product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human IL-9
catalog :
507602
quantity :
500 μg
price :
282 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MH9A4
reactivity :
human
application :
ELISA, flow cytometry, mass cytometry
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • mass cytometry; human; loading ...; fig 4e
Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed publisher
  • flow cytometry; human; loading ...; fig 7b
Lichnog C, Klabunde S, Becker E, Fuh F, Tripal P, Atreya R, et al. Cellular Mechanisms of Etrolizumab Treatment in Inflammatory Bowel Disease. Front Pharmacol. 2019;10:39 pubmed publisher
  • flow cytometry; human; loading ...; fig 3f
Stanko K, Iwert C, Appelt C, Vogt K, Schumann J, Strunk F, et al. CD96 expression determines the inflammatory potential of IL-9-producing Th9 cells. Proc Natl Acad Sci U S A. 2018;115:E2940-E2949 pubmed publisher
  • flow cytometry; human; fig 10
Gomez Rodriguez J, Meylan F, Handon R, Hayes E, Anderson S, Kirby M, et al. Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4. Nat Commun. 2016;7:10857 pubmed publisher
  • flow cytometry; human; loading ...; fig e2e
Mitson Salazar A, Yin Y, Wansley D, Young M, Bolan H, Arceo S, et al. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function. J Allergy Clin Immunol. 2016;137:907-18.e9 pubmed publisher
Roy S, Rizvi Z, Clarke A, MacDonald F, Pandey A, Zaiss D, et al. EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells. Nat Commun. 2021;12:3182 pubmed publisher
Rodriguez L, Pekkarinen P, Lakshmikanth T, Tan Z, Consiglio C, Pou C, et al. Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19. Cell Rep Med. 2020;1:100078 pubmed publisher
Ma X, Bi E, Huang C, Lu Y, Xue G, Guo X, et al. Cholesterol negatively regulates IL-9-producing CD8+ T cell differentiation and antitumor activity. J Exp Med. 2018;215:1555-1569 pubmed publisher
Lozano E, Dominguez Villar M, Kuchroo V, Hafler D. The TIGIT/CD226 axis regulates human T cell function. J Immunol. 2012;188:3869-75 pubmed publisher
Chen J, Petrus M, Bryant B, Phuc Nguyen V, Stamer M, Goldman C, et al. Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism. Blood. 2008;111:5163-72 pubmed publisher
product information
Antigen :
IL-9
Apps. Abbrev. :
ELISA Capture
Cat # :
507602
Clone :
MH9A4
Item :
Purified anti-human IL-9
Isotype :
Mouse IgG2b, κ
Other Names :
Interleukin-9, P40, Mast cell growth factor (MCGF), Megakaryoblast growth factor, T cell growth factor-3 (TCGF-3)
Size :
500 μg
Price (USD) :
282 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Baculovirus-expressed, recombinant human IL-9
Application Notes :
ELISA Capture 2 : The purified MH9A4 antibody is useful as the capture antibody in a human IL-9 sandwich ELISA assay, when used in conjunction with the biotinylated MH9D1 antibody as the detecting antibody. For human IL-9 neutralization assay, the LEAF purified MH9D1 antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for neutralization of human IL-9 bioactivity.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA