Purified anti-mouse CD254 (TRANCE, RANKL) | BioLegend 510002 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD254 (TRANCE, RANKL)

catalog :

510002

quantity :

500 μg

price :

136 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

IK22/5

reactivity :

mouse

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 9d	Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, et al. Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation. J Exp Med. 2018;215:481-500 pubmed publisher
flow cytometry; mouse; tbl s1	Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S. ICOS promotes group 2 innate lymphoid cell activation in lungs. Biochem Biophys Res Commun. 2015;463:739-45 pubmed publisher
	Jiang L, Yilmaz M, Uehara M, Cavazzoni C, Kasinath V, Zhao J, et al. Characterization of Leptin Receptor+ Stromal Cells in Lymph Node. Front Immunol. 2021;12:730438 pubmed publisher
	Bieniasz Krzywiec P, Martín Pérez R, Ehling M, García Caballero M, Pinioti S, Pretto S, et al. Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer. Cell Metab. 2019;: pubmed publisher
	Montero Herradón S, García Ceca J, Zapata A. Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation. Front Immunol. 2018;9:1020 pubmed publisher
	Singh K, Piprode V, Mhaske S, Barhanpurkar Naik A, Wani M. IL-3 Differentially Regulates Membrane and Soluble RANKL in Osteoblasts through Metalloproteases and the JAK2/STAT5 Pathway and Improves the RANKL/OPG Ratio in Adult Mice. J Immunol. 2018;200:595-606 pubmed publisher
	Lopes N, Vachon H, Marie J, Irla M. Administration of RANKL boosts thymic regeneration upon bone marrow transplantation. EMBO Mol Med. 2017;9:835-851 pubmed publisher
	Haslam S, Drolet A, Smith K, Tan M, Aupperlee M. Progestin-regulated luminal cell and myoepithelial cell-specific responses in mammary organoid culture. Endocrinology. 2008;149:2098-107 pubmed publisher
	Fionda C, Nappi F, Piccoli M, Frati L, Santoni A, Cippitelli M. 15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors. J Immunol. 2007;178:4039-50 pubmed

product information

Antigen :

CD254

Apps. Abbrev. :

Flow Cytometry, IP, Western Blotting

Cat # :

510002

Clone :

IK22/5

Item :

Purified anti-mouse CD254 (TRANCE, RANKL)

Isotype :

Rat IgG2a, κ

Other Names :

Tumor necrosis factor-related activation-induced cytokine, Receptor activator of NF-κB ligand (RANK L), Osteoprotegerin ligand (OPGL), Osteoclast differentiation factor (ODF), SOFA, TNFSF-11, CD254, RANKL

Size :

500 μg

Price (USD) :

136 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

NSO-derived recombinant mouse TRANCE

Application Notes :

The IK22/5 antibody has been reported to block the binding of RANK ligand-Fc to RANK. Additional reported applications (for the relevant formats) include: immunoprecipitation 2 , Western blotting 2 , and blocking of ligand binding 1,2,4 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 510009-510014).

more info or order :

BioLegend product webpage