Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, et al. CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion. J Clin Invest. 2023;133: pubmed publisher

Jiang D, Huang H, Qin H, Tang K, Shi X, Zhu T, et al. Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma. Nat Commun. 2023;14:3642 pubmed publisher

Wyrobnik I, Steinberg M, Gelfand A, Rosenblum R, Eid Mutlak Y, Sulimani L, et al. Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progression. Oncoimmunology. 2023;12:2219164 pubmed publisher

Sun K, Jin L, Karolov xe1 J, Vorwerk J, Hailfinger S, Opalka B, et al. Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma. Cancers (Basel). 2023;15: pubmed publisher

Xiao C, Ren Z, Zhang B, Mao L, Zhu G, Gao L, et al. Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults. Nat Aging. 2023;3:418-435 pubmed publisher

Van Bael J, Vandenbulcke A, Ahmed Belkacem A, Guichou J, Pawlotsky J, Samyn J, et al. Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity. Int J Mol Sci. 2023;24: pubmed publisher

Pang J, Chien P, Kao M, Chiu P, Chen P, Hsu Y, et al. MicroRNA-708 emerges as a potential candidate to target undruggable NRAS. PLoS ONE. 2023;18:e0284744 pubmed publisher

Onyshchenko K, Luo R, Guffart E, Gaedicke S, Grosu A, Firat E, et al. Expansion of circulating stem-like CD8+ T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice. Nat Commun. 2023;14:2087 pubmed publisher

Chatterjee S, Naidu G, Hazan Halevy I, Grobe H, Ezra A, Sharma P, et al. Therapeutic gene silencing of CKAP5 leads to lethality in genetically unstable cancer cells. Sci Adv. 2023;9:eade4800 pubmed publisher

Perez G, Bernard M, Vocelle D, Zarea A, Saleh N, Gagea M, et al. Phosphatidylserine-Exposing Annexin A1-Positive Extracellular Vesicles: Potential Cancer Biomarkers. Vaccines (Basel). 2023;11: pubmed publisher

Riera Domingo C, Leite Gomes E, Charatsidou I, Zhao P, Carr xe1 G, Cappellesso F, et al. Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding. Sci Adv. 2023;9:eadd5028 pubmed publisher

Battistello E, Hixon K, Comstock D, Collings C, Chen X, Rodriguez Hernaez J, et al. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Mol Cell. 2023;83:1216-1236.e12 pubmed publisher

Giampaolo S, Chiarolla C, Kn xf6 pper K, Vaeth M, Klein M, Muhammad A, et al. NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation. iScience. 2023;26:106234 pubmed publisher

Daian L, Tanko G, Vacaru A, Ghila L, Chera S, Vacaru A. Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A. Int J Mol Sci. 2023;24: pubmed publisher

Di Benedetto C, Khan T, Serrano Saenz S, Rodriguez Lemus A, Klomsiri C, Beutel T, et al. Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis. Cancers (Basel). 2023;15: pubmed publisher

Liu X, Ye Y, Zhu L, Xiao X, Zhou B, Gu Y, et al. Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation. Nat Commun. 2023;14:238 pubmed publisher

Shiroshita K, Kobayashi H, Watanuki S, Karigane D, Sorimachi Y, Fujita S, et al. A culture platform to study quiescent hematopoietic stem cells following genome editing. Cell Rep Methods. 2022;2:100354 pubmed publisher

Cappellesso F, Orban M, Shirgaonkar N, Berardi E, Serneels J, Neveu M, et al. Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer. Nat Cancer. 2022;3:1464-1483 pubmed publisher

Hao J, Jin R, Zeng J, Hua Y, Yorek M, Liu L, et al. Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages. Cell Rep. 2022;41:111804 pubmed publisher

He C, Liu B, Wang H, Wu L, Zhao G, Huang C, et al. Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells. BMC Cancer. 2022;22:1100 pubmed publisher

McCartin C, Dussouillez C, Bernhard C, Mathieu E, Blumberger J, Dontenwill M, et al. Polyethylenimine, an Autophagy-Inducing Platinum-Carbene-Based Drug Carrier with Potent Toxicity towards Glioblastoma Cancer Stem Cells. Cancers (Basel). 2022;14: pubmed publisher

Li R, Ke M, Qi M, Han Z, Cao Y, Deng Z, et al. G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway. Exp Hematol Oncol. 2022;11:77 pubmed publisher

Christian D, Adams T, Shallberg L, Phan A, Smith T, Abraha M, et al. cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory. Sci Immunol. 2022;7:eabq7432 pubmed publisher

Chen Y, Qian J, Ding P, Wang W, Li X, Tang X, et al. Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation. Cell Death Dis. 2022;13:822 pubmed publisher

Ren Y, Kumar A, Das J, Peng H, Wang L, Balllard D, et al. Tumorous expression of NAC1 restrains antitumor immunity through the LDHA-mediated immune evasion. J Immunother Cancer. 2022;10: pubmed publisher

Hagege A, Saada Bouzid E, Ambrosetti D, Rastoin O, Boyer J, He X, et al. Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma. Cell Rep Med. 2022;3:100659 pubmed publisher

McCartin C, Mathieu E, Dontenwill M, Herold Mende C, Idbaih A, Bonfiglio A, et al. An N-heterocyclic carbene iridium(III) complex as a potent anti-cancer stem cell therapeutic. Chem Biol Interact. 2022;367:110167 pubmed publisher

Rodriguez Perdigon M, Jimaja S, Haeni L, Bruns N, Rothen Rutishauser B, R xfc egg C. Polymersomes-Mediated Delivery of CSF1R Inhibitor to Tumor Associated Macrophages Promotes M2 to M1-Like Macrophage Repolarization. Macromol Biosci. 2022;22:e2200168 pubmed publisher

Kalus P, De Munck J, Vanbellingen S, Carreer L, Laeremans T, Broos K, et al. Oncolytic Herpes Simplex Virus Type 1 Induces Immunogenic Cell Death Resulting in Maturation of BDCA-1+ Myeloid Dendritic Cells. Int J Mol Sci. 2022;23: pubmed publisher

Pedicona F, Casado P, Hijazi M, Gribben J, Rouault Pierre K, Cutillas P. Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment. Sci Signal. 2022;15:eabl7989 pubmed publisher

Roy S, Sinha N, Huang B, Cline Fedewa H, Gleicher N, Wang J, et al. Jumonji Domain-containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility. Endocrinology. 2022;163: pubmed publisher

Zhang H, Liu S, Li Y, Li J, Ni C, Yang M, et al. Dysfunction of S100A4+ effector memory CD8+ T cells aggravates asthma. Eur J Immunol. 2022;52:978-993 pubmed publisher

Walle T, Kraske J, Liao B, Lenoir B, Timke C, von Bohlen Und Halbach E, et al. Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8. Sci Adv. 2022;8:eabh4050 pubmed publisher

Hochrein S, Wu H, Eckstein M, Arrigoni L, Herman J, Schumacher F, et al. The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming. Cell Metab. 2022;34:516-532.e11 pubmed publisher

Lee Y, DiMaulo Milk E, Leslie J, Ding L. Hematopoietic stem cells temporally transition to thrombopoietin dependence in the fetal liver. Sci Adv. 2022;8:eabm7688 pubmed publisher

Lasrado N, Borcherding N, Arumugam R, Starr T, Reddy J. Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing. iScience. 2022;25:103865 pubmed publisher

Lee M, Hamilton J, Talekar G, Ross A, Michael L, Rupji M, et al. Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia. Nat Commun. 2022;13:1157 pubmed publisher

Cordo V, Meijer M, Hagelaar R, de Goeij de Haas R, Poort V, Henneman A, et al. Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies. Nat Commun. 2022;13:1048 pubmed publisher

Xiao C, Mao L, Wang Z, Gao L, Zhu G, Su J, et al. SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response. iScience. 2022;25:103934 pubmed publisher

Burclaff J, Bliton R, Breau K, Ok M, Gomez Martinez I, Ranek J, et al. A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics. Cell Mol Gastroenterol Hepatol. 2022;13:1554-1589 pubmed publisher

Schick M, Zhang L, Maurer S, Maurer H, Isaakaidis K, Schneider L, et al. Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma. Nat Commun. 2022;13:281 pubmed publisher

Celus W, Oliveira A, Rivis S, Van Acker H, Landeloos E, Serneels J, et al. Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer. Cancer Immunol Res. 2022;10:126-141 pubmed publisher

Sugiura A, Andrejeva G, Voss K, Heintzman D, Xu X, Madden M, et al. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022;55:65-81.e9 pubmed publisher

Warmuth S, Gunde T, Snell D, Brock M, Weinert C, Simonin A, et al. Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade. Oncoimmunology. 2021;10:2004661 pubmed publisher

Qiu C, Xiao C, Wang Z, Zhu G, Mao L, Chen X, et al. CD8+ T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2. Front Immunol. 2021;12:764949 pubmed publisher

Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Tsaktanis T, Naumann U, et al. Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation. Front Immunol. 2021;12:800128 pubmed publisher

Fleischmann M, Fischer M, Schnetzke U, Fortner C, Kirkpatrick J, Heidel F, et al. Modulation of FLT3-ITD Localization and Targeting of Distinct Downstream Signaling Pathways as Potential Strategies to Overcome FLT3-Inhibitor Resistance. Cells. 2021;10: pubmed publisher

McNeal A, Belote R, Zeng H, Urquijo M, Barker K, Torres R, et al. BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB. elife. 2021;10: pubmed publisher

Xu Y, Wang X, Yu M, Ruan Y, Zhang J, Tian Y, et al. Identification, subcellular localization, and functional comparison of novel Yap splicing isoforms in mouse embryonic stem cells. IUBMB Life. 2021;73:1432-1445 pubmed publisher

Deng J, Tian A, Pan H, Sauvat A, Leduc M, Liu P, et al. Everolimus and plicamycin specifically target chemoresistant colorectal cancer cells of the CMS4 subtype. Cell Death Dis. 2021;12:978 pubmed publisher

Dregalla R, Herrera J, Donner E. Red blood cells and their releasates compromise bone marrow-derived human mesenchymal stem/stromal cell survival in vitro. Stem Cell Res Ther. 2021;12:547 pubmed publisher

Cannons J, Villarino A, Kapnick S, Preite S, Shih H, Gomez Rodriguez J, et al. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory. Cell Rep. 2021;37:109804 pubmed publisher

Sahoo S, Pastor V, Goodings C, Voss R, Kozyra E, Szvetnik A, et al. Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. Nat Med. 2021;27:1806-1817 pubmed publisher

Patel R, Thomas J, Curt K, Fitzsimmons C, Batista P, Bates S, et al. Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma. Invest Ophthalmol Vis Sci. 2021;62:16 pubmed publisher

Millington Burgess S, Harper M. Epigallocatechin gallate inhibits release of extracellular vesicles from platelets without inhibiting phosphatidylserine exposure. Sci Rep. 2021;11:17678 pubmed publisher

Rausch M, Rutz A, Allard P, Delucinge Vivier C, Docquier M, Dormond O, et al. Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma. Cancers (Basel). 2021;13: pubmed publisher

Forsberg M, Kink J, Thickens A, Lewis B, Childs C, Hematti P, et al. Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome. Stem Cell Res Ther. 2021;12:459 pubmed publisher

Anderson C, Medina C, Barron B, Karvelyte L, Aaes T, Lambertz I, et al. Microbes exploit death-induced nutrient release by gut epithelial cells. Nature. 2021;596:262-267 pubmed publisher

Schäfer A, Eichhorst A, Hentze C, Kraemer A, Amend A, Sprenger D, et al. Low Dietary Fiber Intake Links Development of Obesity and Lupus Pathogenesis. Front Immunol. 2021;12:696810 pubmed publisher

Agarwal P, Li H, Choi K, Hueneman K, He J, Welner R, et al. TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling. Cell Rep. 2021;36:109386 pubmed publisher

Li C, Wang G, Sivasami P, Ramirez R, Zhang Y, Benoist C, et al. Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metab. 2021;33:1610-1623.e5 pubmed publisher

Chugh R, Park H, El Andaloussi A, Elsharoud A, Esfandyari S, Ulin M, et al. Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10. Stem Cell Res Ther. 2021;12:388 pubmed publisher

Li S, Jin H, Sun G, Zhang C, Wang J, Xu H, et al. Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress. Front Pharmacol. 2021;12:634115 pubmed publisher

Figueroa Vald xe9 s A, De la Fuente C, Hidalgo Y, Vega Letter A, Tapia Limonchi R, Khoury M, et al. A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells. Front Bioeng Biotechnol. 2021;9:619930 pubmed publisher

Preda M, Neculachi C, Fenyo I, Vacaru A, Publik M, Simionescu M, et al. Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice. Cell Death Dis. 2021;12:566 pubmed publisher

Song S, Kim S, El Sawy E, Cerella C, Orlikova Boyer B, Kirsch G, et al. Anti-Leukemic Properties of Aplysinopsin Derivative EE-84 Alone and Combined to BH3 Mimetic A-1210477. Mar Drugs. 2021;19: pubmed publisher

Ho J, Wang L, Liu Y, Ba M, Yang J, Zhang X, et al. Promoter usage regulating the surface density of CAR molecules may modulate the kinetics of CAR-T cells in vivo. Mol Ther Methods Clin Dev. 2021;21:237-246 pubmed publisher

Cai J, Gao H, Zhao J, Hu S, Liang X, Yang Y, et al. Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4+ T cells. elife. 2021;10: pubmed publisher

Pease N, Nguyen P, Woodworth M, Ng K, Irwin B, Vaughan J, et al. Tunable, division-independent control of gene activation timing by a polycomb switch. Cell Rep. 2021;34:108888 pubmed publisher

Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher

Dou R, Qian J, Wu W, Zhang Y, Yuan Y, Guo M, et al. Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. Cell Death Dis. 2021;12:206 pubmed publisher

Loo Yau H, Bell E, Ettayebi I, de Almeida F, Boukhaled G, Shen S, et al. DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells. Mol Cell. 2021;81:1469-1483.e8 pubmed publisher

Amend A, Wickli N, Schäfer A, Sprenger D, Manz R, Voll R, et al. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus. Int J Mol Sci. 2021;22: pubmed publisher

Parsa S, Ortega Molina A, Ying H, Jiang M, Teater M, Wang J, et al. The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. Nat Cancer. 2020;1:653-664 pubmed publisher

Tulasi D, Castaneda D, Wager K, Hogan C, Alcedo K, Raab J, et al. Sox9EGFP Defines Biliary Epithelial Heterogeneity Downstream of Yap Activity. Cell Mol Gastroenterol Hepatol. 2021;11:1437-1462 pubmed publisher

Okita R, Shimizu K, Nojima Y, Saisho S, Nakata M. Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad. Thorac Cancer. 2021;12:775-782 pubmed publisher

Mykhailova O, Turner T, Olafson C, Howell A, Nahirniak S, Wizniak J, et al. Hypothermic storage of leukoreduced red blood cells for greater than 21 days is a safe alternative to irradiation. Transfusion. 2021;61:1247-1257 pubmed publisher

Wei Z, Zhang X, Yong T, Bie N, Zhan G, Li X, et al. Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles. Nat Commun. 2021;12:440 pubmed publisher

Aslam M, Alemdehy M, Kwesi Maliepaard E, Muhaimin F, Caganova M, Pardieck I, et al. Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation. EMBO Rep. 2021;22:e51184 pubmed publisher

Wohlhieter C, Richards A, Uddin F, Hulton C, Quintanal Villalonga Á, Martin A, et al. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer. Cell Rep. 2020;33:108444 pubmed publisher

Hills L, Abdullah L, Lust H, Degefu H, Huang Y. Foxo1 Serine 209 Is a Critical Regulatory Site of CD8 T Cell Differentiation and Survival. J Immunol. 2021;206:89-100 pubmed publisher

Patel R, Kuhn S, Yin D, Hotz J, Maher F, Robey R, et al. Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms. Transl Oncol. 2021;14:100917 pubmed publisher

Cheng C, Wooten J, Gibbs Z, McGlynn K, Mishra P, Whitehurst A. Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma. elife. 2020;9: pubmed publisher

Zhang S, Shrestha C, Wisniewski B, Pham H, Hou X, Li W, et al. Consequences of CRISPR-Cas9-Mediated CFTR Knockout in Human Macrophages. Front Immunol. 2020;11:1871 pubmed publisher

Inclan Rico J, Ponessa J, Valero Pacheco N, Hernández C, Sy C, Lemenze A, et al. Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition. Nat Immunol. 2020;21:1181-1193 pubmed publisher

Festag J, Thelemann T, Schell M, Raith S, Michel S, Jaschinski F, et al. Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation. Mol Ther Nucleic Acids. 2020;21:656-669 pubmed publisher

Dong G, Li Y, Lee L, Liu X, Shi Y, Liu X, et al. Genetic manipulation of primary human natural killer cells to investigate the functional and oncogenic roles of PRDM1. Haematologica. 2020;: pubmed publisher

Chen Y, Li R, Zhu Y, Zhong S, Qian J, Yang D, et al. Dihydroartemisinin Induces Growth Arrest and Overcomes Dexamethasone Resistance in Multiple Myeloma. Front Oncol. 2020;10:767 pubmed publisher

Pothlichet J, Rose T, Bugault F, Jeammet L, Meola A, Haouz A, et al. PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients. J Clin Invest. 2020;130:2872-2887 pubmed publisher

Lei W, Duan R, Li J, Liu X, Huston A, Boyce B, et al. The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice. Sci Rep. 2020;10:7004 pubmed publisher

Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher

Liu L, Jin R, Hao J, Zeng J, Yin D, Yi Y, et al. Consumption of the Fish Oil High-Fat Diet Uncouples Obesity and Mammary Tumor Growth through Induction of Reactive Oxygen Species in Protumor Macrophages. Cancer Res. 2020;80:2564-2574 pubmed publisher

Muthalagu N, Monteverde T, Raffo Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, et al. Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2020;10:872-887 pubmed publisher

Moose D, Krog B, Kim T, Zhao L, Williams Perez S, Burke G, et al. Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation. Cell Rep. 2020;30:3864-3874.e6 pubmed publisher

Vongpipatana T, Nakahama T, Shibuya T, Kato Y, Kawahara Y. ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways. J Immunol. 2020;204:2156-2168 pubmed publisher

Høgh R, Droujinine A, Møller S, Jepsen S, Mellergaard M, Andresen L, et al. Fumarate Upregulates Surface Expression of ULBP2/ULBP5 by Scavenging Glutathione Antioxidant Capacity. J Immunol. 2020;204:1746-1759 pubmed publisher

Laughney A, Hu J, Campbell N, Bakhoum S, Setty M, Lavallée V, et al. Regenerative lineages and immune-mediated pruning in lung cancer metastasis. Nat Med. 2020;26:259-269 pubmed publisher

Hirata S, Nagatake T, Sawane K, Hosomi K, Honda T, Ono S, et al. Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice. Allergy. 2020;75:1939-1955 pubmed publisher

Wu N, Cernysiov V, Davidson D, Song H, Tang J, Luo S, et al. Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation. Cell Rep. 2020;30:1129-1140.e5 pubmed publisher

Hagan A, Zhang B, Ornitz D. Identification of a FGF18-expressing alveolar myofibroblast that is developmentally cleared during alveologenesis. Development. 2020;147: pubmed publisher

Yang X, Cheng X, Tang Y, Qiu X, Wang Y, Kang H, et al. Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure. Immunity. 2019;51:983-996.e6 pubmed publisher

Trigg R, Lee L, Prokoph N, Jahangiri L, Reynolds C, Amos Burke G, et al. The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status. Nat Commun. 2019;10:5428 pubmed publisher

Wallace J, Zambrano Rodas P, Córdova Calderón W, Estrada Turriate S, Mendoza Quispe D, Limache Ontiveros Y, et al. Dysregulated actin dynamics in activated PI3Kδ syndrome. Clin Immunol. 2020;210:108311 pubmed publisher

Liu L, Wang F, Tong Y, Li L, Liu Y, Gao W. Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction. Cell Prolif. 2019;:e12718 pubmed publisher

Barve A, Vega A, Shah P, Ghare S, Casson L, Wunderlich M, et al. Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia. Cells. 2019;8: pubmed publisher

Young M, Bui V, Chen C, Wang H. FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia. Cell Death Dis. 2019;10:847 pubmed publisher

Wiley C, Liu S, Limbad C, Zawadzka A, Beck J, Demaria M, et al. SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell Rep. 2019;28:3329-3337.e5 pubmed publisher

Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, et al. TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion. Cell Rep. 2019;28:1744-1757.e5 pubmed publisher

Qiu Z, Zhu W, Meng H, Tong L, Li X, Luo P, et al. CDYL promotes the chemoresistance of small cell lung cancer by regulating H3K27 trimethylation at the CDKN1C promoter. Theranostics. 2019;9:4717-4729 pubmed publisher

Zhang S, Goswami S, Ma J, Meng L, Wang Y, Zhu F, et al. CD4+T Cell Subset Profiling in Biliary Atresia Reveals ICOS- Regulatory T Cells as a Favorable Prognostic Factor. Front Pediatr. 2019;7:279 pubmed publisher

Burgener S, Leborgne N, Snipas S, Salvesen G, Bird P, Benarafa C. Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation. Cell Rep. 2019;27:3646-3656.e5 pubmed publisher

Hasselluhn M, Schmidt G, Ellenrieder V, Johnsen S, Hessmann E. Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression. Cell Death Dis. 2019;10:446 pubmed publisher

Sheng Y, Ji Z, Zhao H, Wang J, Cheng C, Xu W, et al. Downregulation of the histone methyltransferase SETD2 promotes imatinib resistance in chronic myeloid leukaemia cells. Cell Prolif. 2019;:e12611 pubmed publisher

Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, et al. YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis. Cell Rep. 2019;27:1176-1189.e5 pubmed publisher

Vig S, Buitinga M, Rondas D, Crèvecoeur I, van Zandvoort M, Waelkens E, et al. Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. Cell Death Dis. 2019;10:309 pubmed publisher

Ning X, Wang Y, Jing M, Sha M, Lv M, Gao P, et al. Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3. Mol Cell. 2019;74:19-31.e7 pubmed publisher

Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al. RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog. Theranostics. 2019;9:811-828 pubmed publisher

Kuljanin M, Elgamal R, Bell G, Xenocostas D, Xenocostas A, Hess D, et al. Quantitative Proteomics Evaluation of Human Multipotent Stromal Cell for β Cell Regeneration. Cell Rep. 2018;25:2524-2536.e4 pubmed publisher

Zhang S, Shrestha C, Kopp B. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function. Sci Rep. 2018;8:17066 pubmed publisher

Li B, Zhang S, Huang N, Chen H, Wang P, Yang J, et al. CCL9/CCR1 induces myeloid‑derived suppressor cell recruitment to the spleen in a murine H22 orthotopic hepatoma model. Oncol Rep. 2019;41:608-618 pubmed publisher

Sharma P, Puri N. Data confirming murine erythrocyte opsonization and oxidative damage and live microscopic analysis of oxidatively damaged erythrocyte uptake by mast cells. Data Brief. 2018;20:1645-1652 pubmed publisher

Saint Fleur Lominy S, Maus M, Vaeth M, Lange I, Zee I, Suh D, et al. STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep. 2018;24:3045-3060.e5 pubmed publisher

Dower C, Bhat N, Gebru M, Chen L, Wills C, Miller B, et al. Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma. Mol Cancer Ther. 2018;17:2365-2376 pubmed publisher

Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, et al. SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell. 2018;23:355-369.e9 pubmed publisher

Zeng H, Jorapur A, Shain A, Lang U, Torres R, Zhang Y, et al. Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation. Cancer Cell. 2018;34:56-68.e9 pubmed publisher

Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed publisher

Habtetsion T, Ding Z, Pi W, Li T, Lu C, Chen T, et al. Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death. Cell Metab. 2018;28:228-242.e6 pubmed publisher

Shinde R, Hezaveh K, Halaby M, Kloetgen A, Chakravarthy A, da Silva Medina T, et al. Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nat Immunol. 2018;19:571-582 pubmed publisher

Reyes Uribe P, Adrianzen Ruesta M, Deng Z, Echevarría Vargas I, Mender I, Saheb S, et al. Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma. Oncogene. 2018;37:4058-4072 pubmed publisher

Brasacchio D, Busuttil R, Noori T, Johnstone R, Boussioutas A, Trapani J. Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer. Cell Death Dis. 2018;9:442 pubmed publisher

Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, et al. Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation. JCI Insight. 2018;3: pubmed publisher

Voss O, Lee H, Tian L, Krzewski K, Coligan J. Liposome Preparation for the Analysis of Lipid-Receptor Interaction and Efferocytosis. Curr Protoc Immunol. 2018;120:14.44.1-14.44.21 pubmed publisher

Lima S, Takabe K, Newton J, Saurabh K, Young M, Leopoldino A, et al. TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition. Autophagy. 2018;14:942-957 pubmed publisher

Grossman L, Chang C, Dai J, Nikitin P, Jima D, Dave S, et al. Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines. mSphere. 2017;2: pubmed publisher

Oh J, Wang W, Thomas R, Su D. Capacity of tTreg generation is not impaired in the atrophied thymus. PLoS Biol. 2017;15:e2003352 pubmed publisher

Woolf N, Pearson B, Bondzie P, Meyer R, Lavaei M, Belkina A, et al. Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy. Oncogenesis. 2017;6:e378 pubmed publisher

Alamillo E, Reyes Becerril M, Cuesta A, Angulo C. Marine yeast Yarrowia lipolytica improves the immune responses in Pacific red snapper (Lutjanus peru) leukocytes. Fish Shellfish Immunol. 2017;70:48-56 pubmed publisher

Tang Z, Takahashi Y, Chen C, Liu Y, He H, Tsotakos N, et al. Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis. Cell Death Differ. 2017;24:2127-2138 pubmed publisher

Dai X, Zeng J, Yan X, Lin Q, Wang K, Chen J, et al. Sitagliptin-mediated preservation of endothelial progenitor cell function via augmenting autophagy enhances ischaemic angiogenesis in diabetes. J Cell Mol Med. 2018;22:89-100 pubmed publisher

Wu S, Niknafs Y, Kim S, Oravecz Wilson K, Zajac C, Toubai T, et al. A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation. Cell Rep. 2017;19:2645-2656 pubmed publisher

Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, et al. Tweety-Homolog 1 Drives Brain Colonization of Gliomas. J Neurosci. 2017;37:6837-6850 pubmed publisher

Zeriouh W, Nani A, Belarbi M, Dumont A, de Rosny C, Aboura I, et al. Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway. PLoS ONE. 2017;12:e0170823 pubmed publisher

Xu B, Lefringhouse J, Liu Z, West D, Baldwin L, Ou C, et al. Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy. Oncogenesis. 2017;6:e295 pubmed publisher

Ponath V, Kaina B. Death of Monocytes through Oxidative Burst of Macrophages and Neutrophils: Killing in Trans. PLoS ONE. 2017;12:e0170347 pubmed publisher

Perny M, Muri L, Dawson H, Kleinlogel S. Chronic activation of the D156A point mutant of Channelrhodopsin-2 signals apoptotic cell death: the good and the bad. Cell Death Dis. 2016;7:e2447 pubmed publisher

Li L, Yang S, Yao Y, Xie Y, Yang Y, Wang Y, et al. Block of both TGF-β and IL-2 signaling impedes Neurophilin-1+ regulatory T cell and follicular regulatory T cell development. Cell Death Dis. 2016;7:e2439 pubmed publisher

Sumitomo Y, Koya J, Nakazaki K, Kataoka K, Tsuruta Kishino T, Morita K, et al. Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia. Blood. 2016;128:1614-24 pubmed publisher

Kostadinova E, Chaput C, Gutbier B, Lippmann J, Sander L, Mitchell T, et al. NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence. Sci Rep. 2016;6:30943 pubmed publisher

Höhne K, Businger R, Van Nuffel A, Bolduan S, Koppensteiner H, Baeyens A, et al. Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection. Open Biol. 2016;6: pubmed publisher

Vickman R, Crist S, Kerian K, Eberlin L, Cooks R, Burcham G, et al. Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer. Mol Cancer Res. 2016;14:776-86 pubmed publisher

Fernandez D, Flores Santibáñez F, Neira J, Osorio Barrios F, Tejon G, Nuñez S, et al. Purinergic Signaling as a Regulator of Th17 Cell Plasticity. PLoS ONE. 2016;11:e0157889 pubmed publisher

Cao W, Guo J, Wen X, Miao L, Lin F, Xu G, et al. CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation. Nat Commun. 2016;7:11687 pubmed publisher

Hickman O, Smith R, Dasgupta P, Rao S, Nayak S, Sreenivasan S, et al. Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2. Br J Cancer. 2016;114:1235-42 pubmed publisher

Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph K. Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat Cell Biol. 2016;18:480-90 pubmed publisher

O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed publisher

Yamamoto H, Lu J, Oba S, Kawamata T, Yoshimi A, Kurosaki N, et al. miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target. Sci Rep. 2016;6:19204 pubmed publisher

Satcher R, Pan T, Bilen M, Li X, Lee Y, Ortiz A, et al. Cadherin-11 endocytosis through binding to clathrin promotes cadherin-11-mediated migration in prostate cancer cells. J Cell Sci. 2015;128:4629-41 pubmed publisher

Cabet E, Batonnet Pichon S, Delort F, Gausserès B, Vicart P, Lilienbaum A. Antioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of Desminopathy. PLoS ONE. 2015;10:e0137009 pubmed publisher

Weiser J, Roche A, Hergott C, LaRose M, Connolly T, Jorgensen W, et al. Macrophage Migration Inhibitory Factor Is Detrimental in Pneumococcal Pneumonia and a Target for Therapeutic Immunomodulation. J Infect Dis. 2015;212:1677-82 pubmed publisher

Isobe T, Hisamori S, Hogan D, Zabala M, Hendrickson D, Dalerba P, et al. miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway. elife. 2014;3: pubmed publisher

Feng Q, Langereis M, Olagnier D, Chiang C, van de Winkel R, van Essen P, et al. Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation. PLoS ONE. 2014;9:e95927 pubmed publisher

Hussain M, Baig S, Neumann S, Peche V, Szczepanski S, Nurnberg G, et al. CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013;22:5199-214 pubmed publisher