product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
protein
product name :
Recombinant Human IL-12 (p70) (carrier-free)
catalog :
573002
quantity :
10 μg
price :
229 USD
more info or order :
citations: 11
Reference
Sparks R, Lau W, Liu C, Han K, Vrindten K, Sun G, et al. Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19. Nature. 2023;614:752-761 pubmed publisher
Smith K, Minns D, McHugh B, Holloway R, O CONNOR R, Williams A, et al. The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation. PLoS Biol. 2022;20:e3001554 pubmed publisher
Zhou Y, Li X, Shen R, Wang X, Zhang F, Liu S, et al. Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways. Front Immunol. 2022;13:884399 pubmed publisher
Baleeiro R, Bouwens C, Liu P, DI Gioia C, Dunmall L, Nagano A, et al. MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy. Oncoimmunology. 2022;11:2080329 pubmed publisher
McTernan P, Levitt D, Welsh D, Simon L, Siggins R, Molina P. Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells. Front Immunol. 2022;13:839390 pubmed publisher
Rafieerad A, Yan W, Alagarsamy K, Srivastava A, Sareen N, Arora R, et al. Fabrication of Smart Tantalum Carbide MXene Quantum Dots with Intrinsic Immunomodulatory Properties for Treatment of Allograft Vasculopathy. Adv Funct Mater. 2021;31:2106786 pubmed publisher
Wilmes S, Jeffrey P, Martínez Fábregas J, Hafer M, Fyfe P, Pohler E, et al. Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses. elife. 2021;10: pubmed publisher
Martínez Fábregas J, Wang L, Pohler E, Cozzani A, Wilmes S, Kazemian M, et al. CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci. Cell Rep. 2020;33:108545 pubmed publisher
Liu Y, Lightfoot Y, Seto N, Carmona Rivera C, Moore E, Goel R, et al. Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus. JCI Insight. 2018;3: pubmed publisher
Foltz J, Moseman J, Thakkar A, Chakravarti N, Lee D. TGFβ Imprinting During Activation Promotes Natural Killer Cell Cytokine Hypersecretion. Cancers (Basel). 2018;10: pubmed publisher
Geiger R, Rieckmann J, Wolf T, Basso C, Feng Y, Fuhrer T, et al. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity. Cell. 2016;167:829-842.e13 pubmed publisher
product information
Antigen :
IL-12 p70
Apps. Abbrev. :
BA
Cat # :
573002
Item :
Recombinant Human IL-12 (p70) (carrier-free)
Other Names :
Natural killer cell stimulatory factor (NKSF), cytotoxic lymphocyte maturation factor (CLMF)
Size :
10 μg
Price (USD) :
229 USD
Reactivity :
Human
Host :
ADD EXPRESSION SYSTEM HERE
Conjugate/Tag/Label :
RECOM
Application Notes :
BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal or better stability and shelf-life compared to commercially available lyophilized proteins after reconstitution. Our liquid proteins are verified in-house to maintain activity after shipping on blue ice and are backed by our 100% satisfaction guarantee. If you have any concerns, contact us at tech@biolegend.com.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA