product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-T-bet
catalog :
644811
quantity :
25 μg
price :
165 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
4B10
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 7b, s1a
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Demers K, Makedonas G, Buggert M, Eller M, Ratcliffe S, Goonetilleke N, et al. Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection. PLoS Pathog. 2016;12:e1005805 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2e
Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed publisher
Zhang M, Chong K, Chen Z, Guo H, Liu Y, Kang Y, et al. Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes. JCI Insight. 2023;8: pubmed publisher
McEvoy C, Murphy J, Zhang L, Clotet Freixas S, Mathews J, An J, et al. Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity. Nat Commun. 2022;13:7634 pubmed publisher
Wei H, Li Y, Guo Z, Ma X, Li Y, Wei X, et al. Comparison of dynamic changes in the peripheral CD8+ T cells function and differentiation in ESCC patients treated with radiotherapy combined with anti-PD-1 antibody or concurrent chemoradiotherapy. Front Immunol. 2022;13:1060695 pubmed publisher
Lin G, Zhang L, Yan Z, Jiang W, Wu B, Li D, et al. Identification of heterogeneous subsets of aortic interleukin-17A-expressing CD4+ T cells in atherosclerotic mice. Int J Immunopathol Pharmacol. 2022;36:3946320221117933 pubmed publisher
Li X, Dong L, Liu J, Wang C, Zhang Y, Mei Q, et al. Low-Dose Decitabine Augments the Activation and Anti-Tumor Immune Response of IFN-γ+ CD4+ T Cells Through Enhancing IκBα Degradation and NF-κB Activation. Front Cell Dev Biol. 2021;9:647713 pubmed publisher
Islas Vazquez L, Aguilar Cazares D, Galicia Velasco M, Rumbo Nava U, Meneses Flores M, Luna Rivero C, et al. IL-6, NLR, and SII Markers and Their Relation with Alterations in CD8+ T-Lymphocyte Subpopulations in Patients Treated for Lung Adenocarcinoma. Biology (Basel). 2020;9: pubmed publisher
Bhattacharya P, Ellegård R, Khalid M, Svanberg C, Govender M, Keita A, et al. Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells. elife. 2020;9: pubmed publisher
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
Naluyima P, Lal K, Costanzo M, Kijak G, Gonzalez V, Blom K, et al. Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity. J Immunol. 2019;203:2210-2221 pubmed publisher
Dayoub O, Le Lay S, Soleti R, Clere N, Hilairet G, Dubois S, et al. Estrogen receptor α/HDAC/NFAT axis for delphinidin effects on proliferation and differentiation of T lymphocytes from patients with cardiovascular risks. Sci Rep. 2017;7:9378 pubmed publisher
Ostadkarampour M, Müller M, Ockinger J, Kullberg S, Linden A, Eklund A, et al. Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function. PLoS ONE. 2016;11:e0164751 pubmed publisher
Hoffmann M, Pantazis N, Martin G, Hickling S, Hurst J, Meyerowitz J, et al. Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection. PLoS Pathog. 2016;12:e1005661 pubmed publisher
Okamoto Y, Hara T, Ebato T, Fukui T, Masuzawa T. Brazilian propolis ameliorates trinitrobenzene sulfonic acid-induced colitis in mice by inhibiting Th1 differentiation. Int Immunopharmacol. 2013;16:178-83 pubmed publisher
Smith C, Elhassen D, Gras S, Wynn K, Dasari V, Tellam J, et al. Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells. Blood. 2012;120:3237-45 pubmed publisher
Hsieh C, Chen C, Tsai C, Huang W, Tseng P, Lin Y, et al. Inhibiting glycogen synthase kinase-3 decreases 12-O-tetradecanoylphorbol-13-acetate-induced interferon-?-mediated skin inflammation. J Pharmacol Exp Ther. 2012;343:125-33 pubmed publisher
Blom L, Poulsen B, Jensen B, Hansen A, Poulsen L. IL-33 induces IL-9 production in human CD4+ T cells and basophils. PLoS ONE. 2011;6:e21695 pubmed publisher
product information
Antigen :
T-bet
Apps. Abbrev. :
ICFC
Cat # :
644811
Clone :
4B10
Item :
FITC anti-T-bet
Isotype :
Mouse IgG1, κ
Other Names :
T-box expressed in T cells, T box 21, TBLYM
Size :
25 μg
Price (USD) :
165 USD
Reactivity :
Human, Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA