product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-β-Actin
catalog :
622101
quantity :
50 μL
price :
118 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Poly6221
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 40
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1
Peteranderl C, Morales Nebreda L, Selvakumar B, Lecuona E, Vadász I, Morty R, et al. Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection. J Clin Invest. 2016;126:1566-80 pubmed publisher
Nishina T, Deguchi Y, Kawauchi M, Xiyu C, Yamazaki S, Mikami T, et al. Interleukin 11 confers resistance to dextran sulfate sodium-induced colitis in mice. iScience. 2023;26:105934 pubmed publisher
Shibata K, Motozono C, Nagae M, Shimizu T, Ishikawa E, Motooka D, et al. Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b. Nat Commun. 2022;13:6948 pubmed publisher
Mete B, Pekbilir E, Bilge B, Georgiadou P, Celik E, Sutlu T, et al. Human immunodeficiency virus type 1 impairs sumoylation. Life Sci Alliance. 2022;5: pubmed publisher
Ergünay T, Ayhan O, Celen A, Georgiadou P, Pekbilir E, Abaci Y, et al. Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding. Life Sci Alliance. 2022;5: pubmed publisher
Kartika I, Kotani H, Iida Y, Koyanagi A, Tanino R, Harada M. Protective role of cytoplasmic p21Cip1/Waf1 in apoptosis of CDK4/6 inhibitor-induced senescence in breast cancer cells. Cancer Med. 2021;10:8988-8999 pubmed publisher
Pototskiy E, Vinokuroff K, Ojeda A, Major C, Sharma D, Anderson T, et al. Downregulation of CD40L-CD40 attenuates seizure susceptibility and severity of seizures. Sci Rep. 2021;11:17262 pubmed publisher
Man F, Nadkarni S, Kanabar V, E Lacerda R, Gomes Ferreira S, Federici Canova D, et al. A peptide derived from chaperonin 60.1, IRL201104, inhibits LPS-induced acute lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2021;321:L803-L813 pubmed publisher
Fliegauf M, Kr xfc ger R, Steiner S, Hanitsch L, B xfc chel S, Wahn V, et al. A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage. Front Immunol. 2021;12:621503 pubmed publisher
Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, et al. Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer. Nat Commun. 2021;12:2281 pubmed publisher
Wakatsuki S, Takahashi Y, Shibata M, Adachi N, Numakawa T, Kunugi H, et al. Small noncoding vault RNA modulates synapse formation by amplifying MAPK signaling. J Cell Biol. 2021;220: pubmed publisher
Beker M, K x131 l x131 xe7 E. The role of circadian rhythm in the regulation of cellular protein profiles in the brain. Turk J Med Sci. 2021;51:2705-2715 pubmed publisher
Pfeil E, Brands J, Merten N, Vögtle T, Vescovo M, Rick U, et al. Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs. Mol Cell. 2020;80:940-954.e6 pubmed publisher
Okimoto T, Kotani H, Iida Y, Koyanagi A, Tanino R, Tsubata Y, et al. Pemetrexed sensitizes human lung cancer cells to cytotoxic immune cells. Cancer Sci. 2020;111:1910-1920 pubmed publisher
Tao H, Chen K, Wang X, Chen B, Zhao W, Zheng Y, et al. CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism. Front Immunol. 2020;11:148 pubmed publisher
Muri J, Thut H, Feng Q, Kopf M. Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip. elife. 2020;9: pubmed publisher
Taha A, Sharifpanah F, Wartenberg M, Sauer H. Omega-3 and Omega-6 polyunsaturated fatty acids stimulate vascular differentiation of mouse embryonic stem cells. J Cell Physiol. 2020;235:7094-7106 pubmed publisher
Berdasco C, Duhalde Vega M, Rosato Siri M, Goldstein J. Environmental Cues Modulate Microglial Cell Behavior Upon Shiga Toxin 2 From Enterohemorrhagic Escherichia coli Exposure. Front Cell Infect Microbiol. 2019;9:442 pubmed publisher
Agabiti S, Li J, Dong W, Poe M, Wiemer A. Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition. Cell Death Dis. 2019;10:733 pubmed publisher
Feddersen C, Schillo J, Varzavand A, Vaughn H, Wadsworth L, Voigt A, et al. Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma. Cancer Res. 2019;79:5074-5087 pubmed publisher
Che L, Li Y, Song R, Qin C, Hao W, Wang B, et al. Anti-inflammatory and anti-apoptosis activity of taraxasterol in ulcerative colitis in vitro and in vivo. Exp Ther Med. 2019;18:1745-1751 pubmed publisher
Inao T, Kotani H, Iida Y, Kartika I, Okimoto T, Tanino R, et al. Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity. Cancer Sci. 2019;110:2690-2699 pubmed publisher
Tsurusaki S, Tsuchiya Y, Koumura T, Nakasone M, Sakamoto T, Matsuoka M, et al. Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis. Cell Death Dis. 2019;10:449 pubmed publisher
Kumarasinghe N, Moss W. Analysis of a structured intronic region of the LMP2 pre-mRNA from EBV reveals associations with human regulatory proteins and nuclear actin. BMC Res Notes. 2019;12:33 pubmed publisher
Shepardson K, Larson K, Johns L, Stanek K, Cho H, Wellham J, et al. IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections. Front Immunol. 2018;9:2589 pubmed publisher
Al Naggar I, Hardy C, Taweh O, Grabauskas T, Mulkey D, Kuchel G, et al. HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. J Gerontol A Biol Sci Med Sci. 2019;74:325-329 pubmed publisher
Merten N, Fischer J, Simon K, Zhang L, Schröder R, Peters L, et al. Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation. Cell Chem Biol. 2018;25:775-786.e5 pubmed publisher
Wang D, Diao H, Getzler A, Rogal W, Frederick M, Milner J, et al. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 2018;48:659-674.e6 pubmed publisher
Zheng X, Kang W, Liu H, Guo S. Inhibition effects of total flavonoids from Sculellaria barbata D. Don on human breast carcinoma bone metastasis via downregulating PTHrP pathway. Int J Mol Med. 2018;41:3137-3146 pubmed publisher
Grundmann M, Merten N, Malfacini D, Inoue A, Preis P, Simon K, et al. Lack of beta-arrestin signaling in the absence of active G proteins. Nat Commun. 2018;9:341 pubmed publisher
Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, et al. Tanshinones that selectively block the collagenase activity of cathepsin K provide a novel class of ectosteric antiresorptive agents for bone. Br J Pharmacol. 2018;175:902-923 pubmed publisher
Zhu S, Zhang X, Weichert Leahey N, Dong Z, Zhang C, Lopez G, et al. LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 2017;32:310-323.e5 pubmed publisher
Naneix F, Tantot F, Glangetas C, Kaufling J, Janthakhin Y, Boitard C, et al. Impact of Early Consumption of High-Fat Diet on the Mesolimbic Dopaminergic System. Eneuro. 2017;4: pubmed publisher
Agabiti S, Li J, Wiemer A. Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation. Cell Death Dis. 2017;8:e2678 pubmed publisher
Takeda K, Nakayama M, Hayakawa Y, Kojima Y, Ikeda H, Imai N, et al. IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting. Nat Commun. 2017;8:14607 pubmed publisher
Wakatsuki S, Tokunaga S, Shibata M, Araki T. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. J Cell Biol. 2017;216:477-493 pubmed publisher
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Wakatsuki S, Furuno A, Ohshima M, Araki T. Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration. J Cell Biol. 2015;211:881-96 pubmed publisher
Hua X, Yuan X, Li Z, Coursey T, Pflugfelder S, Li D. A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins. PLoS ONE. 2015;10:e0128039 pubmed publisher
product information
Antigen :
beta-actin
Apps. Abbrev. :
WB, ICC, IHC-P
Cat # :
622101
Clone :
Poly6221
Item :
Purified anti-β-Actin
Isotype :
Rabbit Polyclonal IgG
Other Names :
Actin, cytoplasmic 1
Size :
50 μL
Price (USD) :
118 USD
Reactivity :
Mouse, Rat, Human
Clonality :
Polyclonal
Host :
Rabbit
Conjugate/Tag/Label :
PURE
Immunogen :
Peptide-KLH, NH2 terminus
Application Notes :
This product may contain other non-IgG subtypes.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA