Reference |
---|
Kugler E, Madiwale S, Yong D, Thoms J, Birger Y, Sykes D, et al. The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG. Nat Commun. 2023;14:5871 pubmed publisher
|
Jiang D, Huang H, Qin H, Tang K, Shi X, Zhu T, et al. Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma. Nat Commun. 2023;14:3642 pubmed publisher
|
Wyrobnik I, Steinberg M, Gelfand A, Rosenblum R, Eid Mutlak Y, Sulimani L, et al. Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progression. Oncoimmunology. 2023;12:2219164 pubmed publisher
|
Sun K, Jin L, Karolov xe1 J, Vorwerk J, Hailfinger S, Opalka B, et al. Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma. Cancers (Basel). 2023;15: pubmed publisher
|
Xiao C, Ren Z, Zhang B, Mao L, Zhu G, Gao L, et al. Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults. Nat Aging. 2023;3:418-435 pubmed publisher
|
Van Bael J, Vandenbulcke A, Ahmed Belkacem A, Guichou J, Pawlotsky J, Samyn J, et al. Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity. Int J Mol Sci. 2023;24: pubmed publisher
|
Pang J, Chien P, Kao M, Chiu P, Chen P, Hsu Y, et al. MicroRNA-708 emerges as a potential candidate to target undruggable NRAS. PLoS ONE. 2023;18:e0284744 pubmed publisher
|
Onyshchenko K, Luo R, Guffart E, Gaedicke S, Grosu A, Firat E, et al. Expansion of circulating stem-like CD8+ T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice. Nat Commun. 2023;14:2087 pubmed publisher
|
Chatterjee S, Naidu G, Hazan Halevy I, Grobe H, Ezra A, Sharma P, et al. Therapeutic gene silencing of CKAP5 leads to lethality in genetically unstable cancer cells. Sci Adv. 2023;9:eade4800 pubmed publisher
|
Perez G, Bernard M, Vocelle D, Zarea A, Saleh N, Gagea M, et al. Phosphatidylserine-Exposing Annexin A1-Positive Extracellular Vesicles: Potential Cancer Biomarkers. Vaccines (Basel). 2023;11: pubmed publisher
|
Riera Domingo C, Leite Gomes E, Charatsidou I, Zhao P, Carr xe1 G, Cappellesso F, et al. Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding. Sci Adv. 2023;9:eadd5028 pubmed publisher
|
Battistello E, Hixon K, Comstock D, Collings C, Chen X, Rodriguez Hernaez J, et al. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Mol Cell. 2023;83:1216-1236.e12 pubmed publisher
|
Giampaolo S, Chiarolla C, Kn xf6 pper K, Vaeth M, Klein M, Muhammad A, et al. NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation. iScience. 2023;26:106234 pubmed publisher
|
Daian L, Tanko G, Vacaru A, Ghila L, Chera S, Vacaru A. Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A. Int J Mol Sci. 2023;24: pubmed publisher
|
Di Benedetto C, Khan T, Serrano Saenz S, Rodriguez Lemus A, Klomsiri C, Beutel T, et al. Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis. Cancers (Basel). 2023;15: pubmed publisher
|
Liu X, Ye Y, Zhu L, Xiao X, Zhou B, Gu Y, et al. Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation. Nat Commun. 2023;14:238 pubmed publisher
|
Shiroshita K, Kobayashi H, Watanuki S, Karigane D, Sorimachi Y, Fujita S, et al. A culture platform to study quiescent hematopoietic stem cells following genome editing. Cell Rep Methods. 2022;2:100354 pubmed publisher
|
Cappellesso F, Orban M, Shirgaonkar N, Berardi E, Serneels J, Neveu M, et al. Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer. Nat Cancer. 2022;3:1464-1483 pubmed publisher
|
Hao J, Jin R, Zeng J, Hua Y, Yorek M, Liu L, et al. Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages. Cell Rep. 2022;41:111804 pubmed publisher
|
He C, Liu B, Wang H, Wu L, Zhao G, Huang C, et al. Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells. BMC Cancer. 2022;22:1100 pubmed publisher
|
McCartin C, Dussouillez C, Bernhard C, Mathieu E, Blumberger J, Dontenwill M, et al. Polyethylenimine, an Autophagy-Inducing Platinum-Carbene-Based Drug Carrier with Potent Toxicity towards Glioblastoma Cancer Stem Cells. Cancers (Basel). 2022;14: pubmed publisher
|
Li R, Ke M, Qi M, Han Z, Cao Y, Deng Z, et al. G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway. Exp Hematol Oncol. 2022;11:77 pubmed publisher
|
Christian D, Adams T, Shallberg L, Phan A, Smith T, Abraha M, et al. cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory. Sci Immunol. 2022;7:eabq7432 pubmed publisher
|
Chen Y, Qian J, Ding P, Wang W, Li X, Tang X, et al. Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation. Cell Death Dis. 2022;13:822 pubmed publisher
|
Ren Y, Kumar A, Das J, Peng H, Wang L, Balllard D, et al. Tumorous expression of NAC1 restrains antitumor immunity through the LDHA-mediated immune evasion. J Immunother Cancer. 2022;10: pubmed publisher
|
Hagege A, Saada Bouzid E, Ambrosetti D, Rastoin O, Boyer J, He X, et al. Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma. Cell Rep Med. 2022;3:100659 pubmed publisher
|
McCartin C, Mathieu E, Dontenwill M, Herold Mende C, Idbaih A, Bonfiglio A, et al. An N-heterocyclic carbene iridium(III) complex as a potent anti-cancer stem cell therapeutic. Chem Biol Interact. 2022;367:110167 pubmed publisher
|
Rodriguez Perdigon M, Jimaja S, Haeni L, Bruns N, Rothen Rutishauser B, R xfc egg C. Polymersomes-Mediated Delivery of CSF1R Inhibitor to Tumor Associated Macrophages Promotes M2 to M1-Like Macrophage Repolarization. Macromol Biosci. 2022;22:e2200168 pubmed publisher
|
Kalus P, De Munck J, Vanbellingen S, Carreer L, Laeremans T, Broos K, et al. Oncolytic Herpes Simplex Virus Type 1 Induces Immunogenic Cell Death Resulting in Maturation of BDCA-1+ Myeloid Dendritic Cells. Int J Mol Sci. 2022;23: pubmed publisher
|
Pedicona F, Casado P, Hijazi M, Gribben J, Rouault Pierre K, Cutillas P. Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment. Sci Signal. 2022;15:eabl7989 pubmed publisher
|
Roy S, Sinha N, Huang B, Cline Fedewa H, Gleicher N, Wang J, et al. Jumonji Domain-containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility. Endocrinology. 2022;163: pubmed publisher
|
Zhang H, Liu S, Li Y, Li J, Ni C, Yang M, et al. Dysfunction of S100A4+ effector memory CD8+ T cells aggravates asthma. Eur J Immunol. 2022;52:978-993 pubmed publisher
|
Walle T, Kraske J, Liao B, Lenoir B, Timke C, von Bohlen Und Halbach E, et al. Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8. Sci Adv. 2022;8:eabh4050 pubmed publisher
|
Hochrein S, Wu H, Eckstein M, Arrigoni L, Herman J, Schumacher F, et al. The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming. Cell Metab. 2022;34:516-532.e11 pubmed publisher
|
Lee Y, DiMaulo Milk E, Leslie J, Ding L. Hematopoietic stem cells temporally transition to thrombopoietin dependence in the fetal liver. Sci Adv. 2022;8:eabm7688 pubmed publisher
|
Lasrado N, Borcherding N, Arumugam R, Starr T, Reddy J. Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing. iScience. 2022;25:103865 pubmed publisher
|
Lee M, Hamilton J, Talekar G, Ross A, Michael L, Rupji M, et al. Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia. Nat Commun. 2022;13:1157 pubmed publisher
|
Cordo V, Meijer M, Hagelaar R, de Goeij de Haas R, Poort V, Henneman A, et al. Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies. Nat Commun. 2022;13:1048 pubmed publisher
|
Xiao C, Mao L, Wang Z, Gao L, Zhu G, Su J, et al. SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response. iScience. 2022;25:103934 pubmed publisher
|
Burclaff J, Bliton R, Breau K, Ok M, Gomez Martinez I, Ranek J, et al. A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics. Cell Mol Gastroenterol Hepatol. 2022;13:1554-1589 pubmed publisher
|
Schick M, Zhang L, Maurer S, Maurer H, Isaakaidis K, Schneider L, et al. Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma. Nat Commun. 2022;13:281 pubmed publisher
|
Celus W, Oliveira A, Rivis S, Van Acker H, Landeloos E, Serneels J, et al. Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer. Cancer Immunol Res. 2022;10:126-141 pubmed publisher
|
Sugiura A, Andrejeva G, Voss K, Heintzman D, Xu X, Madden M, et al. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022;55:65-81.e9 pubmed publisher
|
Warmuth S, Gunde T, Snell D, Brock M, Weinert C, Simonin A, et al. Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade. Oncoimmunology. 2021;10:2004661 pubmed publisher
|
Qiu C, Xiao C, Wang Z, Zhu G, Mao L, Chen X, et al. CD8+ T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2. Front Immunol. 2021;12:764949 pubmed publisher
|
Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Tsaktanis T, Naumann U, et al. Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation. Front Immunol. 2021;12:800128 pubmed publisher
|
Fleischmann M, Fischer M, Schnetzke U, Fortner C, Kirkpatrick J, Heidel F, et al. Modulation of FLT3-ITD Localization and Targeting of Distinct Downstream Signaling Pathways as Potential Strategies to Overcome FLT3-Inhibitor Resistance. Cells. 2021;10: pubmed publisher
|
McNeal A, Belote R, Zeng H, Urquijo M, Barker K, Torres R, et al. BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB. elife. 2021;10: pubmed publisher
|
Xu Y, Wang X, Yu M, Ruan Y, Zhang J, Tian Y, et al. Identification, subcellular localization, and functional comparison of novel Yap splicing isoforms in mouse embryonic stem cells. IUBMB Life. 2021;73:1432-1445 pubmed publisher
|
Deng J, Tian A, Pan H, Sauvat A, Leduc M, Liu P, et al. Everolimus and plicamycin specifically target chemoresistant colorectal cancer cells of the CMS4 subtype. Cell Death Dis. 2021;12:978 pubmed publisher
|
Dregalla R, Herrera J, Donner E. Red blood cells and their releasates compromise bone marrow-derived human mesenchymal stem/stromal cell survival in vitro. Stem Cell Res Ther. 2021;12:547 pubmed publisher
|
Cannons J, Villarino A, Kapnick S, Preite S, Shih H, Gomez Rodriguez J, et al. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory. Cell Rep. 2021;37:109804 pubmed publisher
|
Sahoo S, Pastor V, Goodings C, Voss R, Kozyra E, Szvetnik A, et al. Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. Nat Med. 2021;27:1806-1817 pubmed publisher
|
Patel R, Thomas J, Curt K, Fitzsimmons C, Batista P, Bates S, et al. Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma. Invest Ophthalmol Vis Sci. 2021;62:16 pubmed publisher
|
Millington Burgess S, Harper M. Epigallocatechin gallate inhibits release of extracellular vesicles from platelets without inhibiting phosphatidylserine exposure. Sci Rep. 2021;11:17678 pubmed publisher
|
Rausch M, Rutz A, Allard P, Delucinge Vivier C, Docquier M, Dormond O, et al. Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma. Cancers (Basel). 2021;13: pubmed publisher
|
Forsberg M, Kink J, Thickens A, Lewis B, Childs C, Hematti P, et al. Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome. Stem Cell Res Ther. 2021;12:459 pubmed publisher
|
Anderson C, Medina C, Barron B, Karvelyte L, Aaes T, Lambertz I, et al. Microbes exploit death-induced nutrient release by gut epithelial cells. Nature. 2021;596:262-267 pubmed publisher
|
Schäfer A, Eichhorst A, Hentze C, Kraemer A, Amend A, Sprenger D, et al. Low Dietary Fiber Intake Links Development of Obesity and Lupus Pathogenesis. Front Immunol. 2021;12:696810 pubmed publisher
|
Agarwal P, Li H, Choi K, Hueneman K, He J, Welner R, et al. TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling. Cell Rep. 2021;36:109386 pubmed publisher
|
Li C, Wang G, Sivasami P, Ramirez R, Zhang Y, Benoist C, et al. Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metab. 2021;33:1610-1623.e5 pubmed publisher
|
Chugh R, Park H, El Andaloussi A, Elsharoud A, Esfandyari S, Ulin M, et al. Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10. Stem Cell Res Ther. 2021;12:388 pubmed publisher
|
Li S, Jin H, Sun G, Zhang C, Wang J, Xu H, et al. Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress. Front Pharmacol. 2021;12:634115 pubmed publisher
|
Figueroa Vald xe9 s A, De la Fuente C, Hidalgo Y, Vega Letter A, Tapia Limonchi R, Khoury M, et al. A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells. Front Bioeng Biotechnol. 2021;9:619930 pubmed publisher
|
Preda M, Neculachi C, Fenyo I, Vacaru A, Publik M, Simionescu M, et al. Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice. Cell Death Dis. 2021;12:566 pubmed publisher
|
Song S, Kim S, El Sawy E, Cerella C, Orlikova Boyer B, Kirsch G, et al. Anti-Leukemic Properties of Aplysinopsin Derivative EE-84 Alone and Combined to BH3 Mimetic A-1210477. Mar Drugs. 2021;19: pubmed publisher
|
Ho J, Wang L, Liu Y, Ba M, Yang J, Zhang X, et al. Promoter usage regulating the surface density of CAR molecules may modulate the kinetics of CAR-T cells in vivo. Mol Ther Methods Clin Dev. 2021;21:237-246 pubmed publisher
|
Cai J, Gao H, Zhao J, Hu S, Liang X, Yang Y, et al. Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4+ T cells. elife. 2021;10: pubmed publisher
|
Pease N, Nguyen P, Woodworth M, Ng K, Irwin B, Vaughan J, et al. Tunable, division-independent control of gene activation timing by a polycomb switch. Cell Rep. 2021;34:108888 pubmed publisher
|
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher
|
Dou R, Qian J, Wu W, Zhang Y, Yuan Y, Guo M, et al. Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. Cell Death Dis. 2021;12:206 pubmed publisher
|
Loo Yau H, Bell E, Ettayebi I, de Almeida F, Boukhaled G, Shen S, et al. DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells. Mol Cell. 2021;81:1469-1483.e8 pubmed publisher
|
Amend A, Wickli N, Schäfer A, Sprenger D, Manz R, Voll R, et al. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus. Int J Mol Sci. 2021;22: pubmed publisher
|
Parsa S, Ortega Molina A, Ying H, Jiang M, Teater M, Wang J, et al. The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. Nat Cancer. 2020;1:653-664 pubmed publisher
|
Tulasi D, Castaneda D, Wager K, Hogan C, Alcedo K, Raab J, et al. Sox9EGFP Defines Biliary Epithelial Heterogeneity Downstream of Yap Activity. Cell Mol Gastroenterol Hepatol. 2021;11:1437-1462 pubmed publisher
|
Okita R, Shimizu K, Nojima Y, Saisho S, Nakata M. Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad. Thorac Cancer. 2021;12:775-782 pubmed publisher
|
Mykhailova O, Turner T, Olafson C, Howell A, Nahirniak S, Wizniak J, et al. Hypothermic storage of leukoreduced red blood cells for greater than 21 days is a safe alternative to irradiation. Transfusion. 2021;61:1247-1257 pubmed publisher
|
Wei Z, Zhang X, Yong T, Bie N, Zhan G, Li X, et al. Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles. Nat Commun. 2021;12:440 pubmed publisher
|
Aslam M, Alemdehy M, Kwesi Maliepaard E, Muhaimin F, Caganova M, Pardieck I, et al. Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation. EMBO Rep. 2021;22:e51184 pubmed publisher
|
Wohlhieter C, Richards A, Uddin F, Hulton C, Quintanal Villalonga Á, Martin A, et al. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer. Cell Rep. 2020;33:108444 pubmed publisher
|
Hills L, Abdullah L, Lust H, Degefu H, Huang Y. Foxo1 Serine 209 Is a Critical Regulatory Site of CD8 T Cell Differentiation and Survival. J Immunol. 2021;206:89-100 pubmed publisher
|
Patel R, Kuhn S, Yin D, Hotz J, Maher F, Robey R, et al. Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms. Transl Oncol. 2021;14:100917 pubmed publisher
|
Cheng C, Wooten J, Gibbs Z, McGlynn K, Mishra P, Whitehurst A. Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma. elife. 2020;9: pubmed publisher
|
Zhang S, Shrestha C, Wisniewski B, Pham H, Hou X, Li W, et al. Consequences of CRISPR-Cas9-Mediated CFTR Knockout in Human Macrophages. Front Immunol. 2020;11:1871 pubmed publisher
|
Inclan Rico J, Ponessa J, Valero Pacheco N, Hernández C, Sy C, Lemenze A, et al. Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition. Nat Immunol. 2020;21:1181-1193 pubmed publisher
|
Festag J, Thelemann T, Schell M, Raith S, Michel S, Jaschinski F, et al. Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation. Mol Ther Nucleic Acids. 2020;21:656-669 pubmed publisher
|
Dong G, Li Y, Lee L, Liu X, Shi Y, Liu X, et al. Genetic manipulation of primary human natural killer cells to investigate the functional and oncogenic roles of PRDM1. Haematologica. 2020;: pubmed publisher
|
Chen Y, Li R, Zhu Y, Zhong S, Qian J, Yang D, et al. Dihydroartemisinin Induces Growth Arrest and Overcomes Dexamethasone Resistance in Multiple Myeloma. Front Oncol. 2020;10:767 pubmed publisher
|
Pothlichet J, Rose T, Bugault F, Jeammet L, Meola A, Haouz A, et al. PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients. J Clin Invest. 2020;130:2872-2887 pubmed publisher
|
Lei W, Duan R, Li J, Liu X, Huston A, Boyce B, et al. The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice. Sci Rep. 2020;10:7004 pubmed publisher
|
Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher
|
Liu L, Jin R, Hao J, Zeng J, Yin D, Yi Y, et al. Consumption of the Fish Oil High-Fat Diet Uncouples Obesity and Mammary Tumor Growth through Induction of Reactive Oxygen Species in Protumor Macrophages. Cancer Res. 2020;80:2564-2574 pubmed publisher
|
Muthalagu N, Monteverde T, Raffo Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, et al. Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2020;10:872-887 pubmed publisher
|
Moose D, Krog B, Kim T, Zhao L, Williams Perez S, Burke G, et al. Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation. Cell Rep. 2020;30:3864-3874.e6 pubmed publisher
|
Vongpipatana T, Nakahama T, Shibuya T, Kato Y, Kawahara Y. ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways. J Immunol. 2020;204:2156-2168 pubmed publisher
|
Høgh R, Droujinine A, Møller S, Jepsen S, Mellergaard M, Andresen L, et al. Fumarate Upregulates Surface Expression of ULBP2/ULBP5 by Scavenging Glutathione Antioxidant Capacity. J Immunol. 2020;204:1746-1759 pubmed publisher
|
Laughney A, Hu J, Campbell N, Bakhoum S, Setty M, Lavallée V, et al. Regenerative lineages and immune-mediated pruning in lung cancer metastasis. Nat Med. 2020;26:259-269 pubmed publisher
|
Hirata S, Nagatake T, Sawane K, Hosomi K, Honda T, Ono S, et al. Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice. Allergy. 2020;75:1939-1955 pubmed publisher
|
Wu N, Cernysiov V, Davidson D, Song H, Tang J, Luo S, et al. Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation. Cell Rep. 2020;30:1129-1140.e5 pubmed publisher
|
Hagan A, Zhang B, Ornitz D. Identification of a FGF18-expressing alveolar myofibroblast that is developmentally cleared during alveologenesis. Development. 2020;147: pubmed publisher
|
Yang X, Cheng X, Tang Y, Qiu X, Wang Y, Kang H, et al. Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure. Immunity. 2019;51:983-996.e6 pubmed publisher
|
Trigg R, Lee L, Prokoph N, Jahangiri L, Reynolds C, Amos Burke G, et al. The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status. Nat Commun. 2019;10:5428 pubmed publisher
|
Wallace J, Zambrano Rodas P, Córdova Calderón W, Estrada Turriate S, Mendoza Quispe D, Limache Ontiveros Y, et al. Dysregulated actin dynamics in activated PI3Kδ syndrome. Clin Immunol. 2020;210:108311 pubmed publisher
|
Liu L, Wang F, Tong Y, Li L, Liu Y, Gao W. Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction. Cell Prolif. 2019;:e12718 pubmed publisher
|
Barve A, Vega A, Shah P, Ghare S, Casson L, Wunderlich M, et al. Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia. Cells. 2019;8: pubmed publisher
|
Young M, Bui V, Chen C, Wang H. FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia. Cell Death Dis. 2019;10:847 pubmed publisher
|
Wiley C, Liu S, Limbad C, Zawadzka A, Beck J, Demaria M, et al. SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell Rep. 2019;28:3329-3337.e5 pubmed publisher
|
Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, et al. TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion. Cell Rep. 2019;28:1744-1757.e5 pubmed publisher
|
Qiu Z, Zhu W, Meng H, Tong L, Li X, Luo P, et al. CDYL promotes the chemoresistance of small cell lung cancer by regulating H3K27 trimethylation at the CDKN1C promoter. Theranostics. 2019;9:4717-4729 pubmed publisher
|
Zhang S, Goswami S, Ma J, Meng L, Wang Y, Zhu F, et al. CD4+T Cell Subset Profiling in Biliary Atresia Reveals ICOS- Regulatory T Cells as a Favorable Prognostic Factor. Front Pediatr. 2019;7:279 pubmed publisher
|
Burgener S, Leborgne N, Snipas S, Salvesen G, Bird P, Benarafa C. Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation. Cell Rep. 2019;27:3646-3656.e5 pubmed publisher
|
Hasselluhn M, Schmidt G, Ellenrieder V, Johnsen S, Hessmann E. Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression. Cell Death Dis. 2019;10:446 pubmed publisher
|
Sheng Y, Ji Z, Zhao H, Wang J, Cheng C, Xu W, et al. Downregulation of the histone methyltransferase SETD2 promotes imatinib resistance in chronic myeloid leukaemia cells. Cell Prolif. 2019;:e12611 pubmed publisher
|
Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, et al. YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis. Cell Rep. 2019;27:1176-1189.e5 pubmed publisher
|
Vig S, Buitinga M, Rondas D, Crèvecoeur I, van Zandvoort M, Waelkens E, et al. Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. Cell Death Dis. 2019;10:309 pubmed publisher
|
Ning X, Wang Y, Jing M, Sha M, Lv M, Gao P, et al. Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3. Mol Cell. 2019;74:19-31.e7 pubmed publisher
|
Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al. RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog. Theranostics. 2019;9:811-828 pubmed publisher
|
Kuljanin M, Elgamal R, Bell G, Xenocostas D, Xenocostas A, Hess D, et al. Quantitative Proteomics Evaluation of Human Multipotent Stromal Cell for β Cell Regeneration. Cell Rep. 2018;25:2524-2536.e4 pubmed publisher
|
Zhang S, Shrestha C, Kopp B. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function. Sci Rep. 2018;8:17066 pubmed publisher
|
Li B, Zhang S, Huang N, Chen H, Wang P, Yang J, et al. CCL9/CCR1 induces myeloid‑derived suppressor cell recruitment to the spleen in a murine H22 orthotopic hepatoma model. Oncol Rep. 2019;41:608-618 pubmed publisher
|
Sharma P, Puri N. Data confirming murine erythrocyte opsonization and oxidative damage and live microscopic analysis of oxidatively damaged erythrocyte uptake by mast cells. Data Brief. 2018;20:1645-1652 pubmed publisher
|
Saint Fleur Lominy S, Maus M, Vaeth M, Lange I, Zee I, Suh D, et al. STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep. 2018;24:3045-3060.e5 pubmed publisher
|
Dower C, Bhat N, Gebru M, Chen L, Wills C, Miller B, et al. Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma. Mol Cancer Ther. 2018;17:2365-2376 pubmed publisher
|
Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, et al. SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell. 2018;23:355-369.e9 pubmed publisher
|
Zeng H, Jorapur A, Shain A, Lang U, Torres R, Zhang Y, et al. Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation. Cancer Cell. 2018;34:56-68.e9 pubmed publisher
|
Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed publisher
|
Habtetsion T, Ding Z, Pi W, Li T, Lu C, Chen T, et al. Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death. Cell Metab. 2018;28:228-242.e6 pubmed publisher
|
Shinde R, Hezaveh K, Halaby M, Kloetgen A, Chakravarthy A, da Silva Medina T, et al. Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nat Immunol. 2018;19:571-582 pubmed publisher
|
Reyes Uribe P, Adrianzen Ruesta M, Deng Z, Echevarría Vargas I, Mender I, Saheb S, et al. Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma. Oncogene. 2018;37:4058-4072 pubmed publisher
|
Brasacchio D, Busuttil R, Noori T, Johnstone R, Boussioutas A, Trapani J. Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer. Cell Death Dis. 2018;9:442 pubmed publisher
|
Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, et al. Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation. JCI Insight. 2018;3: pubmed publisher
|
Voss O, Lee H, Tian L, Krzewski K, Coligan J. Liposome Preparation for the Analysis of Lipid-Receptor Interaction and Efferocytosis. Curr Protoc Immunol. 2018;120:14.44.1-14.44.21 pubmed publisher
|
Lima S, Takabe K, Newton J, Saurabh K, Young M, Leopoldino A, et al. TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition. Autophagy. 2018;14:942-957 pubmed publisher
|
Grossman L, Chang C, Dai J, Nikitin P, Jima D, Dave S, et al. Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines. mSphere. 2017;2: pubmed publisher
|
Oh J, Wang W, Thomas R, Su D. Capacity of tTreg generation is not impaired in the atrophied thymus. PLoS Biol. 2017;15:e2003352 pubmed publisher
|
Woolf N, Pearson B, Bondzie P, Meyer R, Lavaei M, Belkina A, et al. Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy. Oncogenesis. 2017;6:e378 pubmed publisher
|
Alamillo E, Reyes Becerril M, Cuesta A, Angulo C. Marine yeast Yarrowia lipolytica improves the immune responses in Pacific red snapper (Lutjanus peru) leukocytes. Fish Shellfish Immunol. 2017;70:48-56 pubmed publisher
|
Tang Z, Takahashi Y, Chen C, Liu Y, He H, Tsotakos N, et al. Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis. Cell Death Differ. 2017;24:2127-2138 pubmed publisher
|
Dai X, Zeng J, Yan X, Lin Q, Wang K, Chen J, et al. Sitagliptin-mediated preservation of endothelial progenitor cell function via augmenting autophagy enhances ischaemic angiogenesis in diabetes. J Cell Mol Med. 2018;22:89-100 pubmed publisher
|
Wu S, Niknafs Y, Kim S, Oravecz Wilson K, Zajac C, Toubai T, et al. A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation. Cell Rep. 2017;19:2645-2656 pubmed publisher
|
Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, et al. Tweety-Homolog 1 Drives Brain Colonization of Gliomas. J Neurosci. 2017;37:6837-6850 pubmed publisher
|
Zeriouh W, Nani A, Belarbi M, Dumont A, de Rosny C, Aboura I, et al. Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway. PLoS ONE. 2017;12:e0170823 pubmed publisher
|
Xu B, Lefringhouse J, Liu Z, West D, Baldwin L, Ou C, et al. Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy. Oncogenesis. 2017;6:e295 pubmed publisher
|
Ponath V, Kaina B. Death of Monocytes through Oxidative Burst of Macrophages and Neutrophils: Killing in Trans. PLoS ONE. 2017;12:e0170347 pubmed publisher
|
Perny M, Muri L, Dawson H, Kleinlogel S. Chronic activation of the D156A point mutant of Channelrhodopsin-2 signals apoptotic cell death: the good and the bad. Cell Death Dis. 2016;7:e2447 pubmed publisher
|
Li L, Yang S, Yao Y, Xie Y, Yang Y, Wang Y, et al. Block of both TGF-β and IL-2 signaling impedes Neurophilin-1+ regulatory T cell and follicular regulatory T cell development. Cell Death Dis. 2016;7:e2439 pubmed publisher
|
Sumitomo Y, Koya J, Nakazaki K, Kataoka K, Tsuruta Kishino T, Morita K, et al. Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia. Blood. 2016;128:1614-24 pubmed publisher
|
Kostadinova E, Chaput C, Gutbier B, Lippmann J, Sander L, Mitchell T, et al. NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence. Sci Rep. 2016;6:30943 pubmed publisher
|
Höhne K, Businger R, Van Nuffel A, Bolduan S, Koppensteiner H, Baeyens A, et al. Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection. Open Biol. 2016;6: pubmed publisher
|
Vickman R, Crist S, Kerian K, Eberlin L, Cooks R, Burcham G, et al. Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer. Mol Cancer Res. 2016;14:776-86 pubmed publisher
|
Fernandez D, Flores Santibáñez F, Neira J, Osorio Barrios F, Tejon G, Nuñez S, et al. Purinergic Signaling as a Regulator of Th17 Cell Plasticity. PLoS ONE. 2016;11:e0157889 pubmed publisher
|
Cao W, Guo J, Wen X, Miao L, Lin F, Xu G, et al. CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation. Nat Commun. 2016;7:11687 pubmed publisher
|
Hickman O, Smith R, Dasgupta P, Rao S, Nayak S, Sreenivasan S, et al. Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2. Br J Cancer. 2016;114:1235-42 pubmed publisher
|
Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph K. Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat Cell Biol. 2016;18:480-90 pubmed publisher
|
O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed publisher
|
Yamamoto H, Lu J, Oba S, Kawamata T, Yoshimi A, Kurosaki N, et al. miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target. Sci Rep. 2016;6:19204 pubmed publisher
|
Satcher R, Pan T, Bilen M, Li X, Lee Y, Ortiz A, et al. Cadherin-11 endocytosis through binding to clathrin promotes cadherin-11-mediated migration in prostate cancer cells. J Cell Sci. 2015;128:4629-41 pubmed publisher
|
Cabet E, Batonnet Pichon S, Delort F, Gausserès B, Vicart P, Lilienbaum A. Antioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of Desminopathy. PLoS ONE. 2015;10:e0137009 pubmed publisher
|
Weiser J, Roche A, Hergott C, LaRose M, Connolly T, Jorgensen W, et al. Macrophage Migration Inhibitory Factor Is Detrimental in Pneumococcal Pneumonia and a Target for Therapeutic Immunomodulation. J Infect Dis. 2015;212:1677-82 pubmed publisher
|
Isobe T, Hisamori S, Hogan D, Zabala M, Hendrickson D, Dalerba P, et al. miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway. elife. 2014;3: pubmed publisher
|
Feng Q, Langereis M, Olagnier D, Chiang C, van de Winkel R, van Essen P, et al. Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation. PLoS ONE. 2014;9:e95927 pubmed publisher
|
Hussain M, Baig S, Neumann S, Peche V, Szczepanski S, Nurnberg G, et al. CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013;22:5199-214 pubmed publisher
|