product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
protein
product name :
Recombinant Mouse IL-2 (carrier-free)
catalog :
575404
quantity :
25 μg
price :
211 USD
more info or order :
citations: 24
Reference
Montes De Oca M, de Labastida Rivera F, Winterford C, Frame T, Ng S, Amante F, et al. IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection. PLoS Pathog. 2020;16:e1008994 pubmed publisher
Frech M, Knipfer L, Wirtz S, Zaiss M. An in vivo gene delivery approach for the isolation of reasonable numbers of type 2 innate lymphoid cells. MethodsX. 2020;7:101054 pubmed publisher
Walter F, Winter E, Rahn S, Heidland J, Meier S, Struzek A, et al. Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses. PLoS ONE. 2020;15:e0239369 pubmed publisher
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
Loo C, Gatchalian J, Liang Y, Leblanc M, Xie M, Ho J, et al. A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function. Immunity. 2020;53:143-157.e8 pubmed publisher
Mohammadpour H, Sarow J, MacDonald C, Chen G, Qiu J, Sharma U, et al. β2-Adrenergic receptor activation on donor cells ameliorates acute GvHD. JCI Insight. 2020;5: pubmed publisher
Han S, Chung D, St Paul M, Liu Z, Garcia Batres C, Elford A, et al. Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells. Oncoimmunology. 2020;9:1737368 pubmed publisher
Takushi S, Paik N, Fedanov A, Prince C, Doering C, Spencer H, et al. Lentiviral Gene Therapy for Familial Hemophagocytic Lymphohistiocytosis Type 3, Caused by UNC13D Genetic Defects. Hum Gene Ther. 2020;31:626-638 pubmed publisher
Ruscetti M, Morris J, Mezzadra R, Russell J, Leibold J, Romesser P, et al. Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Cell. 2020;181:424-441.e21 pubmed publisher
Muthalagu N, Monteverde T, Raffo Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, et al. Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2020;10:872-887 pubmed publisher
Choi H, Won T, Hou X, Chen G, Bracamonte Baran W, Talor M, et al. Innate Lymphoid Cells Play a Pathogenic Role in Pericarditis. Cell Rep. 2020;30:2989-3003.e6 pubmed publisher
Hurrell B, Galle Treger L, Jahani P, Howard E, Helou D, Banie H, et al. TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity. Cell Rep. 2019;29:4509-4524.e5 pubmed publisher
Gomez Lopez N, Romero R, Xu Y, Miller D, Arenas Hernandez M, Garcia Flores V, et al. Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth. J Immunol. 2019;203:1793-1807 pubmed publisher
Walker J, Clark P, Crisp A, Barlow J, Szeto A, Ferreira A, et al. Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow. Immunity. 2019;: pubmed publisher
Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, et al. Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. Sci Rep. 2019;9:6136 pubmed publisher
Liu B, Salgado O, Singh S, Hippen K, Maynard J, Burlingame A, et al. The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation. Nat Commun. 2019;10:354 pubmed publisher
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, et al. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nat Med. 2018;24:1550-1558 pubmed publisher
Sultan H, Kumai T, Fesenkova V, Fan A, Wu J, Cho H, et al. Sustained Persistence of IL2 Signaling Enhances the Antitumor Effect of Peptide Vaccines through T-cell Expansion and Preventing PD-1 Inhibition. Cancer Immunol Res. 2018;6:617-627 pubmed publisher
Palazon A, Tyrakis P, Macías D, Veliça P, Rundqvist H, Fitzpatrick S, et al. An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression. Cancer Cell. 2017;32:669-683.e5 pubmed publisher
Bao K, Carr T, Wu J, Barclay W, Jin J, Ciofani M, et al. BATF Modulates the Th2 Locus Control Region and Regulates CD4+ T Cell Fate during Antihelminth Immunity. J Immunol. 2016;197:4371-4381 pubmed
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schluter D, et al. Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice. PLoS ONE. 2016;11:e0162863 pubmed publisher
Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, et al. DCAF1 controls T-cell function via p53-dependent and -independent mechanisms. Nat Commun. 2016;7:10307 pubmed publisher
Jacque E, Schweighoffer E, Tybulewicz V, Ley S. BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival. J Exp Med. 2015;212:883-92 pubmed publisher
Detanico T, Heiser R, Aviszus K, Bonorino C, Wysocki L. Self-tolerance checkpoints in CD4 T cells specific for a peptide derived from the B cell antigen receptor. J Immunol. 2011;187:82-91 pubmed publisher
product information
Antigen :
IL-2
Apps. Abbrev. :
BA
Cat # :
575404
Item :
Recombinant Mouse IL-2 (carrier-free)
Other Names :
Interleukin-2, T cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF)
Size :
25 μg
Price (USD) :
211 USD
Reactivity :
Mouse
Host :
E. coli
Conjugate/Tag/Label :
RECOM
Application Notes :
BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal or better stability and shelf-life compared to commercially available lyophilized proteins after reconstitution. Our liquid proteins are verified in-house to maintain activity after shipping on blue ice and are backed by our 100% satisfaction guarantee. If you have any concerns, contact us at tech@biolegend.com.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA