product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-Syk
catalog :
644301
quantity :
25 μg
price :
118 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4D10.2
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2d
Pugh J, Nemat Gorgani N, Norman P, Guethlein L, Parham P. Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage. J Immunol. 2018;200:1146-1158 pubmed publisher
  • flow cytometry; human; loading ...; fig s7a
Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed publisher
Chen L, PATIL S, Barbon J, Waire J, Laroux S, McCarthy D, et al. Agonistic anti-DCIR antibody inhibits ITAM-mediated inflammatory signaling and promotes immune resolution. JCI Insight. 2024;9: pubmed publisher
Ghosh S, Di Bartolo V, Tubul L, Shimoni E, Kartvelishvily E, Dadosh T, et al. ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation. Cell Rep. 2020;30:3434-3447.e6 pubmed publisher
Bauer B, Wotapek T, Zöller T, Rutkowski E, Steinle A. The Activating C-type Lectin-like Receptor NKp65 Signals through a Hemi-immunoreceptor Tyrosine-based Activation Motif (hemITAM) and Spleen Tyrosine Kinase (Syk). J Biol Chem. 2017;292:3213-3223 pubmed publisher
Foster G, Xu L, Chidambaram A, Soderberg S, Armstrong E, Wu H, et al. CD11c/CD18 Signals Very Late Antigen-4 Activation To Initiate Foamy Monocyte Recruitment during the Onset of Hypercholesterolemia. J Immunol. 2015;195:5380-92 pubmed publisher
product information
Antigen :
Syk
Apps. Abbrev. :
WB, IP, ICFC, IHC-P
Cat # :
644301
Clone :
4D10.2
Item :
Purified anti-Syk
Isotype :
Mouse IgG2a, κ
Other Names :
Spleen tyrosine kinase, protein tyrosine kinase SYK
Size :
25 μg
Price (USD) :
118 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Human Syk peptide aa314-339
Application Notes :
This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact The Regents of the University of California.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA