PE anti-mouse IL-12/IL-23 p40 | BioLegend 505204 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse IL-12/IL-23 p40

catalog :

505204

quantity :

100 μg

price :

283 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

C15.6

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 3c, 3d	Antony A, Lian Z, Perrard X, Perrard J, Liu H, Cox A, et al. Deficiency of Stat1 in CD11c+ Cells Alters Adipose Tissue Inflammation and Improves Metabolic Dysfunctions in Mice Fed a High-Fat Diet. Diabetes. 2021;70:720-732 pubmed publisher
	Hayashi K, Nikolos F, Lee Y, Jain A, Tsouko E, Gao H, et al. Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death. Nat Commun. 2020;11:6299 pubmed publisher
	Kim S, Saeidi S, Zhong X, Gwak S, Muna I, Park S, et al. Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages. Neoplasia. 2020;22:606-616 pubmed publisher
	Liu X, Boyer M, Holmgren A, Shin S. Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation. Cell Host Microbe. 2020;28:683-698.e6 pubmed publisher
	Etxeberria I, Bolaños E, Quetglas J, Gros A, Villanueva A, Palomero J, et al. Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells. Cancer Cell. 2019;36:613-629.e7 pubmed publisher
	Wang Q, He Z, Huang M, Liu T, Wang Y, Xu H, et al. Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α. Nat Commun. 2018;9:559 pubmed publisher
	de Mingo Pulido Á, Gardner A, Hiebler S, Soliman H, Rugo H, Krummel M, et al. TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. Cancer Cell. 2018;33:60-74.e6 pubmed publisher
	Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed publisher
	Aebischer D, Willrodt A, Halin C. Oxazolone-induced contact hypersensitivity reduces lymphatic drainage but enhances the induction of adaptive immunity. PLoS ONE. 2014;9:e99297 pubmed publisher
	Lee S, Carrero J, Uppaluri R, White J, Archambault J, Lai K, et al. Identifying the initiating events of anti-Listeria responses using mice with conditional loss of IFN-? receptor subunit 1 (IFNGR1). J Immunol. 2013;191:4223-34 pubmed publisher
	Magness S, Puthoff B, Crissey M, Dunn J, Henning S, Houchen C, et al. A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2013;305:G542-51 pubmed publisher
	Akilov O, Kasuboski R, Carter C, McDowell M. The role of mannose receptor during experimental leishmaniasis. J Leukoc Biol. 2007;81:1188-96 pubmed

product information

Antigen :

IL-12/IL-23 p40

Apps. Abbrev. :

Intracellular Staining for Flow Cytometry

Cat # :

505204

Clone :

C15.6

Item :

PE anti-mouse IL-12/IL-23 p40

Isotype :

Rat IgG1, κ

Other Names :

Interleukin-12 p40, Interleukin-23 p40, Cytotoxic lymphocyte maturation factor (CLMF), Natural killer cell stimulatory factor (NKSF), CTL maturation factor (TcMF), T-cell stimulating factor (TSF)

Size :

100 μg

Price (USD) :

283 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

CHO-expressed, recombinant mouse IL-12 p70

Application Notes :

ELISA or ELISPOT Capture 1,2,4,6,8,10 : The purified C15.6 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated C17.8 (Cat. No. 505302) antibody as the detecting antibody. This assay detects p40 as monomer, homodimer, or heterodimer complexed with p35. The LEAF purified antibody is suggested for ELISPOT capture. Additional reported applications (for the relevant formats) include: immunohistochemical staining 9 of paraformaldehyde-fixed saponin-treated frozen tissue sections, immunoprecipitation 3 , and Western blotting 3 . Note: For testing mouse IL-12 p40 (monomer, dimer, heteromer) in serum or plasma, BioLegend s ELISA Max Sets (Cat. No. 431601 to 431606) are specially developed and recommended.

more info or order :

BioLegend product webpage