Ultra-LEAF™ Purified anti-human/mouse TGF-β1 | BioLegend 521708 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human/mouse TGF-β1

catalog :

521708

quantity :

1 mg

price :

743 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

19D8

reactivity :

human, mouse

application :

neutralization

more info or order :

BioLegend product webpage

citations: 7

Reference
Shen Y, Lu C, Song Z, Qiao C, Wang J, Chen J, et al. Ursodeoxycholic acid reduces antitumor immunosuppression by inducing CHIP-mediated TGF-β degradation. Nat Commun. 2022;13:3419 pubmed publisher
Rivera C, Randrian V, Richer W, Gerber Ferder Y, Delgado M, Chikina A, et al. Epithelial colonization by gut dendritic cells promotes their functional diversification. Immunity. 2022;55:129-144.e8 pubmed publisher
Weinstock A, RAHMAN K, Yaacov O, Nishi H, Menon P, Nikain C, et al. Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. elife. 2021;10: pubmed publisher
Yoon H, Tang C, Banerjee S, Delgado A, Yebra M, Davis J, et al. TGF-β1-mediated transition of resident fibroblasts to cancer-associated fibroblasts promotes cancer metastasis in gastrointestinal stromal tumor. Oncogenesis. 2021;10:13 pubmed publisher
Li L, Wei J, Dong J, Lin Q, Tang H, Jia Y, et al. Laminin γ2-mediating T cell exclusion attenuates response to anti-PD-1 therapy. Sci Adv. 2021;7: pubmed publisher
Nakayama K, Onishi H, Fujimura A, Imaizumi A, Kawamoto M, Oyama Y, et al. NFκB and TGFβ contribute to the expression of PTPN3 in activated human lymphocytes. Cell Immunol. 2020;358:104237 pubmed publisher
Mansouri S, Katikaneni D, Gogoi H, Pipkin M, Machuca T, Emtiazjoo A, et al. Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state. Mucosal Immunol. 2020;13:595-608 pubmed publisher

product information

Antigen :

TGF-beta1

Apps. Abbrev. :

Block

Cat # :

521708

Clone :

19D8

Item :

Ultra-LEAF™ Purified anti-human/mouse TGF-β1

Isotype :

Mouse IgG1, κ

Other Names :

Transforming growth factor-beta 1 (TGF-b1), TGFB1, CED, DPD1

Size :

1 mg

Price (USD) :

743 USD

Reactivity :

Human, Mouse

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

Human TGF-β1

Application Notes :

ELISA Detection: To measure TGF-ß1, this antibody can be used as a detection antibody in sandwich ELISA format, and paired with the purified 21C11 antibody (Cat. No. 525301) as the capture antibody. Recombinant Human TGF-ß1 (ELISA Std.) (Cat. No. 580709) can be used as the protein standard.Blocking: Clone 19D8 LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is useful for in vitro blocking of human and mouse TGF-ß1 bioactivity. The 19D8 clone does not inhibit the bioactivity of human TGF-ß2 or TGF-ß3 in the Mv1Lu-(caga)12-Luc reporter cell assay.Note: For testing TGF-ß1 in serum, plasma or supernatant, BioLegend's ELISA LEGEND MAX™ Kits (Cat. No. 436708 & 437708) are specially developed and recommended.;

more info or order :

BioLegend product webpage