Biotin anti-mouse IL-12/IL-23 p40 | BioLegend 505301 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Biotin anti-mouse IL-12/IL-23 p40

catalog :

505301

quantity :

50 μg

price :

101 USD

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

C17.8

reactivity :

mouse

application :

ELISA

more info or order :

BioLegend product webpage

citations: 3

Reference
Yan H, Hu Y, Akk A, Ye K, Bacon J, Pham C. Interleukin-12 and -23 blockade mitigates elastase-induced abdominal aortic aneurysm. Sci Rep. 2019;9:10447 pubmed publisher
Liang D, Tian L, You R, Halpert M, Konduri V, Baig Y, et al. AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol. 2017;8:1801 pubmed publisher
Bourquin C, Schmidt L, Lanz A, Storch B, Wurzenberger C, Anz D, et al. Immunostimulatory RNA oligonucleotides induce an effective antitumoral NK cell response through the TLR7. J Immunol. 2009;183:6078-86 pubmed publisher

product information

Antigen :

IL-12/IL-23 p40

Apps. Abbrev. :

ELISA Detection, ELISPOT Detection, Intracellular Staining for Flow Cytometry

Cat # :

505301

Clone :

C17.8

Item :

Biotin anti-mouse IL-12/IL-23 p40

Isotype :

Rat IgG2a, κ

Other Names :

Interleukin-12 p40, Interleukin-23 p40, Cytotoxic lymphocyte maturation factor (CLMF), Natural killer cell stimulatory factor (NKSF), CTL maturation factor (TcMF), T-cell stimulating factor (TSF)

Size :

50 μg

Price (USD) :

101 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BIOTIN

Immunogen :

CHO expressed, recombinant mouse IL-12 p70

Application Notes :

ELISA Detection 1,2,6-9 or ELISPOT Detection: The biotinylated C17.8 antibody is useful as a detection antibody for a sandwich ELISA or ELISPOT assay, when used in conjunction with the purified C15.6 antibody (Cat. No. 505202/505208) as capture antibody and recombinant mouse IL-12/IL-23 p40 (Cat. No. 576909) or recombinant mouse IL-12 p70 (Cat. No. 577009) as the standard. Neutralization 1,2,4,5,6,10 : The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for neutralization of mouse IL-12 bioactivity in vivo and in vitro (Cat. No. 505304). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 505308) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug). Additional reported applications (for relevant formats of this clone) include: Western blotting 3 , immunoprecipitation 3 , and intracellular immunofluorescent staining and flow cytometric analysis. Note: For testing mouse IL-12 p40 (monomer, dimer, heterodimer) in serum or plasma, BioLegend s ELISA Max Sets (Cat. No. 431601 to 431606) are specially developed and recommended.

more info or order :

BioLegend product webpage