product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse IL-2
catalog :
503702
quantity :
500 μg
price :
143 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
JES6-1A12
reactivity :
mouse
application :
western blot, ELISA, immunoprecipitation
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • ELISA; mouse; fig 5h
Phan T, Schink L, Mann J, Merk V, Zwicky P, Mundt S, et al. Keratinocytes control skin immune homeostasis through de novo-synthesized glucocorticoids. Sci Adv. 2021;7: pubmed publisher
Newland S, Mohanta S, Clement M, Taleb S, Walker J, Nus M, et al. Type-2 innate lymphoid cells control the development of atherosclerosis in mice. Nat Commun. 2017;8:15781 pubmed publisher
Parrish H, Glassman C, Keenen M, Deshpande N, Bronnimann M, Kuhns M. A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization. PLoS ONE. 2015;10:e0132333 pubmed publisher
Nishio J, Feuerer M, Wong J, Mathis D, Benoist C. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J Exp Med. 2010;207:1879-89 pubmed publisher
Dal Secco V, Riccioli A, Padula F, Ziparo E, Filippini A. Mouse Sertoli cells display phenotypical and functional traits of antigen-presenting cells in response to interferon gamma. Biol Reprod. 2008;78:234-42 pubmed
Devine L, Thakral D, Nag S, Dobbins J, Hodsdon M, Kavathas P. Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding. J Immunol. 2006;177:3930-8 pubmed
product information
Antigen :
IL-2
Apps. Abbrev. :
ELISA Capture, IP, Western Blotting
Cat # :
503702
Clone :
JES6-1A12
Item :
Purified anti-mouse IL-2
Isotype :
Rat IgG2a, κ
Other Names :
Interleukin-2, T cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF)
Size :
500 μg
Price (USD) :
143 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
E. coli -expressed, recombinant mouse IL-2
Application Notes :
ELISA Capture 1-3 or ELISPOT Capture 4-6 : The purified JES6-1A12 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated JES6-5H4 antibody (Cat. No. 503804) as the detecting antibody and recombinant mouse IL-2 (Cat. No.575409) as the standard. The LEAF™ purified antibody is suggested for ELISPOT capture (Cat. No. 503704). Neutralization: The JES6-1A12 antibody can neutralize the bioactivity of natural or recombinant IL-2. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 503706) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA