product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-LAT
catalog :
641102
quantity :
100 μg
price :
229 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
11B.12
reactivity :
human, mouse
application :
western blot
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig s1
Muro R, Nitta T, Nakano K, Okamura T, Takayanagi H, Suzuki H. γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program. J Clin Invest. 2018;128:415-426 pubmed publisher
Shin J, Kwon M, Hwang J, Lee S, Lee J, Kim H, et al. Keratinocyte transglutaminase 2 promotes CCR6+ γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation. Cell Death Dis. 2020;11:301 pubmed publisher
Zhong C, Zheng M, Cui K, Martins A, Hu G, Li D, et al. Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells. Immunity. 2020;52:83-95.e4 pubmed publisher
Chen E, Tay N, Brzostek J, Gascoigne N, Rybakin V. A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation. Front Immunol. 2019;10:1718 pubmed publisher
Zhao X, Sankaran S, Yap J, Too C, Ho Z, Dolton G, et al. Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Nat Commun. 2018;9:2716 pubmed publisher
Deswal S, Schulze A, Hofer T, Schamel W. Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks. PLoS ONE. 2011;6:e22928 pubmed publisher
product information
Antigen :
LAT
Apps. Abbrev. :
WB
Cat # :
641102
Clone :
11B.12
Item :
Purified anti-LAT
Isotype :
Mouse IgG1, κ
Other Names :
Linker for activation of T-cells family member 1, pp36, p36-38
Size :
100 μg
Price (USD) :
229 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
GST fusion protein corresponding to residues 31-233 of human LAT, cytoplasmic domain.
Application Notes :
This clone may recognize a about 80 kD protein of unknown origin in some cell lines and tissue homogenates. It is also predicted to recognize rat LAT due to complete sequence homology between human, mouse, and rat LAT.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA