product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-H2A.X Phospho (Ser139)
catalog :
613404
quantity :
100 tests
price :
340 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
2F3
reactivity :
human, mouse
application :
immunocytochemistry
more info or order :
citations: 18
Reference
Sugitani N, Vendetti F, Cipriano A, Pandya P, Deppas J, Moiseeva T, et al. Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression. Cell Rep. 2022;40:111371 pubmed publisher
Chang Y, Ignatova D, Hoetzenecker W, Pascolo S, Fassnacht C, Guenova E. Increased Chlormethine-Induced DNA Double-Stranded Breaks in Malignant T Cells from Mycosis Fungoides Skin Lesions. JID Innov. 2022;2:100069 pubmed publisher
Zhang W, Ma Q, Long B, Sun Z, Liu L, Lin D, et al. Runt-Related Transcription Factor 3 Promotes Acute Myeloid Leukemia Progression. Front Oncol. 2021;11:725336 pubmed publisher
Liu J, Hormuth D, Davis T, Yang J, McKenna M, Jarrett A, et al. A time-resolved experimental-mathematical model for predicting the response of glioma cells to single-dose radiation therapy. Integr Biol (Camb). 2021;13:167-183 pubmed publisher
Liu Z, Dong X, Cao Z, Qiu S, Li Y, Zhong M, et al. Mutant U2AF1-induced differential alternative splicing causes an oxidative stress in bone marrow stromal cells. Exp Biol Med (Maywood). 2021;246:1750-1759 pubmed publisher
Young K, Eudy E, Bell R, Loberg M, Stearns T, Sharma D, et al. Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging. Cell Stem Cell. 2021;28:1473-1482.e7 pubmed publisher
Sarkar A, Gandhi V. Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies. Mol Cell Biochem. 2021;476:417-423 pubmed publisher
Chen Z, Chen C, Zhou T, Duan C, Wang Q, Zhou X, et al. A high-throughput drug combination screen identifies an anti-glioma synergism between TH588 and PI3K inhibitors. Cancer Cell Int. 2020;20:337 pubmed publisher
Shibamoto M, Higo T, Naito A, Nakagawa A, Sumida T, Okada K, et al. Activation of DNA Damage Response and Cellular Senescence in Cardiac Fibroblasts Limit Cardiac Fibrosis After Myocardial Infarction. Int Heart J. 2019;60:944-957 pubmed publisher
Zuazo M, Arasanz H, Fernández Hinojal G, García Granda M, Gato M, Bocanegra A, et al. Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy. EMBO Mol Med. 2019;: pubmed publisher
Han Y, Chen M, Wang H, Hsu J, Li C, Chu Y, et al. Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells. Am J Cancer Res. 2019;9:608-618 pubmed
Chen J, Li N, Yin Y, Zheng N, Min M, Lin B, et al. Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells. Cell Rep. 2018;25:3393-3404.e6 pubmed publisher
Caruso L, Martin K, Lauretti E, Hulse M, Siciliano M, Lupey Green L, et al. Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage. Oncotarget. 2018;9:10585-10605 pubmed publisher
Mitroulis I, Ruppova K, Wang B, Chen L, Grzybek M, Grinenko T, et al. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. 2018;172:147-161.e12 pubmed publisher
Scheffel M, Scurti G, Simms P, Garrett Mayer E, Mehrotra S, Nishimura M, et al. Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death. Cancer Res. 2016;76:6006-6016 pubmed
Namas R, Renauer P, Ognenovski M, Tsou P, Sawalha A. Histone H2AX phosphorylation as a measure of DNA double-strand breaks and a marker of environmental stress and disease activity in lupus. Lupus Sci Med. 2016;3:e000148 pubmed publisher
Smart D, Lynch A. Evaluating the genotoxicity of topoisomerase-targeted antibiotics. Mutagenesis. 2012;27:359-65 pubmed publisher
Smart D, Ahmedi K, Harvey J, Lynch A. Genotoxicity screening via the ?H2AX by flow assay. Mutat Res. 2011;715:25-31 pubmed publisher
product information
Antigen :
H2A.X Phospho Ser139
Apps. Abbrev. :
ICFC
Cat # :
613404
Clone :
2F3
Item :
FITC anti-H2A.X Phospho (Ser139)
Isotype :
Mouse IgG1, κ
Other Names :
H2A.x, H2a/x, Histone 2A, Histone 2A.X, Gamma-H2AX
Size :
100 tests
Price (USD) :
340 USD
Reactivity :
Human, Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Immunogen :
Modified peptide
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA