product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
protein
product name :
Recombinant Human IFN-γ (carrier-free)
catalog :
570206
quantity :
100 μg
price :
229 USD
more info or order :
citations: 32
Reference
Arnold K, Peterson L, Beck L, Brewer M. JAK Signaling Is Critically Important in Cytokine-Induced Viral Susceptibility of Keratinocytes. Int J Mol Sci. 2023;24: pubmed publisher
Mavrikaki M, Lee J, Solomon I, Slack F. Severe COVID-19 is associated with molecular signatures of aging in the human brain. Nat Aging. 2022;2:1130-1137 pubmed publisher
Tsai M, Osman W, Adair J, ElMergawy R, Chafin L, Johns F, et al. The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection. J Biol Chem. 2022;298:102698 pubmed publisher
Hogg S, Motorna O, Kearney C, Derrick E, House I, Todorovski I, et al. Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer. Clin Epigenetics. 2022;14:96 pubmed publisher
Yamaguchi Y, Gibson J, Ou K, Lopez L, Ng R, Leggett N, et al. PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages. J Immunother Cancer. 2022;10: pubmed publisher
Baleeiro R, Bouwens C, Liu P, DI Gioia C, Dunmall L, Nagano A, et al. MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy. Oncoimmunology. 2022;11:2080329 pubmed publisher
Taniguchi H, Caeser R, Chavan S, Zhan Y, Chow A, Manoj P, et al. WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep. 2022;39:110814 pubmed publisher
Guo Q, Malloy M, Roweth H, McAllister S, Italiano J, Battinelli E. Platelets upregulate tumor cell programmed death ligand 1 in an epidermal growth factor receptor-dependent manner in vitro. Blood Adv. 2022;6:5668-5675 pubmed publisher
Shikama Y, Kurosawa M, Furukawa M, Kudo Y, Ishimaru N, Matsushita K. The Priming Potential of Interferon Lambda-1 for Antiviral Defense in the Oral Mucosa. Inflammation. 2022;: pubmed publisher
Miyamoto T, Murakami R, Hamanishi J, Tanigaki K, Hosoe Y, Mise N, et al. B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression. Cancer Immunol Res. 2022;10:56-69 pubmed publisher
Zhang Z, Yang A, Chaurasiya S, Park A, Lu J, Kim S, et al. CF33-hNIS-antiPDL1 virus primes pancreatic ductal adenocarcinoma for enhanced anti-PD-L1 therapy. Cancer Gene Ther. 2022;29:722-733 pubmed publisher
Rafieerad A, Yan W, Alagarsamy K, Srivastava A, Sareen N, Arora R, et al. Fabrication of Smart Tantalum Carbide MXene Quantum Dots with Intrinsic Immunomodulatory Properties for Treatment of Allograft Vasculopathy. Adv Funct Mater. 2021;31:2106786 pubmed publisher
Chen B, Scurrah C, McKinley E, Simmons A, Ramirez Solano M, Zhu X, et al. Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps. Cell. 2021;184:6262-6280.e26 pubmed publisher
Zhang C, Chinnappan M, Prestwood C, Edwards M, Artami M, Thompson B, et al. Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Jiang Z, Lim S, Yan M, Hsu J, Yao J, Wei Y, et al. TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis. J Clin Invest. 2021;131: pubmed publisher
Sharma V, Pope B, Santiago N, Boland M, Sun D, Reynolds R, et al. Decreased Levels of STAT1 and Interferon-γ-Induced STAT1 Phosphorylation in Rheumatoid Arthritis CD4 and CD8 T Cells. ACR Open Rheumatol. 2021;3:277-283 pubmed publisher
Stringhini M, Mock J, Fontana V, Murer P, Neri D. Antibody-mediated delivery of LIGHT to the tumor boosts natural killer cells and delays tumor progression. MAbs. 2021;13:1868066 pubmed publisher
Becker W, Alrafas H, Busbee P, Walla M, Wilson K, Miranda K, et al. Cannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis. J Crohns Colitis. 2021;15:1032-1048 pubmed publisher
Stebbing J, Sánchez Nievas G, Falcone M, Youhanna S, Richardson P, Ottaviani S, et al. JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality. Sci Adv. 2021;7: pubmed publisher
Wrenn E, Yamamoto A, Moore B, Huang Y, McBirney M, Thomas A, et al. Regulation of Collective Metastasis by Nanolumenal Signaling. Cell. 2020;183:395-410.e19 pubmed publisher
Lin H, Ji D, Lucherelli M, Reina G, Ippolito S, Samor xec P, et al. Comparative Effects of Graphene and Molybdenum Disulfide on Human Macrophage Toxicity. Small. 2020;16:e2002194 pubmed publisher
Nenasheva T, Gerasimova T, Serdyuk Y, Grigor eva E, Kosmiadi G, Nikolaev A, et al. Macrophages Derived From Human Induced Pluripotent Stem Cells Are Low-Activated "Naïve-Like" Cells Capable of Restricting Mycobacteria Growth. Front Immunol. 2020;11:1016 pubmed publisher
Brasil da Costa F, Lewis M, Truong A, Carson D, Farach Carson M. SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models. PLoS ONE. 2020;15:e0230354 pubmed publisher
Zhang H, Wang Y, Wang Q, Sun S, Li S, Shang H, et al. Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12. Front Cell Dev Biol. 2020;8:205 pubmed publisher
Gruber C, Martín Fernandez M, Ailal F, Qiu X, Taft J, Altman J, et al. Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy. J Exp Med. 2020;217: pubmed publisher
Rajan S, Amin A, Li L, Rolland D, Li H, Kwon D, et al. The mechanism of cancer drug addiction in ALK-positive T-Cell lymphoma. Oncogene. 2020;39:2103-2117 pubmed publisher
Gilad Y, Eliaz Y, Yu Y, Han S, O Malley B, Lonard D. Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination. Sci Rep. 2019;9:15099 pubmed publisher
Nguyen D, Theodoropoulos G, Li Y, Wu C, Sha W, Feun L, et al. Targeting the Kynurenine Pathway for the Treatment of Cisplatin-Resistant Lung Cancer. Mol Cancer Res. 2020;18:105-117 pubmed publisher
Sugawara E, Kato M, Kudo Y, Lee W, Hisada R, Fujieda Y, et al. Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts. Autophagy. 2020;16:946-955 pubmed publisher
Guo J, Muse E, Christians A, Swanson S, Davila E. An Anticancer Drug Cocktail of Three Kinase Inhibitors Improved Response to a Dendritic Cell-Based Cancer Vaccine. Cancer Immunol Res. 2019;7:1523-1534 pubmed publisher
Jenks S, Cashman K, Zumaquero E, Marigorta U, Patel A, Wang X, et al. Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus. Immunity. 2018;49:725-739.e6 pubmed publisher
Tran L, Allen C, Xiao R, Moore E, Davis R, Park S, et al. Cisplatin Alters Antitumor Immunity and Synergizes with PD-1/PD-L1 Inhibition in Head and Neck Squamous Cell Carcinoma. Cancer Immunol Res. 2017;5:1141-1151 pubmed publisher
product information
Antigen :
IFN-gamma
Apps. Abbrev. :
BA
Cat # :
570206
Item :
Recombinant Human IFN-γ (carrier-free)
Other Names :
Interferon-γ, Immune interferon, Type II interferon, T cell interferon, Macrophage-activating factor (MAF),
Size :
100 μg
Price (USD) :
229 USD
Reactivity :
Human
Host :
ADD EXPRESSION SYSTEM HERE
Conjugate/Tag/Label :
RECOM
Application Notes :
BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal or better stability and shelf-life compared to commercially available lyophilized proteins after reconstitution. Our liquid proteins are verified in-house to maintain activity after shipping on blue ice and are backed by our 100% satisfaction guarantee. If you have any concerns, contact us at tech@biolegend.com.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA