product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-T-bet
catalog :
644805
quantity :
25 μg
price :
200 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B10
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s2b
Shi Z, Takeuchi T, Nakanishi Y, Kato T, Beck K, Nagata R, et al. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Front Immunol. 2022;13:903459 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7b, s1a
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 5b
Minns D, Smith K, Alessandrini V, Hardisty G, Melrose L, Jackson Jones L, et al. The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation. Nat Commun. 2021;12:1285 pubmed publisher
Nunes Santos C, Kuehn H, Boast B, Hwang S, Kuhns D, Stoddard J, et al. Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling. Nat Commun. 2023;14:3708 pubmed publisher
Read K, Jones D, Pokhrel S, Hales E, Varkey A, Tuazon J, et al. Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity. Nat Commun. 2023;14:1652 pubmed publisher
Zhu X, Li Q, George V, Spanoudis C, Gilkes C, Shrestha N, et al. A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice. Front Immunol. 2023;14:1114802 pubmed publisher
Glaubitz J, Wilden A, Frost F, Ameling S, Homuth G, Mazloum H, et al. Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis. Gut. 2023;72:1355-1369 pubmed publisher
Wang W, Wu S, Cen Z, Zhang Y, Chen Y, Huang Y, et al. Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy. Cell Rep. 2022;41:111582 pubmed publisher
Webb E, Moreno Vincente J, Easton A, Lanati S, Taylor M, James S, et al. Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma. iScience. 2022;25:104995 pubmed publisher
Glaubitz J, Wilden A, Golchert J, Homuth G, V xf6 lker U, Br xf6 ker B, et al. In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response. Nat Commun. 2022;13:4502 pubmed publisher
Zander R, Kasmani M, Chen Y, Topchyan P, Shen J, Zheng S, et al. Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection. Immunity. 2022;55:475-493.e5 pubmed publisher
Nabatanzi R, Bayigga L, Cose S, Canderan G, Rowland Jones S, Joloba M, et al. Innate lymphoid cell dysfunction during long-term suppressive antiretroviral therapy in an African cohort. BMC Immunol. 2021;22:59 pubmed publisher
Chen Y, Zander R, Wu X, Schauder D, Kasmani M, Shen J, et al. BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection. Nat Immunol. 2021;22:996-1007 pubmed publisher
Huanosta Murillo E, Alc xe1 ntara Hern xe1 ndez M, Hern xe1 ndez Rico B, Victoria Acosta G, Miranda Cruz P, Dom xed nguez G xf3 mez M, et al. NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression. Front Immunol. 2021;12:668369 pubmed publisher
Sutton H, Aye R, Idris A, Vistein R, Nduati E, Kai O, et al. Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans. Cell Rep. 2021;34:108684 pubmed publisher
Xu W, Snell L, Guo M, Boukhaled G, Macleod B, Li M, et al. Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection. Immunity. 2021;54:526-541.e7 pubmed publisher
Rustenhoven J, Drieu A, Mamuladze T, de Lima K, Dykstra T, Wall M, et al. Functional characterization of the dural sinuses as a neuroimmune interface. Cell. 2021;184:1000-1016.e27 pubmed publisher
Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, et al. Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity. Immunity. 2020;52:1075-1087.e8 pubmed publisher
Zander R, SCHAUDER D, Xin G, Nguyen C, Wu X, ZAJAC A, et al. CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. Immunity. 2019;51:1028-1042.e4 pubmed publisher
Marro B, Zak J, Zavareh R, Teijaro J, Lairson L, Oldstone M. Discovery of Small Molecules for the Reversal of T Cell Exhaustion. Cell Rep. 2019;29:3293-3302.e3 pubmed publisher
Chun E, Lavoie S, Fonseca Pereira D, Bae S, Michaud M, Hoveyda H, et al. Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity. Immunity. 2019;51:871-884.e6 pubmed publisher
Frasca D, Diaz A, Romero M, Thaller S, Blomberg B. Metabolic requirements of human pro-inflammatory B cells in aging and obesity. PLoS ONE. 2019;14:e0219545 pubmed publisher
Lavoie S, Conway K, Lassen K, Jijon H, Pan H, Chun E, et al. The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response. elife. 2019;8: pubmed publisher
Liu Q, Ma W, Yang J, Zhao Z, Yan K, Yao Y, et al. The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8+ T Cells but Promotes Colitis via CD4+ T Cells. Front Immunol. 2018;9:1090 pubmed publisher
Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, et al. Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania. PLoS Negl Trop Dis. 2017;11:e0005817 pubmed publisher
Hurton L, Singh H, Najjar A, Switzer K, Mi T, Maiti S, et al. Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells. Proc Natl Acad Sci U S A. 2016;113:E7788-E7797 pubmed
product information
Antigen :
T-bet
Apps. Abbrev. :
ICFC
Cat # :
644805
Clone :
4B10
Item :
PerCP/Cyanine5.5 anti-T-bet
Isotype :
Mouse IgG1, κ
Other Names :
T-box expressed in T cells, T box 21, TBLYM
Size :
25 μg
Price (USD) :
200 USD
Reactivity :
Human, Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PERCP_CYANINE5.5
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA