This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
LEAF™ Purified anti-mouse CD254 (TRANCE, RANKL)
catalog :
510008
quantity :
500 μg
price :
340 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
IK22/5
reactivity :
mouse
application :
western blot, neutralization, immunoprecipitation, flow cytometry
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 9d
Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, et al. Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation. J Exp Med. 2018;215:481-500 pubmed publisher
Severe N, Karabacak N, Gustafsson K, Baryawno N, Courties G, Kfoury Y, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25:570-583.e7 pubmed publisher
Montero Herradón S, García Ceca J, Zapata A. Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation. Front Immunol. 2018;9:1020 pubmed publisher
product information
Antigen :
CD254
Apps. Abbrev. :
Flow Cytometry, IP, Western Blotting, Block
Cat # :
510008
Clone :
IK22/5
Item :
LEAF™ Purified anti-mouse CD254 (TRANCE, RANKL)
Isotype :
Rat IgG2a, κ
Other Names :
Tumor necrosis factor-related activation-induced cytokine, Receptor activator of NF-κB ligand (RANK L), Osteoprotegerin ligand (OPGL), Osteoclast differentiation factor (ODF), SOFA, TNFSF-11, CD254, RANKL
Size :
500 μg
Price (USD) :
340 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
LEAF
Immunogen :
NSO-derived recombinant mouse TRANCE
Application Notes :
The IK22/5 antibody has been reported to block the binding of RANK ligand-Fc to RANK. Additional reported applications (for the relevant formats) include: immunoprecipitation 2 , Western blotting 2 , and blocking of ligand binding 1,2,4 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 510009-510014).
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA