product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-Bcl-2
catalog :
633502
quantity :
100 μg
price :
218 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BCL/10C4
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1c
Amen A, Loughran R, Huang C, Lew R, Ravi A, Guan Y, et al. Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi. Cell Rep Methods. 2022;2:100239 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3o, 2j
Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2d
Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Chandrasekaran U, Yi W, Gupta S, Weng C, Giannopoulou E, Chinenov Y, et al. Regulation of Effector Treg Cells in Murine Lupus. Arthritis Rheumatol. 2016;68:1454-66 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6c
Metz P, Lopez J, Kim S, Akimoto K, Ohno S, Chang J. Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates. Sci Rep. 2016;6:19182 pubmed publisher
  • western blot; mouse; fig 6
Sochalska M, Ottina E, Tuzlak S, Herzog S, Herold M, Villunger A. Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival. Cell Death Differ. 2016;23:628-39 pubmed publisher
  • flow cytometry; mouse
Vuillefroy de Silly R, Ducimetière L, Yacoub Maroun C, Dietrich P, Derouazi M, Walker P. Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells. Eur J Immunol. 2015;45:2263-75 pubmed publisher
  • flow cytometry; mouse
Singh K, Hjort M, Thorvaldson L, Sandler S. Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naïve mice. Sci Rep. 2015;5:7767 pubmed publisher
Wang H, Chen W, Huang Y, Hsu S, Tsao Y, Hsu Y, et al. Interleukin-20 is involved in dry eye disease and is a potential therapeutic target. J Biomed Sci. 2022;29:36 pubmed publisher
Hailemichael Y, Johnson D, Abdel Wahab N, Foo W, Bentebibel S, Daher M, et al. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022;40:509-523.e6 pubmed publisher
Lai C, Tang C, Fu S, Tseng W, Tseng K. Effects of swimming training on myocardial protection in rats. Biomed Rep. 2022;16:19 pubmed publisher
Su W, Chapman N, Wei J, Zeng H, Dhungana Y, Shi H, et al. Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells. Cell Metab. 2020;32:996-1011.e7 pubmed publisher
Sun Y, Xie J, Anyalebechi J, Chen C, Sun H, Xue M, et al. CD28 Agonism Improves Survival in Immunologically Experienced Septic Mice via IL-10 Released by Foxp3+ Regulatory T Cells. J Immunol. 2020;205:3358-3371 pubmed publisher
Keller H, Kim H, Jo Y, Gress R, Hong C, Park J. The Abundance and Availability of Cytokine Receptor IL-2Rβ (CD122) Constrain the Lymphopenia-Induced Homeostatic Proliferation of Naive CD4 T Cells. J Immunol. 2020;204:3227-3235 pubmed publisher
Kobayashi K, Tsugami Y, Suzuki N, Suzuki T, Nishimura T. Nicotine directly affects milk production in lactating mammary epithelial cells concurrently with inactivation of STAT5 and glucocorticoid receptor in vitro. Toxicol In Vitro. 2020;63:104741 pubmed publisher
Wei S, Sharma R, Anang N, Levine J, Zhao Y, Mancuso J, et al. Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States. Immunity. 2019;50:1084-1098.e10 pubmed publisher
Lee B, Jo Y, Kim G, Ali L, Sohn D, Lee S, et al. Specific Inhibition of Soluble γc Receptor Attenuates Collagen-Induced Arthritis by Modulating the Inflammatory T Cell Responses. Front Immunol. 2019;10:209 pubmed publisher
Sun I, Oh M, Zhao L, Patel C, Arwood M, Xu W, et al. mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells. J Immunol. 2018;201:481-492 pubmed publisher
Tang J, Sun M, Shi G, Xu Y, Han Y, Li X, et al. Toll-Like Receptor 8 Agonist Strengthens the Protective Efficacy of ESAT-6 Immunization to Mycobacterium tuberculosis Infection. Front Immunol. 2017;8:1972 pubmed publisher
Li Z, Zhang S, Wan Y, Cai M, Wang W, Zhu Y, et al. MicroRNA-146a Overexpression Impairs the Positive Selection during T Cell Development. Front Immunol. 2017;8:2006 pubmed publisher
Jain R, Sheridan J, Policheni A, Heinlein M, Gandolfo L, Dewson G, et al. A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood. 2017;130:2504-2515 pubmed publisher
Widjaja C, Olvera J, Metz P, Phan A, Savas J, de Bruin G, et al. Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. J Clin Invest. 2017;127:3609-3623 pubmed publisher
Klann J, Remedios K, Kim S, Metz P, Lopez J, Mack L, et al. Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool. J Immunol. 2017;198:4639-4651 pubmed publisher
Doi K, Fujimoto T, Okamura T, Ogawa M, Tanaka Y, Mototani Y, et al. ZFAT plays critical roles in peripheral T cell homeostasis and its T cell receptor-mediated response. Biochem Biophys Res Commun. 2012;425:107-12 pubmed publisher
Zuber J, Rappaport A, Luo W, Wang E, Chen C, Vaseva A, et al. An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev. 2011;25:1628-40 pubmed publisher
product information
Antigen :
Bcl-2
Apps. Abbrev. :
WB, IP, ICC, IHC-F
Cat # :
633502
Clone :
BCL/10C4
Item :
Purified anti-Bcl-2
Isotype :
Mouse IgG1, κ
Other Names :
B-cell leukemia 2
Size :
100 μg
Price (USD) :
218 USD
Reactivity :
Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
N-terminal, Amino acid residues 61-76 of mouse Bcl-2
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue^4, immunocytochemical staining^5, and immunoprecipitation^5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA