product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse IL-9
catalog :
514103
quantity :
25 μg
price :
183 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
RM9A4
reactivity :
mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 1
Zhao Y, Chu X, Chen J, Wang Y, Gao S, Jiang Y, et al. Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells. Nat Commun. 2016;7:12368 pubmed publisher
Roy S, Rizvi Z, Clarke A, MacDonald F, Pandey A, Zaiss D, et al. EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells. Nat Commun. 2021;12:3182 pubmed publisher
Chen J, Ding Y, Huang F, Lan R, Wang Z, Huang W, et al. Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells. Oncol Lett. 2021;21:409 pubmed publisher
Alhosaini K, Ansari M, Nadeem A, Bakheet S, Attia S, Alhazzani K, et al. 5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism. Brain Sci. 2021;11: pubmed publisher
Dong M, Wang G, Chow R, Ye L, Zhu L, Dai X, et al. Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells. Cell. 2019;178:1189-1204.e23 pubmed publisher
Jiang Y, Chen J, Bi E, Zhao Y, Qin T, Wang Y, et al. TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways. J Immunother Cancer. 2019;7:28 pubmed publisher
Schwartz D, Farley T, Richoz N, Yao C, Shih H, Petermann F, et al. Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology. Immunity. 2019;50:106-120.e10 pubmed publisher
Schaper Gerhardt K, Wohlert M, Mommert S, Kietzmann M, Werfel T, Gutzmer R. Stimulation of histamine H4 receptors increases the production of IL-9 in Th9 polarized cells. Br J Pharmacol. 2020;177:614-622 pubmed publisher
Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed publisher
Gomez Rodriguez J, Meylan F, Handon R, Hayes E, Anderson S, Kirby M, et al. Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4. Nat Commun. 2016;7:10857 pubmed publisher
Prins J, Zhang B, Schjenken J, Guerin L, Barry S, Robertson S. Unstable Foxp3+ regulatory T cells and altered dendritic cells are associated with lipopolysaccharide-induced fetal loss in pregnant interleukin 10-deficient mice. Biol Reprod. 2015;93:95 pubmed publisher
Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, et al. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014;5:3555 pubmed publisher
Mikami N, Miyagi Y, Sueda K, Takatsuji M, Fukada S, Yamamoto H, et al. Calcitonin gene-related peptide and cyclic adenosine 5'-monophosphate/protein kinase A pathway promote IL-9 production in Th9 differentiation process. J Immunol. 2013;190:4046-55 pubmed publisher
Reynolds L, Maizels R. Cutting edge: in the absence of TGF-? signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-? production renders mice more susceptible to helminth infection. J Immunol. 2012;189:1113-7 pubmed publisher
Takami M, Love R, Iwashima M. TGF-? converts apoptotic stimuli into the signal for Th9 differentiation. J Immunol. 2012;188:4369-75 pubmed publisher
Zhou Y, Sonobe Y, Akahori T, Jin S, Kawanokuchi J, Noda M, et al. IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes. J Immunol. 2011;186:4415-21 pubmed publisher
Tan C, Aziz M, Lovaas J, Vistica B, Shi G, Wawrousek E, et al. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J Immunol. 2010;185:6795-801 pubmed publisher
Chang H, Sehra S, Goswami R, Yao W, Yu Q, Stritesky G, et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol. 2010;11:527-34 pubmed publisher
Kim B, Kim I, Park Y, Kim Y, Kim Y, Chang W, et al. Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma. Proc Natl Acad Sci U S A. 2010;107:8742-7 pubmed publisher
Angkasekwinai P, Chang S, Thapa M, Watarai H, Dong C. Regulation of IL-9 expression by IL-25 signaling. Nat Immunol. 2010;11:250-6 pubmed publisher
product information
Antigen :
IL-9
Apps. Abbrev. :
ICFC
Cat # :
514103
Clone :
RM9A4
Item :
PE anti-mouse IL-9
Isotype :
Rat IgG1, κ
Other Names :
Interleukin-9, P40, Mast cell growth factor (MCGF), Megakaryoblast growth factor, T cell growth factor-3 (TCGF-3)
Size :
25 μg
Price (USD) :
183 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
Recombinant full length mouse IL-9
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA