This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-Mcl-1
catalog :
613601
quantity :
50 μl
price :
75 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
Poly6136
reactivity :
human, mouse
application :
western blot
citations: 8
Reference
Peperzak V, Veraar E, Keller A, Xiao Y, Borst J. The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation. J Immunol. 2010;185:6670-8 pubmed publisher
Baumgartner C, Yagita H, Malherbe L. A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination. J Immunol. 2012;189:2309-17 pubmed publisher
Zhao Y, Altman B, Coloff J, Herman C, Jacobs S, Wieman H, et al. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol. 2007;27:4328-39 pubmed
Fedorchenko O, Stiefelhagen M, Peer-Zada A, Barthel R, Mayer P, Eckei L, et al. CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood. 2013;121:4126-36 pubmed publisher
Hu L, Chen L, Li L, Sun H, Yang G, Chang Y, et al. Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1. J Virol. 2011;85:3214-28 pubmed publisher
Zhang Y, Wang Z, Magnuson N. Pim-1 kinase-dependent phosphorylation of p21Cip1/WAF1 regulates its stability and cellular localization in H1299 cells. Mol Cancer Res. 2007;5:909-22 pubmed
Takezaki S, Yamada M, Kato M, Park M, Maruyama K, Yamazaki Y, et al. Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain. J Immunol. 2012;189:1521-6 pubmed publisher
Coloff J, Mason E, Altman B, Gerriets V, Liu T, Nichols A, et al. Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells. J Biol Chem. 2011;286:5921-33 pubmed publisher
product information
Antigen :
Mcl-1
Apps. Abbrev. :
Western Blotting
Cat # :
613601
Clone :
Poly6136
Item :
Purified anti-Mcl-1
Isotype :
Rabbit Polyclonal IgG
Other Names :
Myeloid cell leukemia-1
Size :
50 μl
Price (USD) :
75 USD
Reactivity :
Mouse, Human
Clonality :
Polyclonal
Host :
Rabbit
Conjugate/Tag/Label :
PURE
Immunogen :
Full length recombinant protein
PubMed ID :
17371841,21048108,21159778,21228225,22844120
company information
BioLegend
9727 Pacific Heights Blvd.
San Diego, CA 92121
customerserv@biolegend.com
www.biolegend.com
headquarters: USA