product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
protein
product name :
Recombinant Human IL-6 (carrier-free)
catalog :
570804
quantity :
25 μg
price :
253 USD
more info or order :
citations: 21
Reference
Woodley K, Dillingh L, Giotopoulos G, Madrigal P, Rattigan K, Philippe C, et al. Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nat Commun. 2023;14:2132 pubmed publisher
Park S, Seo Y, Kim L, Kim H, Yoon K, Heo T. Butein Inhibits Cell Growth by Blocking the IL-6/IL-6Rα Interaction in Human Ovarian Cancer and by Regulation of the IL-6/STAT3/FoxO3a Pathway. Int J Mol Sci. 2023;24: pubmed publisher
Devi S, Indramohan M, J xe4 ger E, Carrière J, Chu L, de Almeida L, et al. CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout. Cell Rep. 2023;42:112265 pubmed publisher
Yamaguchi Y, Gibson J, Ou K, Lopez L, Ng R, Leggett N, et al. PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages. J Immunother Cancer. 2022;10: pubmed publisher
Baleeiro R, Bouwens C, Liu P, DI Gioia C, Dunmall L, Nagano A, et al. MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy. Oncoimmunology. 2022;11:2080329 pubmed publisher
Guo Q, Malloy M, Roweth H, McAllister S, Italiano J, Battinelli E. Platelets upregulate tumor cell programmed death ligand 1 in an epidermal growth factor receptor-dependent manner in vitro. Blood Adv. 2022;6:5668-5675 pubmed publisher
Miyamoto T, Murakami R, Hamanishi J, Tanigaki K, Hosoe Y, Mise N, et al. B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression. Cancer Immunol Res. 2022;10:56-69 pubmed publisher
Khanam A, Tang L, Kottilil S. Programmed death 1 expressing CD8+ CXCR5+ follicular T cells constitute effector rather than exhaustive phenotype in patients with chronic hepatitis B. Hepatology. 2022;75:690-708 pubmed publisher
Ianniciello A, Zarou M, Rattigan K, Scott M, Dawson A, Dunn K, et al. ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy. Sci Transl Med. 2021;13:eabd5016 pubmed publisher
Kaiser R, Leunig A, Pekayvaz K, Popp O, Joppich M, Polewka V, et al. Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. JCI Insight. 2021;6: pubmed publisher
Gopinath A, Badov M, Francis M, Shaw G, Collins A, Miller D, et al. TNFα increases tyrosine hydroxylase expression in human monocytes. NPJ Parkinsons Dis. 2021;7:62 pubmed publisher
Yang F, He Z, Duan H, Zhang D, Li J, Yang H, et al. Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40. Nat Commun. 2021;12:3424 pubmed publisher
Minns D, Smith K, Alessandrini V, Hardisty G, Melrose L, Jackson Jones L, et al. The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation. Nat Commun. 2021;12:1285 pubmed publisher
Zhang H, Wang Y, Wang Q, Sun S, Li S, Shang H, et al. Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12. Front Cell Dev Biol. 2020;8:205 pubmed publisher
Sugawara E, Kato M, Kudo Y, Lee W, Hisada R, Fujieda Y, et al. Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts. Autophagy. 2020;16:946-955 pubmed publisher
Wong G, Barmettler S, Heather J, Millar D, Penny S, Huissoon A, et al. Aberrant X chromosome skewing and acquired clonal hematopoiesis in adult-onset common variable immunodeficiency. JCI Insight. 2019;4: pubmed publisher
Guo J, Muse E, Christians A, Swanson S, Davila E. An Anticancer Drug Cocktail of Three Kinase Inhibitors Improved Response to a Dendritic Cell-Based Cancer Vaccine. Cancer Immunol Res. 2019;7:1523-1534 pubmed publisher
Fulciniti M, Lin C, Samur M, Lopez M, Singh I, Lawlor M, et al. Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma. Cell Rep. 2018;25:3693-3705.e6 pubmed publisher
Ibrahim M, Klement J, Lu C, Redd P, Xiao W, Yang D, et al. Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis. Cell Rep. 2018;25:3036-3046.e6 pubmed publisher
Jokela T, Engelsen A, Rybicka A, Pelissier Vatter F, Garbe J, Miyano M, et al. Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance. Front Cell Dev Biol. 2018;6:41 pubmed publisher
Reitsma J, Sato H, Nevels M, Terhune S, Paulus C. Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus. J Virol. 2013;87:10763-76 pubmed publisher
product information
Antigen :
IL-6
Apps. Abbrev. :
BA
Cat # :
570804
Item :
Recombinant Human IL-6 (carrier-free)
Other Names :
Interleukin-6, B cell stimulating factor-2 (BSF-2), Cytotoxic T cell differentiation factor (CDF), Hepatocyte stimulating factor (HSF), Hybridoma/plasmacytoma growth factor (HPGF)
Size :
25 μg
Price (USD) :
253 USD
Reactivity :
Human
Host :
ADD EXPRESSION SYSTEM HERE
Conjugate/Tag/Label :
RECOM
Application Notes :
BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal or better stability and shelf-life compared to commercially available lyophilized proteins after reconstitution. Our liquid proteins are verified in-house to maintain activity after shipping on blue ice and are backed by our 100% satisfaction guarantee. If you have any concerns, contact us at tech@biolegend.com.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA