PE anti-mouse CD254 (TRANCE, RANKL) | BioLegend 510006 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse CD254 (TRANCE, RANKL)

catalog :

510006

quantity :

200 μg

price :

402 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

IK22/5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 3	Li J, Chassaing B, Tyagi A, Vaccaro C, Luo T, Adams J, et al. Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. J Clin Invest. 2016;126:2049-63 pubmed publisher
	Sapra L, Dar H, Bhardwaj A, Pandey A, Kumari S, Azam Z, et al. Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice. Sci Rep. 2021;11:1807 pubmed publisher
	Hinks T, Marchi E, Jabeen M, Olshansky M, Kurioka A, Pediongco T, et al. Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality. Cell Rep. 2019;28:3249-3262.e5 pubmed publisher
	Bieniasz Krzywiec P, Martín Pérez R, Ehling M, García Caballero M, Pinioti S, Pretto S, et al. Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer. Cell Metab. 2019;: pubmed publisher
	Dar H, Shukla P, Mishra P, Anupam R, Mondal R, Tomar G, et al. Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance. Bone Rep. 2018;8:46-56 pubmed publisher
	Dar H, Singh A, Shukla P, Anupam R, Mondal R, Mishra P, et al. High dietary salt intake correlates with modulated Th17-Treg cell balance resulting in enhanced bone loss and impaired bone-microarchitecture in male mice. Sci Rep. 2018;8:2503 pubmed publisher
	Ersching J, Basso A, Kalich V, Bortoluci K, Rodrigues M. A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells. PLoS Pathog. 2016;12:e1005698 pubmed publisher
	Takeshita S, Fumoto T, Naoe Y, Ikeda K. Age-related marrow adipogenesis is linked to increased expression of RANKL. J Biol Chem. 2014;289:16699-710 pubmed publisher
	Dai Y, Chen S, Kmieciak M, Zhou L, Lin H, Pei X, et al. The novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair. Mol Cancer Ther. 2013;12:878-89 pubmed publisher
	Gao Y, Grassi F, Ryan M, Terauchi M, Page K, Yang X, et al. IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation. J Clin Invest. 2007;117:122-32 pubmed

product information

Antigen :

CD254

Apps. Abbrev. :

Flow Cytometry

Cat # :

510006

Clone :

IK22/5

Item :

PE anti-mouse CD254 (TRANCE, RANKL)

Isotype :

Rat IgG2a, κ

Other Names :

Tumor necrosis factor-related activation-induced cytokine, Receptor activator of NF-κB ligand (RANK L), Osteoprotegerin ligand (OPGL), Osteoclast differentiation factor (ODF), SOFA, TNFSF-11, CD254, RANKL

Size :

200 μg

Price (USD) :

402 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

NSO-derived recombinant mouse TRANCE

Application Notes :

The IK22/5 antibody has been reported to block the binding of RANK ligand-Fc to RANK. Additional reported applications (for the relevant formats) include: immunoprecipitation 2 , Western blotting 2 , and blocking of ligand binding 1,2,4 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 510009-510014).

more info or order :

BioLegend product webpage