Published Application/Species/Sample/Dilution | Reference |
---|
- flow cytometry; human; loading ...
| Warnes G. Flow cytometric detection of hyper-polarized mitochondria in regulated and accidental cell death processes. Apoptosis. 2020;25:548-557 pubmed publisher
|
- immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4b
| Okawa A, Morioka T, Imaoka T, Kakinuma S, Matsumoto Y. Differential expression of DNA-dependent protein kinase catalytic subunit in the brain of neonatal mice and young adult mice. Proc Jpn Acad Ser B Phys Biol Sci. 2020;96:171-179 pubmed publisher
|
- immunohistochemistry - paraffin section; Tetrahymena thermophila; 1:200; loading ...; fig 2a
| Tian M, Loidl J. A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation. Nucleic Acids Res. 2018;46:11822-11834 pubmed publisher
|
- immunohistochemistry - paraffin section; mouse; 1:100; tbl 1
| Fu C, Begum K, Jordan P, He Y, Overbeek P. Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS ONE. 2016;11:e0159800 pubmed publisher
|
- immunocytochemistry; mouse
| Bravo M, Nicolini F, Starowicz K, Barroso S, Calés C, Aguilera A, et al. Polycomb RING1A- and RING1B-dependent histone H2A monoubiquitylation at pericentromeric regions promotes S-phase progression. J Cell Sci. 2015;128:3660-71 pubmed publisher
|
- immunocytochemistry; human; 1:500; fig 1
| Maya Mendoza A, Ostrakova J, Kosar M, Hall A, Duskova P, Mistrik M, et al. Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress. Mol Oncol. 2015;9:601-16 pubmed publisher
|
- immunohistochemistry - paraffin section; mouse; 1:500
| Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, et al. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model. Thyroid. 2014;24:502-10 pubmed publisher
|
| Sáez Ayala M, Hoffer L, Abel S, Ben Yaala K, Sicard B, Andrieu G, et al. From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun. 2023;14:3079 pubmed publisher
|
| Roggan M, Kronenberg J, Wollert E, Hoffmann S, Nisar H, Konda B, et al. Unraveling astrocyte behavior in the space brain: Radiation response of primary astrocytes. Front Public Health. 2023;11:1063250 pubmed publisher
|
| Marchena Cruz E, Camino L, Bhandari J, Silva S, Marqueta Gracia J, Amdeen S, et al. DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops. Cell Rep. 2023;42:112148 pubmed publisher
|
| Oelschl xe4 ger L, Stahl P, Kaschani F, Stauber R, Knauer S, Hensel A. Taspase1 Facilitates Topoisomerase IIβ-Mediated DNA Double-Strand Breaks Driving Estrogen-Induced Transcription. Cells. 2023;12: pubmed publisher
|
| Mendoza Munoz P, Gavande N, VanderVere Carozza P, Pawelczak K, Dynlacht J, Garrett J, et al. Ku-DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks. NAR Cancer. 2023;5:zcad003 pubmed publisher
|
| Hsiao H, Yang C, Masai H. Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses. Biomolecules. 2023;13: pubmed publisher
|
| Xu C, Cheng S, Chen K, Song Q, Liu C, Fan C, et al. Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity. Cell Mol Gastroenterol Hepatol. 2023;15:327-354 pubmed publisher
|
| Furia L, Pelicci S, Perillo F, Bolognesi M, Pelicci P, Facciotti F, et al. Automated multimodal fluorescence microscopy for hyperplex spatial-proteomics: Coupling microfluidic-based immunofluorescence to high resolution, high sensitivity, three-dimensional analysis of histological slides. Front Oncol. 2022;12:960734 pubmed publisher
|
| Furia L, Pelicci S, Scanarini M, Pelicci P, Faretta M. From Double-Strand Break Recognition to Cell-Cycle Checkpoint Activation: High Content and Resolution Image Cytometry Unmasks 53BP1 Multiple Roles in DNA Damage Response and p53 Action. Int J Mol Sci. 2022;23: pubmed publisher
|
| Schneider M, Gibson B, Otsuka S, Spicer M, Petrovic M, Blaukopf C, et al. A mitotic chromatin phase transition prevents perforation by microtubules. Nature. 2022;609:183-190 pubmed publisher
|
| Guo Y, Chomiak A, Hong Y, Lowe C, Kopsidas C, Chan W, et al. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration. iScience. 2022;25:104519 pubmed publisher
|
| Ueno H, Hoshino T, Yano W, Tsukioka S, Suzuki T, Hara S, et al. TAS1553, a small molecule subunit interaction inhibitor of ribonucleotide reductase, exhibits antitumor activity by causing DNA replication stress. Commun Biol. 2022;5:571 pubmed publisher
|
| Chomiak A, Guo Y, Kopsidas C, McDaniel D, Lowe C, Pan H, et al. Nde1 is required for heterochromatin compaction and stability in neocortical neurons. iScience. 2022;25:104354 pubmed publisher
|
| Kulbay M, Johnson B, Ricaud G, S xe9 guin Grignon M, Bernier J. Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells. Mol Cell Biochem. 2022;477:2213-2233 pubmed publisher
|
| Ganan Gomez I, Yang H, Ma F, Montalban Bravo G, Thongon N, Marchica V, et al. Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. Nat Med. 2022;28:557-567 pubmed publisher
|
| Pelicci S, Furia L, Scanarini M, Pelicci P, Lanzano L, Faretta M. Novel Tools to Measure Single Molecules Colocalization in Fluorescence Nanoscopy by Image Cross Correlation Spectroscopy. Nanomaterials (Basel). 2022;12: pubmed publisher
|
| Switonski P, Delaney J, Bartelt L, Niu C, Ramos Zapatero M, Spann N, et al. Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7. Cell Rep. 2021;37:110062 pubmed publisher
|
| Lee S, Islam M, Boostanpour K, Aran D, Jin G, Christenson S, et al. Molecular programs of fibrotic change in aging human lung. Nat Commun. 2021;12:6309 pubmed publisher
|
| Denoth Lippuner A, Jaeger B, Liang T, Royall L, Chie S, Buthey K, et al. Visualization of individual cell division history in complex tissues using iCOUNT. Cell Stem Cell. 2021;28:2020-2034.e12 pubmed publisher
|
| Kychygina A, Dall Osto M, Allen J, Cadoret J, Piras V, Pickett H, et al. Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools. Sci Rep. 2021;11:13195 pubmed publisher
|
| Lezaja A, Panagopoulos A, Wen Y, Carvalho E, Imhof R, Altmeyer M. RPA shields inherited DNA lesions for post-mitotic DNA synthesis. Nat Commun. 2021;12:3827 pubmed publisher
|
| Callender L, Schroth J, Carroll E, Garrod Ketchley C, Romano L, Hendy E, et al. GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage. Nat Commun. 2021;12:3379 pubmed publisher
|
| Jelínková S, Sleiman Y, Fojtik P, Aimond F, Finan A, Hugon G, et al. Dystrophin Deficiency Causes Progressive Depletion of Cardiovascular Progenitor Cells in the Heart. Int J Mol Sci. 2021;22: pubmed publisher
|
| Sakata R, Niwa K, Ugarte La Torre D, Gu C, Tahara E, Takada S, et al. Opening of cohesin's SMC ring is essential for timely DNA replication and DNA loop formation. Cell Rep. 2021;35:108999 pubmed publisher
|
| Michelena J, Pellegrino S, Spegg V, Altmeyer M. Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and BRCA1-deficient cells. Life Sci Alliance. 2021;4: pubmed publisher
|
| Oshima K, Zhao J, Pérez Durán P, Brown J, Patiño Galindo J, Chu T, et al. Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia. Nat Cancer. 2020;1:1113-1127 pubmed publisher
|
| Amrenova A, Suzuki K, Saenko V, Yamashita S, Mitsutake N. Cell competition between anaplastic thyroid cancer and normal thyroid follicular cells exerts reciprocal stress response defining tumor suppressive effects of normal epithelial tissue. PLoS ONE. 2021;16:e0249059 pubmed publisher
|
| Roeschert I, Poon E, Henssen A, Garcia H, Gatti M, Giansanti C, et al. Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma. Nat Cancer. 2021;2:312-326 pubmed publisher
|
| Swift M, Beishline K, Flashner S, Azizkhan Clifford J. DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1. Cell Rep. 2021;34:108840 pubmed publisher
|
| Nomura D, Abe R, Tsukimoto M. Involvement of TRPM8 Channel in Radiation-Induced DNA Damage Repair Mechanism Contributing to Radioresistance of B16 Melanoma. Biol Pharm Bull. 2021;44:642-652 pubmed publisher
|
| Cuella Martin R, Hayward S, Fan X, Chen X, Huang J, Taglialatela A, et al. Functional interrogation of DNA damage response variants with base editing screens. Cell. 2021;184:1081-1097.e19 pubmed publisher
|
| Kim C, Sung S, Kim J, Lee H, Jung Y, Shin S, et al. Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells. Nat Commun. 2021;12:1097 pubmed publisher
|
| Murray Nerger L, Justice J, Rekapalli P, Hutton J, Cristea I. Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res. 2021;: pubmed publisher
|
| Suzuki T, Katada E, Mizuoka Y, Takagi S, Kazuki Y, Oshimura M, et al. A novel all-in-one conditional knockout system uncovered an essential role of DDX1 in ribosomal RNA processing. Nucleic Acids Res. 2021;: pubmed publisher
|
| Hopp A, Teloni F, Bisceglie L, Gondrand C, Raith F, Nowak K, et al. Mitochondrial NAD+ Controls Nuclear ARTD1-Induced ADP-Ribosylation. Mol Cell. 2021;81:340-354.e5 pubmed publisher
|
| Wang R, Lenoir W, Wang C, Su D, McLaughlin M, Hu Q, et al. DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress. Proc Natl Acad Sci U S A. 2020;117:33436-33445 pubmed publisher
|
| Gavande N, VanderVere Carozza P, Pawelczak K, Mendoza Munoz P, Vernon T, HANAKAHI L, et al. Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku-DNA interaction. Nucleic Acids Res. 2020;48:11536-11550 pubmed publisher
|
| Xu Y, Lin Y, Luo Y, Yang Y, Long B, Fang Z, et al. RAD52 aptamer regulates DNA damage repair and STAT3 in BRCA1/BRCA2‑deficient human acute myeloid leukemia. Oncol Rep. 2020;44:1455-1466 pubmed publisher
|
| Prendergast L, McClurg U, Hristova R, Berlinguer Palmini R, Greener S, Veitch K, et al. Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability. Nat Commun. 2020;11:4534 pubmed publisher
|
| Wang C, Chen Z, Su D, Tang M, Nie L, Zhang H, et al. C17orf53 is identified as a novel gene involved in inter-strand crosslink repair. DNA Repair (Amst). 2020;95:102946 pubmed publisher
|
| Gatti M, Imhof R, Huang Q, Baudis M, Altmeyer M. The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency. Cell Rep. 2020;32:107985 pubmed publisher
|
| Mlcochova P, Winstone H, Zuliani Alvarez L, Gupta R. TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages. Cell Rep. 2020;30:3972-3980.e5 pubmed publisher
|
| Kim I, Rao G, Zhao X, Fan R, Avantaggiati M, Wang Y, et al. Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells. Cell Death Differ. 2020;27:2263-2279 pubmed publisher
|
| Delaney J, Patel C, Bapat J, Jones C, Ramos Zapatero M, Ortell K, et al. Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLoS Genet. 2020;16:e1008558 pubmed publisher
|
| Stobezki R, Titus S, Halicka D, Darzynkiewicz Z, Oktay K. Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. Reprod Sci. 2020;27:940-953 pubmed publisher
|
| Nguyen T, Kabotyanski E, Reineke L, Shao J, Xiong F, Lee J, et al. The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020;48:2621-2642 pubmed publisher
|
| Stoyas C, Bushart D, Switonski P, Ward J, Alaghatta A, Tang M, et al. Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. Neuron. 2019;: pubmed publisher
|
| Michelena J, Gatti M, Teloni F, Imhof R, Altmeyer M. Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions. J Cell Biol. 2019;218:2865-2875 pubmed publisher
|
| Garg J, Saettone A, Nabeel Shah S, Cadorin M, Ponce M, Marquez S, et al. The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Curr Biol. 2019;29:2371-2379.e6 pubmed publisher
|
| Qin Y, Sekine I, Hanazono M, Morinaga T, Fan M, Takiguchi Y, et al. AMPK activation induced in pemetrexed-treated cells is associated with development of drug resistance independently of target enzyme expression. Mol Oncol. 2019;13:1419-1432 pubmed publisher
|
| Kohutova A, Raška J, Krutá M, Šeneklová M, Bárta T, Fojtik P, et al. Ligase 3-mediated end-joining maintains genome stability of human embryonic stem cells. FASEB J. 2019;33:6778-6788 pubmed publisher
|
| Zhong B, Shingyoji M, Hanazono M, Nguyễn T, Morinaga T, Tada Y, et al. A p53-stabilizing agent, CP-31398, induces p21 expression with increased G2/M phase through the YY1 transcription factor in esophageal carcinoma defective of the p53 pathway. Am J Cancer Res. 2019;9:79-93 pubmed
|
| Wang Z, Song Y, Li S, Kurian S, Xiang R, Chiba T, et al. DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse. J Biol Chem. 2019;294:3909-3919 pubmed publisher
|
| Teloni F, Michelena J, Lezaja A, Kiliç S, Ambrosi C, Menon S, et al. Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability. Mol Cell. 2019;73:670-683.e12 pubmed publisher
|
| Saxena S, Somyajit K, Nagaraju G. XRCC2 Regulates Replication Fork Progression during dNTP Alterations. Cell Rep. 2018;25:3273-3282.e6 pubmed publisher
|
| Maffucci P, Chavez J, Jurkiw T, O Brien P, Abbott J, Reynolds P, et al. Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies. J Clin Invest. 2018;128:5489-5504 pubmed publisher
|
| Przetocka S, Porro A, Bolck H, Walker C, Lezaja A, Trenner A, et al. CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress. Mol Cell. 2018;72:568-582.e6 pubmed publisher
|
| Hjorth Jensen K, Maya Mendoza A, Dalgaard N, Sigurðsson J, Bartek J, Iglesias Gato D, et al. SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability. Nucleic Acids Res. 2018;46:9484-9495 pubmed publisher
|
| Michelena J, Lezaja A, Teloni F, Schmid T, Imhof R, Altmeyer M. Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance. Nat Commun. 2018;9:2678 pubmed publisher
|
| Friedman J, Morisada M, Sun L, Moore E, Padget M, Hodge J, et al. Inhibition of WEE1 kinase and cell cycle checkpoint activation sensitizes head and neck cancers to natural killer cell therapies. J Immunother Cancer. 2018;6:59 pubmed publisher
|
| Sang M, Nakamura M, Ogata T, Sun D, Shimozato O, Nikaido T, et al. Impact of RUNX2 gene silencing on the gemcitabine sensitivity of p53?mutated pancreatic cancer MiaPaCa?2 spheres. Oncol Rep. 2018;39:2749-2758 pubmed publisher
|
| Perucca P, Mocchi R, Guardamagna I, Bassi E, Sommatis S, Nardo T, et al. A damaged DNA binding protein 2 mutation disrupting interaction with proliferating-cell nuclear antigen affects DNA repair and confers proliferation advantage. Biochim Biophys Acta Mol Cell Res. 2018;1865:898-907 pubmed publisher
|
| Kwasna D, Abdul Rehman S, Natarajan J, Matthews S, Madden R, De Cesare V, et al. Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Mol Cell. 2018;70:150-164.e6 pubmed publisher
|
| Massonneau J, Ouellet C, Lucien F, Dubois C, Tyler J, Boissonneault G. Suboptimal extracellular pH values alter DNA damage response to induced double-strand breaks. FEBS Open Bio. 2018;8:416-425 pubmed publisher
|
| Mlcochova P, Caswell S, Taylor I, Towers G, Gupta R. DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages. EMBO J. 2018;37:50-62 pubmed publisher
|
| Taglialatela A, Alvarez S, Leuzzi G, Sannino V, Ranjha L, Huang J, et al. Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers. Mol Cell. 2017;68:414-430.e8 pubmed publisher
|
| Paculova H, Kramara J, Simečková S, Fedr R, Soucek K, Hylse O, et al. BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors. Tumour Biol. 2017;39:1010428317727479 pubmed publisher
|
| Valianatos G, Valcikova B, Growkova K, Verlande A, Mlcochova J, Radova L, et al. A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein. PLoS ONE. 2017;12:e0185801 pubmed publisher
|
| Yamauchi S, Zhong B, Kawamura K, Yang S, Kubo S, Shingyoji M, et al. Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes. BMC Cancer. 2017;17:622 pubmed publisher
|
| Ogata T, Nakamura M, Sang M, Yoda H, Hiraoka K, Yin D, et al. Depletion of runt-related transcription factor 2 (RUNX2) enhances SAHA sensitivity of p53-mutated pancreatic cancer cells through the regulation of mutant p53 and TAp63. PLoS ONE. 2017;12:e0179884 pubmed publisher
|
| Akematsu T, Fukuda Y, Garg J, Fillingham J, Pearlman R, Loidl J. Post-meiotic DNA double-strand breaks occur in Tetrahymena, and require Topoisomerase II and Spo11. elife. 2017;6: pubmed publisher
|
| Pellegrino S, Michelena J, Teloni F, Imhof R, Altmeyer M. Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin. Cell Rep. 2017;19:1819-1831 pubmed publisher
|
| Yamauchi M, Shibata A, Suzuki K, Suzuki M, Niimi A, Kondo H, et al. Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1. Sci Rep. 2017;7:41812 pubmed publisher
|
| Feng W, Hale C, Over R, Cokus S, Jacobsen S, Michaels S. Large-scale heterochromatin remodeling linked to overreplication-associated DNA damage. Proc Natl Acad Sci U S A. 2017;114:406-411 pubmed publisher
|
| S Pedersen R, Karemore G, Gudjonsson T, Rask M, Neumann B, Hériché J, et al. Profiling DNA damage response following mitotic perturbations. Nat Commun. 2016;7:13887 pubmed publisher
|
| Nyeste A, Bencsura P, Vida I, Hegyi Z, Homolya L, Fodor E, et al. Expression of the Prion Protein Family Member Shadoo Causes Drug Hypersensitivity That Is Diminished by the Coexpression of the Wild Type Prion Protein. J Biol Chem. 2016;291:4473-86 pubmed publisher
|
| Udugama M, M Chang F, Chan F, Tang M, Pickett H, R McGhie J, et al. Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres. Nucleic Acids Res. 2015;43:10227-37 pubmed publisher
|
| Sandoval P, Lee P, Meng X, Kapler G. Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. PLoS Genet. 2015;11:e1005405 pubmed publisher
|
| Horrell S, Chalker D. LIA4 encodes a chromoshadow domain protein required for genomewide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell. 2014;13:1300-11 pubmed publisher
|
| Zhdanova N, Draskovic I, Minina J, Karamysheva T, Novo C, Liu W, et al. Recombinogenic telomeres in diploid Sorex granarius (Soricidae, Eulipotyphla) fibroblast cells. Mol Cell Biol. 2014;34:2786-99 pubmed publisher
|
| Crown K, Savytskyy O, Malik S, LOGSDON J, Williams R, Tainer J, et al. A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independent meiotic recombination and chromosome segregation. G3 (Bethesda). 2013;3:1927-43 pubmed publisher
|
| Jha H, Upadhyay S, A J Prasad M, Lu J, Cai Q, Saha A, et al. H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence. J Virol. 2013;87:5255-69 pubmed publisher
|
| Titus S, Li F, Stobezki R, Akula K, Unsal E, Jeong K, et al. Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans. Sci Transl Med. 2013;5:172ra21 pubmed publisher
|
| Kuefner M, Brand M, Ehrlich J, Braga L, Uder M, Semelka R. Effect of antioxidants on X-ray-induced ?-H2AX foci in human blood lymphocytes: preliminary observations. Radiology. 2012;264:59-67 pubmed publisher
|
| Yoshihara Y, Wu D, Kubo N, Sang M, Nakagawara A, Ozaki T. Inhibitory role of E2F-1 in the regulation of tumor suppressor p53 during DNA damage response. Biochem Biophys Res Commun. 2012;421:57-63 pubmed publisher
|
| Kaul Z, Cesare A, Huschtscha L, Neumann A, Reddel R. Five dysfunctional telomeres predict onset of senescence in human cells. EMBO Rep. 2011;13:52-9 pubmed publisher
|
| Martinelli P, Bonetti P, Sironi C, Pruneri G, Fumagalli C, Raviele P, et al. The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway. Blood. 2011;117:6617-26 pubmed publisher
|
| Li M, Xu X, Liu Y. The SET2-RPB1 interaction domain of human RECQ5 is important for transcription-associated genome stability. Mol Cell Biol. 2011;31:2090-9 pubmed publisher
|
| Lee J, Hirano T. RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis. J Cell Biol. 2011;192:263-76 pubmed publisher
|
| Widodo N, Priyandoko D, Shah N, Wadhwa R, Kaul S. Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling. PLoS ONE. 2010;5:e13536 pubmed publisher
|
| Suzuki K, Yamauchi M, Oka Y, Suzuki M, Yamashita S. A novel and simple micro-irradiation technique for creating localized DNA double-strand breaks. Nucleic Acids Res. 2010;38:e129 pubmed publisher
|
| Massignan T, Stewart R, Biasini E, Solomon I, Bonetto V, Chiesa R, et al. A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein. J Biol Chem. 2010;285:7752-65 pubmed publisher
|
| Loidl J, Mochizuki K. Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage. Mol Biol Cell. 2009;20:2428-37 pubmed publisher
|
| Akbay E, Contreras C, Perera S, Sullivan J, Broaddus R, Schorge J, et al. Differential roles of telomere attrition in type I and II endometrial carcinogenesis. Am J Pathol. 2008;173:536-44 pubmed publisher
|
| Mochizuki K, Novatchkova M, Loidl J. DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena. J Cell Sci. 2008;121:2148-58 pubmed publisher
|
| Xiao R, Sun Y, Ding J, Lin S, Rose D, Rosenfeld M, et al. Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol. 2007;27:5393-402 pubmed
|