Purified anti-Syk | BioLegend 626201 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-Syk

catalog :

626201

quantity :

25 μg

price :

118 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SYK-01

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 5	Kläsener K, Maity P, Hobeika E, Yang J, Reth M. B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. elife. 2014;3:e02069 pubmed publisher
	Zheng S, Sieder M, Mitterer M, Reth M, Cavallari M, Yang J. A new branched proximity hybridization assay for the quantification of nanoscale protein-protein proximity. PLoS Biol. 2019;17:e3000569 pubmed publisher
	Zhong J, Scholz T, Yau A, Guérard S, Huffmeier U, Burkhardt H, et al. Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes. Sci Adv. 2018;4:eaas9864 pubmed publisher
	Duque Afonso J, Lin C, Han K, Wei M, Feng J, Kurzer J, et al. E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia. Cancer Res. 2016;76:6937-6949 pubmed
	HÃ¼ttl S, KlÃ¤sener K, Schweizer M, Schneppenheim J, Oberg H, Kabelitz D, et al. Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells. J Immunol. 2015;195:1548-63 pubmed publisher
	Hobeika E, Levit Zerdoun E, Anastasopoulou V, Pohlmeyer R, Altmeier S, Alsadeq A, et al. CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. EMBO J. 2015;34:925-39 pubmed publisher
	Alsadeq A, Hobeika E, Medgyesi D, Kläsener K, Reth M. The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling. J Immunol. 2014;193:268-76 pubmed publisher
	Cunningham C, Mills E, Mielke L, O Farrell L, Lavelle E, Mori A, et al. Osteoarthritis-associated basic calcium phosphate crystals induce pro-inflammatory cytokines and damage-associated molecules via activation of Syk and PI3 kinase. Clin Immunol. 2012;144:228-36 pubmed publisher
	Hatterer E, Benon A, Chounlamountri N, Watrin C, Angibaud J, Jouanneau E, et al. Syk kinase is phosphorylated in specific areas of the developing nervous system. Neurosci Res. 2011;70:172-82 pubmed publisher
	Inoue M, Moriwaki Y, Arikawa T, Chen Y, Oh Y, Oliver T, et al. Cutting edge: critical role of intracellular osteopontin in antifungal innate immune responses. J Immunol. 2011;186:19-23 pubmed publisher

product information

Antigen :

Syk

Apps. Abbrev. :

WB, IHC-P, IP

Cat # :

626201

Clone :

SYK-01

Item :

Purified anti-Syk

Isotype :

Mouse IgG1, κ

Other Names :

Spleen tyrosine kinase, protein tyrosine kinase SYK

Size :

25 μg

Price (USD) :

118 USD

Reactivity :

Human, Rat, Mouse

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Partial recombinant (amino acids 5-360) human Syk

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation.This clone may produce a non-specific band of roughly about 250 kD at higher antibody concentrationsThis clone does not recognize ZAP70This clone has been reported to recognize rat Syk;

more info or order :

BioLegend product webpage