APC anti-mouse IL-12/IL-23 p40 | BioLegend 505206 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-mouse IL-12/IL-23 p40

catalog :

505206

quantity :

100 μg

price :

303 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

C15.6

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 5	Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed publisher
	den Hartigh A, Fink S. Pyroptosis Induction and Detection. Curr Protoc Immunol. 2018;122:e52 pubmed publisher
	Zhang J, Burn C, Young K, Wilson M, Ly K, Budhwani M, et al. Microparticles produced by human papillomavirus type 16 E7-expressing cells impair antigen presenting cell function and the cytotoxic T cell response. Sci Rep. 2018;8:2373 pubmed publisher
	Thwe P, Pelgrom L, Cooper R, Beauchamp S, Reisz J, D Alessandro A, et al. Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses. Cell Metab. 2017;26:558-567.e5 pubmed publisher
	Malu D, Bélanger B, Desautels F, Kelendji K, Dalko E, Sanchez Dardon J, et al. Macrophage migration inhibitory factor: a downregulator of early T cell-dependent IFN-gamma responses in Plasmodium chabaudi adami (556 KA)-infected mice. J Immunol. 2011;186:6271-9 pubmed publisher

product information

Antigen :

IL-12 IL-23 p40

Apps. Abbrev. :

Intracellular Staining for Flow Cytometry

Cat # :

505206

Clone :

C15.6

Item :

APC anti-mouse IL-12/IL-23 p40

Isotype :

Rat IgG1, κ

Other Names :

Interleukin-12 p40, Interleukin-23 p40, Cytotoxic lymphocyte maturation factor (CLMF), Natural killer cell stimulatory factor (NKSF), CTL maturation factor (TcMF), T-cell stimulating factor (TSF)

Size :

100 μg

Price (USD) :

303 USD

Reactivity :

Mouse, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40)

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

CHO-expressed, recombinant mouse IL-12 p70

Application Notes :

ELISA or ELISPOT Capture 1,2,4,6,8,10 : The purified C15.6 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated C17.8 (Cat. No. 505302) antibody as the detecting antibody. This assay detects p40 as monomer, homodimer, or heterodimer complexed with p35. The LEAF™ purified antibody is suggested for ELISPOT capture. Additional reported applications (for the relevant formats) include: immunohistochemical staining 9 of paraformaldehyde-fixed saponin-treated frozen tissue sections, immunoprecipitation 3 , and Western blotting 3 . Note: For testing mouse IL-12 p40 (monomer, dimer, heteromer) in serum or plasma, BioLegend s ELISA Max™ Sets (Cat. No. 431601 to 431606) are specially developed and recommended.

more info or order :

BioLegend product webpage