product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-CD247 (TCRζ, CD3ζ)
catalog :
644101
quantity :
25 μg
price :
118 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6B10.2
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
citations: 6
Reference
Lah S, Kim S, Kang I, Kim H, Hupperetz C, Jung H, et al. Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus. J Immunother Cancer. 2023;11: pubmed publisher
Wang X, Zhang H, Wang Y, Bramasole L, Guo K, Mourtada F, et al. DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity. EMBO J. 2023;42:e110597 pubmed publisher
Ye Z, Shen Y, Jin K, Qiu J, Hu B, Jadhav R, et al. Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation. Nat Commun. 2021;12:907 pubmed publisher
Ghosh S, Di Bartolo V, Tubul L, Shimoni E, Kartvelishvily E, Dadosh T, et al. ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation. Cell Rep. 2020;30:3434-3447.e6 pubmed publisher
Hwang I, Zhang T, Scott J, Kim A, Lee T, Kakarla T, et al. Identification of human NK cells that are deficient for signaling adaptor FcR? and specialized for antibody-dependent immune functions. Int Immunol. 2012;24:793-802 pubmed publisher
Mao H, Tu W, Liu Y, Qin G, Zheng J, Chan P, et al. Inhibition of human natural killer cell activity by influenza virions and hemagglutinin. J Virol. 2010;84:4148-57 pubmed publisher
product information
Antigen :
CD247
Apps. Abbrev. :
WB, ICFC
Cat # :
644101
Clone :
6B10.2
Item :
Purified anti-CD247 (TCRζ, CD3ζ)
Isotype :
Mouse IgG1, κ
Other Names :
CD247, CD3zeta
Size :
25 μg
Price (USD) :
118 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Human TCR-zeta peptide
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA