product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human IL-17A
catalog :
512321
quantity :
25 tests
price :
215 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
BL168
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 6a
Wahid R, Fresnay S, Levine M, Sztein M. Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol. 2016;173:87-95 pubmed publisher
  • flow cytometry; human
Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
Imai H, Kawase T, Yoshida S, Mese T, Roh S, Fujita A, et al. Peripheral T cell profiling reveals downregulated exhaustion marker and increased diversity in lymphedema post-lymphatic venous anastomosis. iScience. 2023;26:106822 pubmed publisher
Cao J, Zhan Y, Ji L, Chen P, Cheng L, Li F, et al. Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia. BMC Immunol. 2023;24:6 pubmed publisher
Hackstein C, Costigan D, Drexhage L, Pearson C, Bullers S, Ilott N, et al. A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice. Nat Commun. 2022;13:7472 pubmed publisher
Asashima H, Axisa P, Pham T, Longbrake E, Ruff W, Lele N, et al. Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis. J Clin Invest. 2022;132: pubmed publisher
Hong Y, Chu Z, Kong J, Li Q, Li N, Liu L, et al. IL-17A aggravates asthma-induced intestinal immune injury by promoting neutrophil trafficking. J Leukoc Biol. 2022;112:425-435 pubmed publisher
Anderson A, Wu I, Parrillo A, Wolf M, Maestas D, Graham I, et al. An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial. NPJ Regen Med. 2022;7:6 pubmed publisher
Torres Ruiz J, Pérez Fragoso A, Maravillas Montero J, Llorente L, Mejía Domínguez N, Páez Franco J, et al. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021;12:689966 pubmed publisher
Shen X, Zhang H, Xie H, Chen L, Li S, Zheng J, et al. Reduced CCR6+IL-17A+Treg Cells in Blood and CCR6-Dependent Accumulation of IL-17A+Treg Cells in Lungs of Patients With Allergic Asthma. Front Immunol. 2021;12:710750 pubmed publisher
Barros Martins J, Hammerschmidt S, Cossmann A, Odak I, Stankov M, Morillas Ramos G, et al. Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Nat Med. 2021;27:1525-1529 pubmed publisher
Khuzwayo S, Mthembu M, Meermeier E, Prakadan S, Kazer S, Bassett T, et al. MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection. Front Immunol. 2021;12:631410 pubmed publisher
Li H, Huang C, Zhang Z, Feng Y, Wang Z, Tang X, et al. MEK Inhibitor Augments Antitumor Activity of B7-H3-Redirected Bispecific Antibody. Front Oncol. 2020;10:1527 pubmed publisher
Faust H, Zhang H, Han J, Wolf M, Jeon O, Sadtler K, et al. IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis. J Clin Invest. 2020;130:5493-5507 pubmed publisher
Huang C, Li H, Feng Y, Li X, Zhang Z, Jiang C, et al. Combination therapy with B7H3-redirected bispecific antibody and Sorafenib elicits enhanced synergistic antitumor efficacy. Theranostics. 2020;10:10498-10512 pubmed publisher
Bailur J, McCachren S, Pendleton K, Vasquez J, Lim H, Duffy A, et al. Risk-associated alterations in marrow T cells in pediatric leukemia. JCI Insight. 2020;5: pubmed publisher
Wood M, Wood L, Templeton M, Fisher B, Lippy A, Jones C, et al. Transient Immune Activation in BCG-Vaccinated Infant Rhesus Macaques Is Not Sufficient to Influence Oral Simian Immunodeficiency Virus Infection. J Infect Dis. 2020;222:44-53 pubmed publisher
Nicholas D, Proctor E, Agrawal M, Belkina A, Van Nostrand S, Panneerseelan Bharath L, et al. Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes. Cell Metab. 2019;30:447-461.e5 pubmed publisher
Zuazo M, Arasanz H, Fernández Hinojal G, García Granda M, Gato M, Bocanegra A, et al. Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy. EMBO Mol Med. 2019;: pubmed publisher
Booth J, Goldberg E, Patil S, Greenwald B, Sztein M. Association between S. Typhi-specific memory CD4+ and CD8+ T responses in the terminal ileum mucosa and in peripheral blood elicited by the live oral typhoid vaccine Ty21a in humans. Hum Vaccin Immunother. 2019;15:1409-1420 pubmed publisher
Nowak A, Lock D, Bacher P, Hohnstein T, Vogt K, Gottfreund J, et al. CD137+CD154- Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures. Front Immunol. 2018;9:199 pubmed publisher
Khaitan A, Kilberg M, Kravietz A, Ilmet T, Tastan C, Mwamzuka M, et al. HIV-Infected Children Have Lower Frequencies of CD8+ Mucosal-Associated Invariant T (MAIT) Cells that Correlate with Innate, Th17 and Th22 Cell Subsets. PLoS ONE. 2016;11:e0161786 pubmed publisher
Ohue Y, Kurose K, Mizote Y, Matsumoto H, Nishio Y, Isobe M, et al. Prolongation of overall survival in advanced lung adenocarcinoma patients with the XAGE1 (GAGED2a) antibody. Clin Cancer Res. 2014;20:5052-63 pubmed publisher
product information
Antigen :
IL-17A
Apps. Abbrev. :
ICFC
Cat # :
512321
Clone :
BL168
Item :
Brilliant Violet 421™ anti-human IL-17A
Isotype :
Mouse IgG1, κ
Other Names :
Interleukin IL-17A, IL-17, Cytotoxic T lymphocyte-associated antigen 8 (CTLA-8)
Size :
25 tests
Price (USD) :
215 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
Recombinant full length human IL-17A
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA