:415-426 pubmed publisher
  • immunoprecipitation; mouse; 4.4 ug/ml; fig 7
Nemeth T, Futosi K, Sitaru C, Ruland J, Mocsai A. Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo. Nat Commun. 2016;7:11004 pubmed publisher
  • flow cytometry; mouse; fig 3
Ackermann J, Nys J, Schweighoffer E, McCleary S, Smithers N, Tybulewicz V. Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival. J Immunol. 2015;194:4650-6 pubmed publisher
Pessoa Rodrigues C, Herman J, Herquel B, Valsecchi C, Stehle T, Grün D, et al. Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Sci Adv. 2020;6:eaaz4815 pubmed publisher
Viny A, Bowman R, Liu Y, Lavallée V, Eisman S, Xiao W, et al. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019;25:682-696.e8 pubmed publisher
Luchsinger L, Strikoudis A, Danzl N, Bush E, Finlayson M, Satwani P, et al. Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro. Cell Stem Cell. 2019;: pubmed publisher
Luo W, Weisel F, Shlomchik M. B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells. Immunity. 2018;48:313-326.e5 pubmed publisher
product information
Antigen :
Syk
Apps. Abbrev. :
WB, IP
Cat # :
646002
Clone :
5F5
Item :
Purified anti-Syk
Isotype :
Mouse IgG1, κ
Other Names :
Spleen tyrosine kinase, protein tyrosine kinase SYK
Size :
100 μg
Price (USD) :
265 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Mouse Syk peptide aa306-333
Application Notes :
This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes contact The Regents of the University of California.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA