LEAF™ Purified anti-mouse VEGF-A | BioLegend 512808 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-mouse VEGF-A

catalog :

512808

quantity :

500 μg

price :

450 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

2G11-2A05

reactivity :

mouse

application :

western blot, ELISA, neutralization, immunohistochemistry - frozen section

citations: 10

Reference
Donovan P, Patel J, Dight J, Wong H, Sim S, Murigneux V, et al. Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nat Commun. 2019;10:18 pubmed publisher
Nagao M, Hamilton J, Kc R, Berendsen A, Duan X, Cheong C, et al. Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis. Sci Rep. 2017;7:13027 pubmed publisher
Zhang W, Ding Y, Zhang C, Lu Q, Liu Z, Coughlan K, et al. Deletion of endothelial cell-specific liver kinase B1 increases angiogenesis and tumor growth via vascular endothelial growth factor. Oncogene. 2017;36:4277-4287 pubmed publisher
Bacigaluppi M, Russo G, Peruzzotti Jametti L, Rossi S, Sandrone S, Butti E, et al. Neural Stem Cell Transplantation Induces Stroke Recovery by Upregulating Glutamate Transporter GLT-1 in Astrocytes. J Neurosci. 2016;36:10529-10544 pubmed
Klose R, Krzywinska E, Castells M, Gotthardt D, Putz E, Kantari Mimoun C, et al. Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia. Nat Commun. 2016;7:12528 pubmed publisher
Kather J, Friedrich J, Woik N, Sticht C, Gretz N, Hammes H, et al. Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice. Invest Ophthalmol Vis Sci. 2014;55:4295-303 pubmed publisher
Jayaraman P, Parikh F, López Rivera E, Hailemichael Y, Clark A, Ma G, et al. Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release. J Immunol. 2012;188:5365-76 pubmed publisher
Lu R, Kujawski M, Pan H, Shively J. Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1. Cancer Res. 2012;72:2239-50 pubmed publisher
Kumar V, Scandella E, Danuser R, Onder L, Nitschké M, Fukui Y, et al. Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Blood. 2010;115:4725-33 pubmed publisher
Wuest T, Carr D. VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis. J Exp Med. 2010;207:101-15 pubmed publisher

product information

Antigen :

VEGF-A

Apps. Abbrev. :

Western Blotting, Neut, ELISA, IHC-F, FA

Cat # :

512808

Clone :

2G11-2A05

Item :

LEAF™ Purified anti-mouse VEGF-A

Isotype :

Rat IgG, κ

Other Names :

Vascular endothelial growth factor (VEGF)

Size :

500 μg

Price (USD) :

450 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

LEAF

Immunogen :

N-terminal 24 aa sequence of murine VEGF

Application Notes :

Neutralization: The Ultra-LEAF™ Purified antibody is recommended for neutralization of mouse VEGF-A bioactivity in vivo 2,4 and in vitro 2 . Western Blotting: It is suggested to use 0.5 - 2 µg/ml for WB 2 . Immunohistochemistry: Clone 2G11-2A05 is recommended for IHC on saponin-treated frozen tissue sections at a concentration range of 5-10 µg/ml. ELISA or ELISPOT: The Ultra-LEAF™ Purified 2G11-2A05 antibody is useful in a mouse VEGF-A ELISA or ELISPOT assay. Functional Assay : The Ultra-LEAF™ Purified 2G11-2A05 antibody is useful in a mouse VEGF-A functional assay 2 .