Ultra-LEAF™ Purified anti-mouse IL-2 | BioLegend 503707 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-mouse IL-2

catalog :

503707

quantity :

5 mg

price :

539 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

JES6-1A12

reactivity :

mouse

application :

western blot, ELISA, neutralization, immunoprecipitation

more info or order :

BioLegend product webpage

citations: 3

Reference
Kawakami R, Kitagawa Y, Chen K, Arai M, Ohara D, Nakamura Y, et al. Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells. Immunity. 2021;54:947-961.e8 pubmed publisher
Katagiri T, Yamazaki S, Fukui Y, Aoki K, Yagita H, Nishina T, et al. JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling. Mucosal Immunol. 2019;12:1104-1117 pubmed publisher
Moore M, Blachere N, Fak J, Park C, Sawicka K, Parveen S, et al. ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity. elife. 2018;7: pubmed publisher

product information

Antigen :

IL-2

Apps. Abbrev. :

ELISA Capture, ELISPOT Capture, IP, Neut, Western Blotting

Cat # :

503707

Clone :

JES6-1A12

Item :

Ultra-LEAF™ Purified anti-mouse IL-2

Isotype :

Rat IgG2a, κ

Other Names :

Interleukin-2, T cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF)

Size :

5 mg

Price (USD) :

539 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

ULEAF

Immunogen :

E. coli -expressed, recombinant mouse IL-2

Application Notes :

ELISA Capture 1-3 or ELISPOT Capture 4-6 : The purified JES6-1A12 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated JES6-5H4 antibody (Cat. No. 503804) as the detecting antibody and recombinant mouse IL-2 (Cat. No.575409) as the standard. The LEAF™ purified antibody is suggested for ELISPOT capture (Cat. No. 503704). Neutralization: The JES6-1A12 antibody can neutralize the bioactivity of natural or recombinant IL-2. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 503706) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg).

more info or order :

BioLegend product webpage