product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-p63 (ΔN)
catalog :
619002
quantity :
200 μL
price :
411 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Poly6190
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 55
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 0.5 ug/ml; loading ...; fig 3a
Bandeira F, Goh T, Setiawan M, Yam G, Mehta J. Cellular therapy of corneal epithelial defect by adipose mesenchymal stem cell-derived epithelial progenitors. Stem Cell Res Ther. 2020;11:14 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
Noda K, Mishina Y, Komatsu Y. Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice. Dev Biol. 2016;415:306-313 pubmed publisher
Saraswathula A, Liu M, Kulaga H, Lane A. Chronic interleukin-13 expression in mouse olfactory mucosa results in regional aneuronal epithelium. Int Forum Allergy Rhinol. 2023;13:230-241 pubmed publisher
Weiner A, Zhao G, Zayas H, Holcomb N, Adams Tzivelekidis S, Wong J, et al. ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury. Cell Rep. 2022;41:111805 pubmed publisher
Hernandez B, Cain M, Lynch A, Flores J, Tuvim M, Dickey B, et al. Intermediary Role of Lung Alveolar Type 1 Cells in Epithelial Repair upon Sendai Virus Infection. Am J Respir Cell Mol Biol. 2022;67:389-401 pubmed publisher
Mao X, Xiong Z, Xue H, Brown M, Gete Y, Yu R, et al. Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome. Int J Mol Sci. 2022;23: pubmed publisher
Teng T, Teng C, Kaartinen V, Bush J. A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis. Development. 2022;149: pubmed publisher
Napoli M, Wu S, Gore B, Abbas H, Lee K, Checker R, et al. ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer. Nat Commun. 2022;13:614 pubmed publisher
Portal C, Wang Z, Scott D, Wolosin J, Iomini C. The c-Myc Oncogene Maintains Corneal Epithelial Architecture at Homeostasis, Modulates p63 Expression, and Enhances Proliferation During Tissue Repair. Invest Ophthalmol Vis Sci. 2022;63:3 pubmed publisher
Ngan S, Quach H, Laselva O, Huang E, Mangos M, Xia S, et al. Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function. Curr Protoc. 2022;2:e341 pubmed publisher
Meuser M, Deuper L, Rudat C, Aydo x11f du N, Thiesler H, Zarnovican P, et al. FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022;149: pubmed publisher
Zhuang L, Visalakshan R, Kaur P. Dermal Pericytes Exhibit Declined Ability to Promote Human Skin Regeneration with Ageing in 3D Organotypic Culture Models. Cells. 2021;10: pubmed publisher
Van Sciver N, Ohashi M, Nawandar D, Pauly N, Lee D, Makielski K, et al. ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells. PLoS Pathog. 2021;17:e1010045 pubmed publisher
Ruiz E, Pinto Fernandez A, Turnbull A, Lan L, Charlton T, Scott H, et al. USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma. elife. 2021;10: pubmed publisher
Larsen S, Cowley C, Sajjath S, Barrows D, Yang Y, Carroll T, et al. Establishment, maintenance, and recall of inflammatory memory. Cell Stem Cell. 2021;: pubmed publisher
Goering J, Wenger L, Stetsiv M, Moedritzer M, Hall E, Isai D, et al. In-frame deletion of SPECC1L microtubule association domain results in gain-of-function phenotypes affecting embryonic tissue movement and fusion events. Hum Mol Genet. 2021;31:18-31 pubmed publisher
Wu H, Wang B, Armstrong S, Abuetabh Y, Leng S, Roa W, et al. Hsp70 acts as a fine-switch that controls E3 ligase CHIP-mediated TAp63 and ΔNp63 ubiquitination and degradation. Nucleic Acids Res. 2021;49:2740-2758 pubmed publisher
Li M, Huang H, Li L, He C, Zhu L, Guo H, et al. Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis. Nat Commun. 2021;12:420 pubmed publisher
Li M, Zhu L, Liu J, Huang H, Guo H, Wang L, et al. Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis. Signal Transduct Target Ther. 2021;6:5 pubmed publisher
Crowley L, Cambuli F, Aparicio L, Shibata M, Robinson B, Xuan S, et al. A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors. elife. 2020;9: pubmed publisher
Böttinger P, Schreiber K, Hyjek E, Krausz T, Spiotto M, Steiner M, et al. Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens. Carcinogenesis. 2020;41:1605-1615 pubmed publisher
Yuan T, Klinkhammer K, Lyu H, Gao S, Yuan J, Hopkins S, et al. Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration. Front Pharmacol. 2020;11:120 pubmed publisher
Christians A, Weiss A, Martens H, Klopf M, Hennies I, Haffner D, et al. Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020;29:1192-1204 pubmed publisher
Marsh T, Kenific C, Suresh D, Gonzalez H, Shamir E, Mei W, et al. Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression. Dev Cell. 2020;52:591-604.e6 pubmed publisher
Zhang B, Ci X, Tao R, Ni J, Xuan X, King J, et al. Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration. Nat Commun. 2020;11:997 pubmed publisher
Kim J, Fei L, Yin W, Coquenlorge S, Rao Bhatia A, Zhang X, et al. Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun. 2020;11:334 pubmed publisher
Hall E, Wenger L, Wilson N, Undurty Akella S, Standley J, Augustine Akpan E, et al. SPECC1L regulates palate development downstream of IRF6. Hum Mol Genet. 2020;29:845-858 pubmed publisher
Uchtmann K, Taylor J, Timms B, Stahlhut R, Ricke E, Ellersieck M, et al. Fetal bisphenol A and ethinylestradiol exposure alters male rat urogenital tract morphology at birth: Confirmation of prior low-dose findings in CLARITY-BPA. Reprod Toxicol. 2020;91:131-141 pubmed publisher
Chen M, Reed R, Lane A. Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense. Cell Stem Cell. 2019;25:501-513.e5 pubmed publisher
Crowell P, Fox J, Hashimoto T, Diaz J, Navarro H, Henry G, et al. Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep. 2019;28:1499-1510.e6 pubmed publisher
Masterton S, Ahearne M. The Effect of Calcium and Glucose Concentration on Corneal Epithelial Cell Lines Differentiation, Proliferation, and Focal Adhesion Expression. Biores Open Access. 2019;8:74-83 pubmed publisher
Hegde G, de la Cruz C, Giltnane J, Crocker L, Venkatanarayan A, Schaefer G, et al. NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma. elife. 2019;8: pubmed publisher
Karsli Uzunbas G, Ahmed F, Sammons M. Control of p53-dependent transcription and enhancer activity by the p53 family member p63. J Biol Chem. 2019;294:10720-10736 pubmed publisher
Chen H, Poran A, Unni A, Huang S, Elemento O, Snoeck H, et al. Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med. 2019;216:674-687 pubmed publisher
Aydoğdu N, Rudat C, Trowe M, Kaiser M, Lüdtke T, Taketo M, et al. TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018;145: pubmed publisher
Lu Y, Cao J, Napoli M, Xia Z, Zhao N, Creighton C, et al. miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem Cells. 2018;36:1875-1889 pubmed publisher
D Amico S, Shi J, Martin B, Crawford H, Petrenko O, Reich N. STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis. Genes Dev. 2018;32:1175-1187 pubmed publisher
Li J, Yuan Y, He J, Feng J, Han X, Jing J, et al. Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion. Dev Biol. 2018;441:191-203 pubmed publisher
Geyer F, Li A, Papanastasiou A, Smith A, Selenica P, Burke K, et al. Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas. Nat Commun. 2018;9:1816 pubmed publisher
Wang Z, Plasschaert L, Aryal S, Renaud N, Yang Z, Choo Wing R, et al. TRRAP is a central regulator of human multiciliated cell formation. J Cell Biol. 2018;217:1941-1955 pubmed publisher
Lin Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson C, et al. KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis. Genes Dev. 2018;32:181-193 pubmed publisher
Assmus A, Mansley M, Mullins L, Peter A, Mullins J. mCCDcl1 cells show plasticity consistent with the ability to transition between principal and intercalated cells. Am J Physiol Renal Physiol. 2018;314:F820-F831 pubmed publisher
Langa P, Wardowska A, Zielinski J, Podolak Popinigis J, Sass P, Sosnowski P, et al. Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds. J Dermatol Sci. 2018;89:272-281 pubmed publisher
Hazawa M, Lin D, Kobayashi A, Jiang Y, Xu L, Dewi F, et al. ROCK-dependent phosphorylation of NUP62 regulates p63 nuclear transport and squamous cell carcinoma proliferation. EMBO Rep. 2018;19:73-88 pubmed publisher
Abbas H, Bui N, Rajapakshe K, Wong J, Gunaratne P, Tsai K, et al. Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes. Cancer Res. 2018;78:451-462 pubmed publisher
Volckaert T, Yuan T, Chao C, Bell H, Sitaula A, Szimmtenings L, et al. Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells. Dev Cell. 2017;43:48-59.e5 pubmed publisher
Li Y, Kong F, Shao Q, Wang R, Hu E, Liu J, et al. YAP Expression and Activity Are Suppressed by S100A7 via p65/NF?B-mediated Repression of ?Np63. Mol Cancer Res. 2017;15:1752-1763 pubmed publisher
Traver G, Mont S, Gius D, Lawson W, Ding G, Sekhar K, et al. Loss of Nrf2 promotes alveolar type 2 cell loss in irradiated, fibrotic lung. Free Radic Biol Med. 2017;112:578-586 pubmed publisher
Bohnenpoll T, Wittern A, Mamo T, Weiss A, Rudat C, Kleppa M, et al. A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017;13:e1006951 pubmed publisher
Mamo T, Wittern A, Kleppa M, Bohnenpoll T, Weiss A, Kispert A. BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017;26:3553-3563 pubmed publisher
Bohnenpoll T, Feraric S, Nattkemper M, Weiss A, Rudat C, Meuser M, et al. Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017;28:1792-1801 pubmed publisher
Rode I, Martins V, Küblbeck G, Maltry N, Tessmer C, Rodewald H. Foxn1 Protein Expression in the Developing, Aging, and Regenerating Thymus. J Immunol. 2015;195:5678-87 pubmed publisher
Ahronian L, Driscoll D, Klimstra D, Lewis B. The p53R172H mutant does not enhance hepatocellular carcinoma development and progression. PLoS ONE. 2015;10:e0123816 pubmed publisher
Curtis K, Aenlle K, Frisch R, Howard G. TAp63γ and ΔNp63β promote osteoblastic differentiation of human mesenchymal stem cells: regulation by vitamin D3 Metabolites. PLoS ONE. 2015;10:e0123642 pubmed publisher
Stewart R, Sheridan C, Hiscott P, Czanner G, Kaye S. Human Conjunctival Stem Cells are Predominantly Located in the Medial Canthal and Inferior Forniceal Areas. Invest Ophthalmol Vis Sci. 2015;56:2021-30 pubmed publisher
product information
Antigen :
p63
Apps. Abbrev. :
WB, IHC
Cat # :
619002
Clone :
Poly6190
Item :
Purified anti-p63 (ΔN)
Isotype :
Rabbit Polyclonal IgG
Other Names :
p63, δN p63-α, -β, -γ
Size :
200 μL
Price (USD) :
411 USD
Reactivity :
Human
Clonality :
Polyclonal
Host :
Rabbit
Conjugate/Tag/Label :
PURE
Immunogen :
Modified peptide
Application Notes :
This product may contain other non-IgG subtypes.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA