APC/Cyanine7 anti-mouse IL-17A | BioLegend 506940 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-mouse IL-17A

catalog :

506940

quantity :

100 μg

price :

347 USD

clonality :

monoclonal

host :

rat

conjugate :

APC/Cy7

clone name :

TC11-18H10.1

reactivity :

mouse

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 7a	Mize M, Sun X, Simecka J. Interleukin-17A Exacerbates Disease Severity in BALB/c Mice Susceptible to Lung Infection with Mycoplasma pulmonis. Infect Immun. 2018;86: pubmed publisher
	Bhaskar A, Pahuja I, Negi K, Verma A, Ghoshal A, Mathew B, et al. SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis. iScience. 2023;26:106644 pubmed publisher
	Ma S, Hernandez J, HUANG W. Protocol to assess cell-intrinsic regulatory mechanisms using an ex vivo murine T cell polarization and co-culture system. STAR Protoc. 2022;3:101543 pubmed publisher
	Hailemichael Y, Johnson D, Abdel Wahab N, Foo W, Bentebibel S, Daher M, et al. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022;40:509-523.e6 pubmed publisher
	Ma S, Patel S, Abe Y, Chen N, Patel P, Cho B, et al. RORγt phosphorylation protects against T cell-mediated inflammation. Cell Rep. 2022;38:110520 pubmed publisher
	Zhan Y, Zheng L, Liu J, Hu D, Wang J, Liu K, et al. PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+γδ Treg polarization. JCI Insight. 2021;6: pubmed publisher
	Mogilenko D, Shpynov O, Andhey P, Arthur L, Swain A, Esaulova E, et al. Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging. Immunity. 2021;54:99-115.e12 pubmed publisher
	Jin J, Jung I, Moon S, Jeon S, Jeong S, Sonn S, et al. CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs. Cell Rep. 2020;30:4124-4136.e5 pubmed publisher
	Antunes K, Fachi J, de Paula R, da Silva E, Pral L, dos Santos A, et al. Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response. Nat Commun. 2019;10:3273 pubmed publisher
	Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
	Ma Y, Zhang X, Bao H, Mi S, Cai W, Yan H, et al. Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice. PLoS ONE. 2012;7:e40763 pubmed publisher
	Cooney L, Towery K, Endres J, Fox D. Sensitivity and resistance to regulation by IL-4 during Th17 maturation. J Immunol. 2011;187:4440-50 pubmed publisher
	Cui Y, Shao H, Sun D, Kaplan H. Regulation of interphotoreceptor retinoid-binding protein (IRBP)-specific Th1 and Th17 cells in anterior chamber-associated immune deviation (ACAID). Invest Ophthalmol Vis Sci. 2009;50:5811-7 pubmed publisher
	Wang C, Kang S, Lee J, Sun Z, Kim C. The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut. Mucosal Immunol. 2009;2:173-83 pubmed publisher
	Smith E, Stark M, Zarbock A, Burcin T, Bruce A, Vaswani D, et al. IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor. J Immunol. 2008;181:1357-64 pubmed
	Kivisakk P, Imitola J, Rasmussen S, Elyaman W, Zhu B, Ransohoff R, et al. Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol. 2009;65:457-69 pubmed publisher
	Neufert C, Becker C, Wirtz S, Fantini M, Weigmann B, Galle P, et al. IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1. Eur J Immunol. 2007;37:1809-16 pubmed

product information

Antigen :

IL-17A

Apps. Abbrev. :

ICFC

Cat # :

506940

Clone :

TC11-18H10.1

Item :

APC/Cyanine7 anti-mouse IL-17A

Isotype :

Rat IgG1, κ

Other Names :

Interleukin-17, Cytotoxic T lymphocyte-associated antigen 8 (CTLA-8)

Size :

100 μg

Price (USD) :

347 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC_CYANINE7

Immunogen :

E. coli expressed, recombinant mouse IL-17A

Application Notes :

ELISA Capture^3,4 and ELISPOT Capture^5: The purified TC11-18H10.1 antibody is useful as the capture antibody in a sandwich ELISA, when used in conjunction with the biotinylated TC11-8H4 antibody (Cat. No. 507002) as the detecting antibody and recombinant mouse IL-17 (Cat. No. 576009) as the standard.Flow Cytometry^2-4,7,8,11,12: The TC11-18H10.1 antibody is useful for intracellular immunofluorescent staining and flow cytometric analysis to identify IL-17-producing cells within mixed cell populations.Neutralization^6,9: The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of mouse IL-17 bioactivity in vivo and in vitro (Cat. No. 506906).;

more info or order :

BioLegend product webpage